Vaccine News and Research

Latest Vaccine News and Research

Inviragen commences DENVax Phase 2 trial for dengue

Inviragen, Inc. today announced the initiation of a Phase 2, randomized, double-blind, placebo-controlled study of DENVax, the Company's investigational dengue vaccine.

28 Nov 2011

Suppressing mosquitoes - the only way of controlling dengue

There is no vaccine against dengue, an emerging tropical disease regularly also hitting tourists, so the only way of controlling it is by suppressing the mosquitoes transmitting the disease.

28 Nov 2011

Mass immunization with cervical cancer vaccine switched to a more effective variety

Cervarix is currently offered to girls aged 12 and 13 years to protect against strains of the sexually transmitted human papillomavirus (HPV), which causes most cases of cancer of the cervix, the neck of the womb. Cervarix was picked by the Labour government for the first four-year phase of the NHS programme in 2008 because it offered ‘best overall value’ and more than five million doses have been given.

27 Nov 2011

Immunicum receives Swedish approval to commence first clinical trial of patented cancer vaccine

Immunicum, which is developing cancer vaccines, has received approval from the Swedish Medical Products Agency to start its first clinical trial. The study will be conducted on kidney cancer patients at the University Hospital in Uppsala. At the same time, the company secures substantial financing to complete the clinical trial.

25 Nov 2011

NIH-led study advances HIV vaccine research

HIV is coated in sugars that usually hide the virus from the immune system. Newly published research reveals how one broadly neutralizing HIV antibody actually uses part of the sugary cloak to help bind to the virus. The antibody binding site, called the V1/V2 region, represents a suitable HIV vaccine target, according to the scientists who conducted the study. In addition, their research reveals the detailed structure of the V1/V2 region, the last part of the virus surface to be visualized at the atomic level.

24 Nov 2011

MC3R gene plays an important role in maintaining steady weight

Against the backdrop of the growing epidemic of obesity in the United States, scientists from the Florida campus of The Scripps Research Institute have made an important new discovery regarding a specific gene that plays an important role in keeping a steady balance between our food intake and energy expenditure. The study may help scientists better understand the keys to fighting obesity and related disorders such as diabetes.

24 Nov 2011

JIB highlights aluminium's potential role in neurodegenerative diseases

Aluminium's potential role in neurodegenerative diseases such as Alzheimer's disease and cancer, specifically breast cancer, and the potential role for aluminium adjuvants in vaccine-related adverse effects are spotlighted in the latest issue of the Journal of Inorganic Biochemistry (JIB).

23 Nov 2011

Balanced approach needed to fight cholera outbreaks in Haiti

Jason Nickerson, a respiratory therapist and doctoral candidate in Population Health at the University of Ottawa, in this Global Health Hub post, recounts recent controversy surrounding "the health and humanitarian response to the earthquake and cholera outbreaks" in Haiti, noting tension "between the provision of [a cholera] vaccine as opposed to spending the money on improvements to water and sanitation" in the country.

23 Nov 2011

University of Rochester receives U.S. patent for HPV vaccine research

The University of Rochester has been awarded a U.S. patent for research essential to both human papillomavirus vaccines on the market.

23 Nov 2011

Panel discussion highlights USAID achievements on 50Th anniversary

This post in the Malaria Policy Center blog summarizes a panel discussion, titled "Partnerships for Global Health Success: Spotlight on USAID," that took place Monday in Washington, D.C., and was sponsored by Research!America.

23 Nov 2011

Medicare to cover infusion costs for prostate cancer vaccine, company says

In Medicare news, the drug maker Dendreon says federal officials have said they will pay doctors to administer the drug. Also, policymakers are studying Medigap to see if curbs on those policies could help cut Medicare costs.

23 Nov 2011

Arginine may reactivate T-cells in patients with glioblastoma

In many cases, tumors suppress a patient's immune system in a way that keeps the cancer safe from immune system attack. This is particularly true for patients with glioblastoma, a primary brain tumor that carries a prognosis of only 12-15 months survival after diagnosis.

22 Nov 2011

FDA accepts Regeneron's ARCALYST sBLA for review

Regeneron Pharmaceuticals, Inc. announced that the U.S. Food and Drug Administration (FDA) has accepted for review the Company's supplemental Biologics License Application (sBLA) for ARCALYST Injection for Subcutaneous Use for the prevention of gout flares in patients initiating uric acid-lowering therapy.

22 Nov 2011

Number of annual polio cases in Nigeria quadruples; WHO, government working to vaccinate millions of children

Nigeria has reported 43 cases of polio so far this year, up from 11 cases in 2010, and the disease has spread to Niger, Mali, and Cote d'Ivoire, according to a WHO official, BBC News reports.

22 Nov 2011

Fight against HIV/AIDS continues with successes and failures: UNAIDS report

An annual report released Monday by UNAIDS, the United Nations agency fighting AIDS has revealed that the world’s AIDS epidemic has hit a plateau, with 2.7 million people becoming newly infected each year for the last five years.

22 Nov 2011

Study: Vaccine development efforts currently focus on incidence rather than mortality rates

Drug companies currently developing therapeutic cancer vaccines may be determining the cancers they target based on the number of annual cases, not the number of deaths they cause.

22 Nov 2011

Scientists identify new immune system defect in aged mice

As people age, their immune system becomes less robust. This makes them more susceptible to serious and frequently life-threatening infections with viruses that affect the respiratory tract such as influenza A virus.

22 Nov 2011

Significant drops seen in AIDS-related deaths, new HIV infections, UNAIDS report shows

UNAIDS on Monday released its World AIDS Day Report 2011, "which shows more people than ever living with HIV, but deaths and new infections steadily dropping," the Guardian reports.

22 Nov 2011

Wall Street Journal CEO Council highlights global health as priority area

The Wall Street Journal last week held its CEO Council, "assembl[ing] nearly 100 chief executives of large companies for a day and a half to discuss the policy choices facing business and government, and the effects those choices may have on the global economy."

21 Nov 2011

Consistent data from three studies support plans for rindopepimut with ACT IV Phase 3 study

Celldex Therapeutics, Inc. today announced the presentation of mature overall survival (OS) data for ACT III, a multi-center, single arm, Phase 2 clinical trial of rindopepimut (CDX-110) in patients with newly diagnosed EGFRvIII-positive glioblastoma (GB).

21 Nov 2011