Vaccine News and Research

Latest Vaccine News and Research

Tamper-proof temperature indicator could help monitor ideal storage conditions of mRNA vaccines

Scientists have developed vaccines for COVID-19 with record speed. The first two vaccines widely distributed in the U.S. are mRNA-based and require ultracold storage (-70 C for one and -20 C for the other).

31 Mar 2021

New mRNA COVID-19 vaccine candidate shows promise in vivo

Researchers report that a new lipid nanoparticle mRNA coronavirus disease 2019 (COVID-19) vaccine candidate protected 70% of mice expressing the human angiotensin-converting enzyme 2 (ACE2), while all the non-vaccinated mice died.

31 Mar 2021

Researchers evaluate antibodies that inhibit SARS-CoV-2 RBD variants with a novel assay

A team of researchers recently discussed the potential role of a new assay in bridging a major gap in SARS-CoV-2 research. This assay can throw light on 1) the selection of complementary monoclonal antibody candidates and 2) rapid identification of the immune escape to emerging RBD variants following vaccination or natural infection.

31 Mar 2021

Infliximab may hinder the effectiveness of some COVID-19 vaccines

A new study reports reduced vaccine efficacy following the use of a single COVID-19 vaccine dose in people who are on the immunosuppressive monoclonal antibody Infliximab.

31 Mar 2021

Asymmetrical vaccine distribution could promote vaccine evading mutations in SARS-CoV-2

Researchers have investigated the ultimate influence of unequal vaccine distribution by mathematical modeling, revealing the critical role of fair distribution in future COVID-19 containment strategy.

31 Mar 2021

mRNA COVID-19 vaccines are highly effective among front liners, CDC study shows

The study, published in CDC's Morbidity and Mortality Weekly Report (MMWR), highlights the efficacy of mRNA vaccines in protecting against SARS-CoV-2 infection.

30 Mar 2021

SARS-CoV-2 mutation T478K spreading at alarming speed in Mexico

Several SARS-CoV-2 variants have emerged, posing a renewed threat to COVID-19 containment and to vaccine and drug efficacy. In this study, we analyzed more than 820,000 SARS-CoV-2 genomic sequences deposited up to March 26, 2021 and identified a novel T478K mutation located on the SARS-CoV-2 Spike protein.

30 Mar 2021

Comparing the transmission routes of two SARS-CoV-2 variants of concern

The research team had previously identified the UK variant as having higher viral RNA shedding than the D614G variant. However here, they wanted to compare the transmission of such variants through different routes of potential infection: direct contact, aerosol (airborne droplets), and fomite (objects which may be contaminated and therefore spread infectious agents).

30 Mar 2021

Survey: COVID-19 pandemic has led to more advanced-stage cancer diagnoses

Doctors who oversee cancer clinics say that new patients are arriving for treatment with more advanced disease than before the COVID-19 pandemic, according to a new survey from the American Society for Radiation Oncology.

30 Mar 2021

UCLA receives grant to study the effectiveness of COVID-19 vaccines among health care workers

The David Geffen School of Medicine at UCLA has received a $4.9 million grant from the Centers for Disease Control and Prevention to study the effectiveness of COVID-19 vaccines among health care workers.

30 Mar 2021

Imported COVID-19 cases responsible for spread of the UK and Brazil SARS-CoV-2 variants in Italy

A new study examines a major consequence of the second wave of COVID-19 infection—namely, the rapid emergence of new viral lineages and variants.

30 Mar 2021

Single dose of Pfizer and Oxford vaccines shows 60% efficacy in elderly care home residents

A new study deals with the effect of two widely used vaccines in eliciting humoral immunity against the virus in this group. These are the Oxford/AstraZeneca viral-vectored vaccine (ChAdOx1 nCoV-19), and the Pfizer/BioNTech’s messenger RNA-based vaccine (BNT162b2). Both express the viral spike antigen, and both are currently being employed in the UK’s vaccination program.

30 Mar 2021

Study finds rapid increase in IgG and IgA antibody levels following COVID-19 mRNA vaccination

A new study describes the kinetics of the antibody response to the earliest approved vaccines against COVID-19, which were developed on an mRNA platform.

30 Mar 2021

Researchers report on novel SARS-CoV-2 Israeli strain with unique spike glycoprotein

Researchers from Israel describe a novel SARS-CoV-2 strain with a non-synonymous mutation in its spike glycoprotein, designated as P681H; nevertheless, its emergence has not been associated with increased infections rate, facilitated spread or vaccine evasion.

30 Mar 2021

Vaccine News and Research

Latest Vaccine News and Research

Tamper-proof temperature indicator could help monitor ideal storage conditions of mRNA vaccines

New mRNA COVID-19 vaccine candidate shows promise in vivo

Researchers evaluate antibodies that inhibit SARS-CoV-2 RBD variants with a novel assay

Infliximab may hinder the effectiveness of some COVID-19 vaccines

Asymmetrical vaccine distribution could promote vaccine evading mutations in SARS-CoV-2

mRNA COVID-19 vaccines are highly effective among front liners, CDC study shows

SARS-CoV-2 mutation T478K spreading at alarming speed in Mexico

Comparing the transmission routes of two SARS-CoV-2 variants of concern

Survey: COVID-19 pandemic has led to more advanced-stage cancer diagnoses

UCLA receives grant to study the effectiveness of COVID-19 vaccines among health care workers

Imported COVID-19 cases responsible for spread of the UK and Brazil SARS-CoV-2 variants in Italy

Single dose of Pfizer and Oxford vaccines shows 60% efficacy in elderly care home residents

Study finds rapid increase in IgG and IgA antibody levels following COVID-19 mRNA vaccination

Researchers report on novel SARS-CoV-2 Israeli strain with unique spike glycoprotein

Researchers develop broadly neutralizing SARS-CoV-2 ferritin nanoparticle vaccine

Determination of vaccine-elicited SARS-CoV-2 antibodies in breastmilk

More people now willing to get vaccinated against SARS-CoV-2, study finds

Scientists develop new method to estimate prevalence of SARS-CoV-2 antibodies

Nanoparticles elicit neutralizing antibodies to diverse SARS-CoV-2 variants

Scientists study the sensitivity of SARS-CoV-2 variants to neutralize antibodies

Event guide: 3rd mRNA Process Development & Manufacturing Europe eBook

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

Todd Bauman and Chris Povich

Vaccine News and Research

Latest Vaccine News and Research

Event guide: 3rd mRNA Process Development & Manufacturing Europe eBook

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

Todd Bauman and Chris Povich

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