Vaccine News and Research

Latest Vaccine News and Research

mRNA vaccines shown to be 97% protective against COVID-19 in working-age population

Researchers in the United States have demonstrated the effectiveness of messenger RNA (mRNA)-based vaccination at protecting against infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among almost 47,000 healthcare workers.

7 Jun 2021

Study observes broad and invariable memory B cell response following SARS-CoV-2 infection

A new study by researchers at the Oregon Health & Science University (OHSU) in the USA goes far in answering this question by showing the presence of memory B cells that react to the original SARS-CoV-2 as well as VOCs.

7 Jun 2021

Could COVID-19 vaccinations or prior infections protect against other coronaviruses?

A new study provides encouraging proof of the feasibility of this project, showing that both natural infection with and vaccination against SARS-CoV-2 are associated with an increase in cross-reactive antibodies against other CoVs.

7 Jun 2021

Single BioNTech/Pfizer vaccine dose reduces risk of COVID-19 by nearly 52%, matching clinical trial data

Data gathered from real-world vaccination programs following a single dose of Pfizer vaccine administration shows a reduction of 51.4% in infection risk and effectiveness of 54.4% against symptomatic coronavirus disease 2019 (COVID-19), matching clinical trial results.

7 Jun 2021

Study explores therapeutic potential of exploiting autophagy cascade against COVID-19

Researchers recently reviewed current knowledge on links between autophagy and coronaviruses and how this knowledge can be used to repurpose autophagy modulators as potential treatment options for COVID-19. The review is published in the journal Frontiers in Microbiology.

7 Jun 2021

Vaccination against SARS-CoV-2 with a single dose skin patch

Researchers from Australia recently reported a high-density microarray patch used to deliver a SARS-CoV-2 spike subunit vaccine to the skin directly. They used a combination of a SARS-CoV-2 spike protein vaccine candidate and the high-density microarray patch (HD-MAP) vaccine delivery platform.

7 Jun 2021

Comparison of immunological profiles of SARS-CoV-2 variants

Mutations to the spike protein and receptor-binding domain are responsible for these changes in immunogenic profile, and in a paper recently uploaded to the open access journal Antibiotics by Ambrose et al. (May 6th, 2021) these mutations are correlated with various disease parameters by in silico methods, finding that particular features are responsible for the increased infectiousness and lesser disease severity observed in these lineages.

6 Jun 2021

Standardizable assay detects T cell responses to SARS-CoV-2 infection

Researchers in the UK have developed a high-throughput standardizable assay that accurately detects T cell responses to infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

6 Jun 2021

New data from CDC on effectiveness of Pfizer and Moderna COVID-19 vaccines

Researchers in the United States have conducted a study demonstrating the real-world effectiveness of the Pfizer-BioNTech and Moderna coronavirus disease 2019 (COVID-19) vaccines at preventing infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

6 Jun 2021

Georgia State professor receives federal grant to study seasonal and universal vaccination in elderly populations

Dr. Sang-Moo Kang, professor in the Institute for Biomedical Sciences at Georgia State University, has received a five-year, $2.7 million federal grant to study seasonal and universal vaccination in elderly populations with pre-existing immunity to influenza viruses.

5 Jun 2021

Maternal SARS-CoV-2 infection imprints immune response in the newborn

A new bioRxiv* preprint reports the immunological footprint in the newborn left by maternal infection with SARS-CoV-2 during pregnancy.

4 Jun 2021

In Missouri and other states, flawed data makes it hard to track vaccine equity

Throughout the covid-19 vaccination effort, public health officials and politicians have insisted that providing shots equitably across racial and ethnic groups is a top priority.

4 Jun 2021

Methotrexate users fail to achieve adequate immune response to mRNA COVID-19 vaccines

Up to a third of patients taking methotrexate – a common treatment for immune mediated inflammatory conditions such as rheumatoid arthritis and psoriasis/psoriatic arthritis – failed to achieve an adequate immune response to mRNA COVID-19 vaccines in a small study accepted for publication in the journal Annals of the Rheumatic Diseases.

4 Jun 2021

Three cases of stroke reported in young adults following covid-19 vaccination

Clots in the arteries (arterial thrombosis) are the most common cause of stroke (ischemic stroke) and have been reported in detail for the first time in young adults who received the Oxford–AstraZeneca covid-19 vaccine in a letter from UK stroke specialists published online in Journal of Neurology Neurosurgery & Psychiatry.

4 Jun 2021

Investigative journalist looks at independency of US and British vaccine advisory committees

Experts who sit on national vaccine advisory panels are asked to disclose any industry ties and other conflicts of interest. But an investigation published by The BMJ today finds that disclosure standards differ widely, often leaving the public in the dark.

4 Jun 2021

Clinical trial evaluating mixed COVID-19 vaccine schedules begins at NIH

Vaccination efforts against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus behind the coronavirus disease (COVID-19) pandemic, are well underway in many countries. Over 2 billion vaccines have been administered to date, and campaigns continue to encourage more people to get vaccinated.

4 Jun 2021

New strategy for developing universal flu vaccine

A new study from the University of Chicago and Scripps Research Institute shows that during the last great pandemic--2009's H1N1 influenza pandemic--people developed strong, effective immune responses to stable, conserved parts of the virus.

4 Jun 2021

Study says COVID-19 vaccines passports will likely reduce inclination to accept vaccines

Now, a new study published on medRxiv* preprint server focuses on the quantitative evaluation of the impact of the implementation of vaccine passports for domestic and international travel.

4 Jun 2021

People who received Pfizer-Biontech vaccine have lower antibody levels targeting the delta variant

Levels of antibodies in the blood of vaccinated people that are able to recognise and fight the new SARS-CoV-2 Delta variant first discovered in India (B.1.617.2) are on average lower than those against previously circulating variants in the UK, according to new laboratory data from the Francis Crick Institute and the National Institute for Health Research (NIHR) UCLH Biomedical Research Centre, published today (Thursday) as a Research letter in The Lancet.

4 Jun 2021

Heterologous AstraZeneca and Pfizer vaccines induce strong immune response and T cell reactivity against multiple SARS-CoV-2 variants

Researchers from Germany recently analyzed a cohort of 26 individuals in the age range of 25 to 46 (median 30.5) years who had received a ChAdOx1 nCoV-19 prime vaccine followed by a BNT162b2 boost vaccine after a 56-day interval due to changing vaccine recommendations in Germany. There were 16 females and 10 males in the cohort, and they were assessed for immune responses, reactogenicity, and T cell reactivity. This study is published on the medRxiv* preprint server.

3 Jun 2021

Vaccine News and Research

Latest Vaccine News and Research

mRNA vaccines shown to be 97% protective against COVID-19 in working-age population

Study observes broad and invariable memory B cell response following SARS-CoV-2 infection

Could COVID-19 vaccinations or prior infections protect against other coronaviruses?

Single BioNTech/Pfizer vaccine dose reduces risk of COVID-19 by nearly 52%, matching clinical trial data

Study explores therapeutic potential of exploiting autophagy cascade against COVID-19

Vaccination against SARS-CoV-2 with a single dose skin patch

Comparison of immunological profiles of SARS-CoV-2 variants

Standardizable assay detects T cell responses to SARS-CoV-2 infection

New data from CDC on effectiveness of Pfizer and Moderna COVID-19 vaccines

Georgia State professor receives federal grant to study seasonal and universal vaccination in elderly populations

Maternal SARS-CoV-2 infection imprints immune response in the newborn

In Missouri and other states, flawed data makes it hard to track vaccine equity

Methotrexate users fail to achieve adequate immune response to mRNA COVID-19 vaccines

Three cases of stroke reported in young adults following covid-19 vaccination

Investigative journalist looks at independency of US and British vaccine advisory committees

Clinical trial evaluating mixed COVID-19 vaccine schedules begins at NIH

New strategy for developing universal flu vaccine

Study says COVID-19 vaccines passports will likely reduce inclination to accept vaccines

People who received Pfizer-Biontech vaccine have lower antibody levels targeting the delta variant

Heterologous AstraZeneca and Pfizer vaccines induce strong immune response and T cell reactivity against multiple SARS-CoV-2 variants

Event guide: 3rd mRNA Process Development & Manufacturing Europe eBook

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

Todd Bauman and Chris Povich

Vaccine News and Research

Latest Vaccine News and Research

Event guide: 3rd mRNA Process Development & Manufacturing Europe eBook

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

Todd Bauman and Chris Povich

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