Vaccine News and Research

Latest Vaccine News and Research

Vaccination of health care workers resulted in notable reduction of COVID-19 cases

Vaccinating health care workers resulted in an immediate and notable reduction of positive COVID-19 cases among employees, reducing the number of required isolations and quarantines by more than 90 percent, according to data at UT Southwestern Medical Center published in the New England Journal of Medicine.

24 Mar 2021

SARS-CoV-2 infection after vaccination is possible, shows study

In a letter to The New England Journal of Medicine, published online March 23, 2021, a group of investigators from University of California San Diego School of Medicine and the David Geffen School of Medicine at UCLA report COVID-19 infection rates for a cohort of health care workers previously vaccinated for the novel coronavirus.

24 Mar 2021

Potent nanobody binds SARS-CoV-2 spike in an extraordinary manner

In a new study, published recently on the bioRxiv preprint server, researchers isolated a nanobody that potently neutralizes SARS-CoV-2, including the B.1.351 variant, and cross-neutralizes SARS-CoV. They demonstrated the therapeutic potential of the nanobody in a human ACE2 (angiotensin-converting enzyme) transgenic mouse model.

24 Mar 2021

People who received flu shot last season had fewer complication of COVID-19

People who received a flu shot last flu season were significantly less likely to test positive for a COVID-19 infection when the pandemic hit, according to a new study.

23 Mar 2021

CureVac's COVID-19 vaccine protects mice against emerging SARS-CoV-2 variants

The CVnCoV mRNA vaccine showed neutralizing antibody levels and completely protected mice infected with the B.1.351 variant. No viral genomes were seen in oral swabs, lungs, or brain.

23 Mar 2021

Survey findings reveals persistence of COVID-19 vaccine hesitancy

Daily national surveys by Carnegie Mellon University show that while COVID-19 vaccine uptake has increased, the proportion of vaccine-hesitant adults has remained unchanged. The concerns about a side effect remain high, especially among females, Black adults and those with an eligible health condition.

23 Mar 2021

Study shows single dose of mRNA vaccine may suffice for those with prior SARS-CoV-2 infection

A recent study by researchers from Philadelphia, currently available on the medRxiv preprint server, shows that individuals with prior infection caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibit substantial immune memory and develop a robust response to the first dose of an mRNA vaccine.

23 Mar 2021

Computational analysis reveals why new SARS-CoV-2 variants bind better to human cells

All viruses mutate as they make copies of themselves to spread and thrive. SARS-CoV-2, the virus the causes COVID-19, is proving to be no different. There are currently more than 4,000 variants of COVID-19, which has already killed more than 2.7 million people worldwide during the pandemic.

23 Mar 2021

Pfizer coronavirus vaccine found to be moderately less effective against South African variant

Ben-Gurion University of the Negev (BGU) researchers have found that the Pfizer Coronavirus vaccine is moderately less effective against the South African variant, but still neutralizes the British variant and the original SARS-CoV-2 strain.

23 Mar 2021

Is T-cell receptor sequencing a reliable alternative to SARS-CoV-2 antibody testing?

Researchers in the United States have now demonstrated that T-cell receptor (TCR) sequencing might provide a reliable alternative to assessing infection in convalescent blood plasma, and may be applicable in the future for applying protective immunity to individuals.

23 Mar 2021

Correlation of antibody titers with COVID-19 vaccine efficacy

In a new study the relationship between virus-neutralizing antibody and spike protein-binding IgG antibody levels is explored following vaccination by one of seven currently deployed vaccines. The findings support the use of antibody titers as correlates of protection for COVID-19 vaccines.

23 Mar 2021

COVID-19 vaccines reduce virus transmission in healthcare worker case study

In a new study, the ability of COVID-19 vaccines to lessen transmission was examined in a large study of healthcare workers and their families, with promising results that indicate a substantially reduced rate of transmission from the vaccinated to the non-vaccinated.

23 Mar 2021

A new COVID-19 candidate vaccine induces robust humoral and cellular immune responses in mice

A Korea-based company EyeGene Inc. has recently developed a liposome-based mRNA candidate vaccine against COVID-19, which contains full-length spike protein of the European variant (D614G) of SARS-CoV-2 as a vaccine antigen.

23 Mar 2021

‘An Arm and a Leg’: In vaccinating Philadelphia, a mix of the good, the bad and the ugly

In Philadelphia, the good, the bad and the ugly have all been on vivid display in the covid vaccine rollout.

23 Mar 2021

‘Press 1 for English’: Vaccination sign-ups prove daunting for speakers of other languages

In late February, a week after Virginia launched a centralized website and call center for covid-19 vaccine preregistration, Zowee Aquino alerted the state to a glitch that could prove fatal for non-English speakers trying to secure a shot.

23 Mar 2021

Democrats eye Medicare negotiations to lower drug prices

Democrats, newly in control of Congress and the White House, are united behind an idea that Republican lawmakers and major drugmakers fiercely oppose: empowering the Department of Health and Human Services to negotiate the prices of brand-name drugs covered by Medicare.

23 Mar 2021

Widening ideological gap in the U.S. may contribute to challenges in medical research

The lightning speed with which scientists developed and tested the COVID-19 vaccine is a true scientific triumph -- one that would not have been possible without the more than 70,000 volunteers who participated in clinical trials of the vaccine.

23 Mar 2021

Single BNT162b2 mRNA dose induces humoral and T cell responses against mutated variants with a history of COVID-19

In a paper recently uploaded to the preprint server bioRxiv by Tauzin et al. (March 18th, 2021) the ability of a single dose of mRNA vaccine to induce humoral and T cell responses against mutated variants are demonstrated and found to be reinforced in individuals with a history of COVID-19.

22 Mar 2021

Simple SARS-CoV-2 mutations allow escape from the majority of polyclonal antibodies

The group identified a single class of antibodies that target a particular epitope on the RBD of SARS-CoV-2, suggesting that the human polyclonal response to SARS-CoV-2 infection is dominated by a worryingly narrow range of antibodies that target an epitope undergoing rapid mutation.

22 Mar 2021

B.1.1.7 SARS-CoV-2 variant significantly more dangerous

Now, researchers at the University of Exeter, the NHS Foundation Trust, report a significant increase in mortality risk due to the B.1.1.7 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant.

22 Mar 2021

Vaccine News and Research

Latest Vaccine News and Research

Vaccination of health care workers resulted in notable reduction of COVID-19 cases

SARS-CoV-2 infection after vaccination is possible, shows study

Potent nanobody binds SARS-CoV-2 spike in an extraordinary manner

People who received flu shot last season had fewer complication of COVID-19

CureVac's COVID-19 vaccine protects mice against emerging SARS-CoV-2 variants

Survey findings reveals persistence of COVID-19 vaccine hesitancy

Study shows single dose of mRNA vaccine may suffice for those with prior SARS-CoV-2 infection

Computational analysis reveals why new SARS-CoV-2 variants bind better to human cells

Pfizer coronavirus vaccine found to be moderately less effective against South African variant

Is T-cell receptor sequencing a reliable alternative to SARS-CoV-2 antibody testing?

Correlation of antibody titers with COVID-19 vaccine efficacy

COVID-19 vaccines reduce virus transmission in healthcare worker case study

A new COVID-19 candidate vaccine induces robust humoral and cellular immune responses in mice

‘An Arm and a Leg’: In vaccinating Philadelphia, a mix of the good, the bad and the ugly

‘Press 1 for English’: Vaccination sign-ups prove daunting for speakers of other languages

Democrats eye Medicare negotiations to lower drug prices

Widening ideological gap in the U.S. may contribute to challenges in medical research

Single BNT162b2 mRNA dose induces humoral and T cell responses against mutated variants with a history of COVID-19

Simple SARS-CoV-2 mutations allow escape from the majority of polyclonal antibodies

B.1.1.7 SARS-CoV-2 variant significantly more dangerous

Event guide: 3rd mRNA Process Development & Manufacturing Europe eBook

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

Todd Bauman and Chris Povich

Vaccine News and Research

Latest Vaccine News and Research

Event guide: 3rd mRNA Process Development & Manufacturing Europe eBook

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

Todd Bauman and Chris Povich

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