Vaccine News and Research

Latest Vaccine News and Research

Study sheds light on oral vaccine failure in mouse model of chronic gut disorder

A chronic gut disorder that occurs in regions with poor sanitation disrupts intestinal immune responses and impairs oral vaccine effectiveness in a mouse model of the disease, according to research led by UPMC Children's Hospital of Pittsburgh and University of Pittsburgh School of Medicine scientists.

3 Aug 2021

SARS-CoV-2 Delta and Delta AY.1 variant show similar Covaxin-induced neutralization

A new study from India suggests that the Indian-made Covaxin whole-virus inactivated vaccine against the SARS-CoV-2 retains significant efficacy against the newer delta variants of the virus.

3 Aug 2021

What is the potential of microphysiological systems in COVID-19 research?

In a recently published review article in the journal Drug Discovery Today, scientists have described the utility of human-based microphysiological systems MPSs in understanding the pathophysiology of SARS-CoV-2 infection and developing effective therapeutic interventions. Moreover, they have described the establishment of a global working group to synchronize recent developments around MPSs and COVID-19 research.

3 Aug 2021

Study examines efficacy Pfizer-BioNTech vaccine among USAF Academy Cadets

A new study published on the medRxiv* preprint server has estimated the effectiveness of vaccines in preventing COVID-19 as a function of time since vaccination.

3 Aug 2021

Unvaccinated and vaccinated have similar viral load in communities high in SARS-CoV-2 delta

The findings reveal that vaccinated and unvaccinated individuals exhibit similar viral loads following delta infection and that vaccine breakthrough cases have the potential to transmit infection to others. The study is currently available on the medRxiv* preprint server.

3 Aug 2021

National Qatari study shows vaccination reduces risk of spreading SARS-CoV-2 infection

A team of scientists from Qatar and the United States has recently studied the viral transmission potential of individuals with primary severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, reinfection, or vaccine breakthrough infection.

2 Aug 2021

CHOP researchers identify two proteins that could be used for a potential NTHi vaccine

Scientists at Children's Hospital of Philadelphia have identified two proteins that could be used for a potential vaccine against nontypeable Haemophilus influenzae (NTHi).

2 Aug 2021

Study shows efficacy of Pfizer-BioNTech and Moderna vaccines against SARS-CoV-2 delta variant

Researchers in Singapore have conducted a study showing that the messenger RNA- (mRNA) based coronavirus disease 2019 (COVID-19) vaccines developed by Pfizer-BioNTech and Moderna are highly effective at protecting against symptomatic and severe disease following infection with the rapidly spreading B.1.617.2 (delta) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

2 Aug 2021

Cancer vaccine reduces tumor burden, improves survival in animal model of Lynch syndrome

A new strategy for developing vaccines against cancer showed promise in a proof-of-concept study led by scientists at Weill Cornell Medicine, NewYork-Presbyterian and Heidelberg University Hospital.

2 Aug 2021

New model can help clinicians to predict 40-day mortality risk in hospitalized COVID-19 patients

Researchers from Hackensack Meridian University Medical Center and Berry Consultants, LLC, Austin, Texas have developed a new model to help clinicians predict the risk of death within 40 days in patients who are hospitalized with COVID-19 infection.

2 Aug 2021

Researchers discover titanium oxide nanoparticle that recognizes SARS-CoV-2’s non-structural protein 1

A pioneering study reports on the interaction of a tailored titanium oxide nanoparticle (NP) with the full-length SARS-CoV-2 non-structural protein 1 (nsp1). This should be of value in developing new therapeutic tools against coronaviruses that act by targeting their proteins. It could also help map the structure of activated proteins.

2 Aug 2021

Polyuridine sequence of mouse coronavirus can be targeted to prevent host cell death

A new study reports the use of a modified deoxyribonucleic acid (DNA) oligonucleotide that has a 3’ polyadenine (polyA) tail to bind to the 5’-polyU tract in the mouse coronavirus (MHV-A59). Treatment of mouse cells infected with MHV-A59 with this molecule led to a marked reduction in cell deaths.

2 Aug 2021

Could novel biosensors facilitate SARS-CoV-2 antiviral drug research?

An intriguing new study presents a novel approach to biosensor-based evaluation of promising drugs that could inhibit the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) via its 3C-like protease (3CLpro), a viral protease.

2 Aug 2021

Intradermal administration of low-dose mRNA COVID-19 vaccine induces strong immune response, study finds

Scientists in the Netherlands recently conducted an open-level, randomized-controlled trial to evaluate the safety and immunogenicity of fractional intradermal doses of the mRNA-based COVID-19 vaccine mRNA-1273 (Moderna). The trial findings reveal that the fractional dose regimen of the Moderna vaccine is well tolerated and safe and is capable of inducing robust antibody responses in vaccine recipients. The study is currently available on the medRxiv* preprint server.

2 Aug 2021

Study examined 1,497 full-vaccinated healthcare workers for breakthrough infections

A new study published in The New England Journal of Medicine found that in a very small number of cases, people with breakthrough infections might suffer long-lasting COVID-19 symptoms.

2 Aug 2021

Older adults with prior SARS-CoV-2 infection benefit from two doses of Pfizer/BioNTech vaccine

The study by researchers from the Ministry of Health, Madrid, Spain, published in the Center of Disease Control and Prevention’s journal Emerging Infectious Diseases, suggests that long-term care facility residents with prior SARS-CoV-2 infection benefit from full vaccination with the Pfizer/BioNTech (BNT162b2) vaccine.

2 Aug 2021

Public and private SARS-CoV-2 T cell receptors may be crucial for pan-coronavirus vaccines

Researchers have just established a structural basis for two spike glycoprotein epitopes of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that are restricted to human leukocyte antigen (HLA) A2 molecules. More specifically, they are involved in the presentation of antigenic peptides to specific T lymphocytes and recognized by public and private T cell receptors. The research is currently available on the bioRxiv* preprint server.

2 Aug 2021

Antibody responses following SARS-CoV-2 infection more potent than vaccine-elicited ones

Researchers in the United States have conducted a study showing the difference in antibody evolution following vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) between people who have not previously been infected with the virus and those who have.

1 Aug 2021

Risk of myocarditis from SARS-CoV-2 infection is higher in young males, a study finds

The study highlights that young males with COVID-19 are more susceptible to develop myocarditis than those who received mRNA-based COVID-19 vaccines.

1 Aug 2021

Risk of venous thrombosis is higher in SARS-CoV-2 infection than vaccination

A study has revealed that adenovirus vector and mRNA-COVID-19 vaccines are associated with an increased risk of thromboembolism and thrombocytopenia.

1 Aug 2021

Vaccine News and Research

Latest Vaccine News and Research

Study sheds light on oral vaccine failure in mouse model of chronic gut disorder

SARS-CoV-2 Delta and Delta AY.1 variant show similar Covaxin-induced neutralization

What is the potential of microphysiological systems in COVID-19 research?

Study examines efficacy Pfizer-BioNTech vaccine among USAF Academy Cadets

Unvaccinated and vaccinated have similar viral load in communities high in SARS-CoV-2 delta

National Qatari study shows vaccination reduces risk of spreading SARS-CoV-2 infection

CHOP researchers identify two proteins that could be used for a potential NTHi vaccine

Study shows efficacy of Pfizer-BioNTech and Moderna vaccines against SARS-CoV-2 delta variant

Cancer vaccine reduces tumor burden, improves survival in animal model of Lynch syndrome

New model can help clinicians to predict 40-day mortality risk in hospitalized COVID-19 patients

Researchers discover titanium oxide nanoparticle that recognizes SARS-CoV-2’s non-structural protein 1

Polyuridine sequence of mouse coronavirus can be targeted to prevent host cell death

Could novel biosensors facilitate SARS-CoV-2 antiviral drug research?

Intradermal administration of low-dose mRNA COVID-19 vaccine induces strong immune response, study finds

Study examined 1,497 full-vaccinated healthcare workers for breakthrough infections

Older adults with prior SARS-CoV-2 infection benefit from two doses of Pfizer/BioNTech vaccine

Public and private SARS-CoV-2 T cell receptors may be crucial for pan-coronavirus vaccines

Antibody responses following SARS-CoV-2 infection more potent than vaccine-elicited ones

Risk of myocarditis from SARS-CoV-2 infection is higher in young males, a study finds

Risk of venous thrombosis is higher in SARS-CoV-2 infection than vaccination

Event guide: 3rd mRNA Process Development & Manufacturing Europe eBook

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

Vaccine News and Research

Latest Vaccine News and Research

Event guide: 3rd mRNA Process Development & Manufacturing Europe eBook

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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