Vasculitis News and Research

Latest Vasculitis News and Research

Mouse model of fatal COVID-19 developed for vaccine and drug testing

Now, a new study published on the preprint server bioRxiv in July 2020 presents an engineered transgenic mouse that reproduces the functional and clinical characteristics of severe human SARS-CoV-2 infection.

21 Jul 2020

Study explains why fetuses and newborns are mostly spared by COVID-19

Amid the coronavirus pandemic, it has been previously suggested that the most vulnerable individuals to developing severe coronavirus disease (COVID-19) include the elderly, those with underlying health conditions, and those who have weakened immune systems.

15 Jul 2020

Research sheds light on mysterious COVID-19 related hyperinflammatory shock in children

The ongoing COVID-19 pandemic has cost hundreds of thousands of human lives, besides more than 11 million cases. Caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the disease was initially thought to be more severe in the elderly and those with pre-existing medical conditions. However, it started to manifest in children after the peak of the first wave.

7 Jul 2020

Faulty immune response to SARS-CoV-2 one of the main causes of death

A new study published on the preprint server medRxiv in July 2020 describes the organ and tissue-specific spread of the virus causing the current COVID-19 pandemic, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

7 Jul 2020

Chilblains and COVID-19

The current COVID-19 pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is primarily a respiratory infection, though the majority of cases are asymptomatic or mild disease. However, other manifestations are also being reported, such as gastrointestinal features, neurological signs, and skin symptoms. A new study published online in the journal JAMA Dermatology in June 2020 examines the possibility that chilblains could be a manifestation of COVID-19.

26 Jun 2020

A family with five doctors — and two COVID deaths

On the morning of April 1, Dr. Priya Khanna inched her way from the bedroom to the front door, using walls, doors and railings to hold herself up long enough to get to the stretcher waiting outside. She had been battling COVID-19 for five days and was struggling to breathe.

11 Jun 2020

Novel compound shows promise for ANCA-associated vasculitis

ANCA-associated vasculitis (AAV) is a systemic disease involving the formation of special autoantibodies (so-called anti-neutrophil cytoplasmic antibodies/ANCA) and vascular inflammation.

8 Jun 2020

COVID-19 can increase stroke risk in young healthy people

Young patients with no risk factors for stroke may have an increased risk if they have contracted COVID-19, whether or not they are showing symptoms of the disease.

4 Jun 2020

Kawasaki disease outbreak in children with COVID-19

The ongoing COVID-19 pandemic has marched its way to almost all parts of the world, with hundreds of thousands of deaths and over 4.5 million cases as of May 15, 2020. One saving grace has been the apparent sparing of children, though the mortality in older people is quite high.

17 May 2020

Global healthy living foundation launches autoimmune patient COVID-19 research project

Today the Global Healthy Living Foundation (GHLF) and CreakyJoints®, its digital patient community for people with all forms of arthritis, announced the launch of the Autoimmune COVID-19 Project.

24 Apr 2020

Scientists isolate individual cells that cause autoimmune disease

Researchers have homed in on the cells that cause an autoimmune disease to arise in the body. The study, published in the journal Cell in February 2020, as part of the far-seeing Hope Research project, reports on the discovery.

13 Feb 2020

Rheumatoid arthritis linked to other diseases, finds new study

A study found that risk of developing rheumatoid arthritis is higher in people with certain diseases.

21 Nov 2019

Study shows ADA2 is a sensitive, specific biomarker for macrophage activation syndrome

According to new research findings presented at the 2019 ACR/ARP Annual Meeting, adenosine deaminase 2 (ADA2) in the peripheral blood is a sensitive, specific biomarker for macrophage activation syndrome, a potentially life-threatening complication of systemic juvenile idiopathic arthritis (systemic JIA)

10 Nov 2019

Clinical trial to evaluate efficacy and safety of new treatment for giant cell arteritis

An international, multicenter phase II clinical trial is evaluating the efficacy and safety of mavrilimumab co-administered with a 26-week corticosteroid taper in patients with giant cell arteritis.

26 Sep 2019

Survey says half of people with rheumatoid disease struggle to pay for treatment

Rheumatoid disease encompasses inflammatory conditions that affect the joints, muscle, bones, and organs. A new study found that despite 90 of patients have health insurance, nearly 60 percent said that they are struggling to afford medication or treatment in the last year.

16 Sep 2019

Tiny fat bubbles hold key to rebooting the immune system and calming disease process

People living with inflammatory autoimmune disease could benefit from an 'immune system reboot', and researchers have isolated specific cells to target.

7 Sep 2019

Researchers identify encephalitis as rare toxicity of immunotherapy treatment

After a cancer patient receiving an immunotherapy developed encephalitis and died 18 months into treatment, researchers at Vanderbilt-Ingram Cancer Center investigated why the complication occurred, performing a molecular analysis of the disease's pathology and mining data to determine the incidence of similar occurrences.

22 Jul 2019

Promising methods for early detection and treatment of rheumatoid arthritis

Rheumatoid arthritis is a chronic inflammatory autoimmune disorder that leads to significant health issues as well as high treatment costs. In this themed issue of Clinical Therapeutics, published by Elsevier, experts review multiple aspects of RA detection and intervention with the overall goal of moving the field closer to developing effective preventive measures.

10 Jun 2019

Radiation-induced vascular damage could be treated with IL-1 inhibitors

Radiation therapy against cancer can increase the risk of cardiovascular disease much later in life, as the radiation causes chronic inflammation of the exposed blood vessels.

14 May 2019

Association found between gene variant and lung disease in the form of systemic vasculitis

University of Tsukuba-led team reveals the association between a gene variant and a lung disease in the form of systemic vasculitis particularly prevalent in the Japanese, potentially providing a target for future therapies.

13 Mar 2019