Weight Loss News and Research

Latest Weight Loss News and Research

Most patients regain lost weight within two years of stopping obesity drugs

Weight management medications show limited long-term effects, with rapid weight regain post-treatment, emphasizing the need for sustainable obesity strategies.

13 Jan 2026

Why some people can’t lose weight even when they follow the rules

New research reveals biological factors, not just effort, influence weight loss success, highlighting the need for personalized diet and exercise interventions.

13 Jan 2026

Why adherence determines weight loss success with semaglutide

Researchers examine how the effectiveness of weight-loss medications may depend on the patient adherence.

12 Jan 2026

Weight loss normalizes fat tissue at cellular level

It is well known that obesity typically leads to inflammation and dysfunction of fat tissue that increases the risk of developing metabolic diseases such as diabetes and cardiovascular diseases.

12 Jan 2026

Metabolic BMI reveals hidden health risks in normal weight individuals

People of normal weight may also be at risk of diabetes and similar diseases. A study from the University of Gothenburg reveals that those with an unexpectedly high so-called metabolic BMI have up to a five times higher risk level.

12 Jan 2026

Weight loss drugs and surgery improve body composition in patients with obesity

Both the new weight loss drugs and bariatric (weight loss) surgery improve body composition in patients with obesity by inducing a moderate loss of fat-free mass (including lean muscle) along with a substantial reduction in fat, researchers at Vanderbilt Health have found.

9 Jan 2026

George Mason trial: New pill aims to sustain weight loss after GLP-1s

GLP-1 medications like Ozempic and Wegovy have transformed obesity treatment, but maintaining weight loss after the medications stop remains a challenge.

9 Jan 2026

Self-administered injectable contraceptives face provider hesitancy despite availability

Self-administered injectable contraceptives have been available in the United States for more than two decades, yet a new study has found only about a quarter of reproductive health experts prescribe it - and many are unaware it's even an option.

9 Jan 2026

California ends Medicaid coverage of weight loss drugs despite TrumpRx plan

Many low-income Californians prescribed wildly popular weight loss drugs lost their coverage for the medications at the start of the new year.

9 Jan 2026

Why promising microbiome therapies rarely work in patients

Addressing the microbiome's translational gap involves understanding biological complexity and developing function-driven, patient-specific interventions.

8 Jan 2026

Study highlights prevalence of GLP-1/GIP medication use for weight loss in UK

In early 2025, around 4.9 million British adults - almost one in ten - are estimated to have recently used, or expressed interest in using, glucagon-like peptide-1 (GLP-1) or dual GLP-1/glucose-dependent insulinotropic polypeptide (GIP) receptor agonist medications to support weight loss. The findings, which are based on a nationally representative household survey of 5,260 British adults, are published in BMC Medicine.

8 Jan 2026

Weight loss drugs may cause nutritional deficiencies without proper guidance

People prescribed the new generation of weight loss drugs may not receive sufficient nutritional guidance to support safe and sustainable weight loss, leaving them vulnerable to nutritional deficiencies and muscle loss, say experts at UCL and the University of Cambridge.

7 Jan 2026

Millions in Great Britain using or seeking weight loss drugs

An estimated 1.6 million adults in England, Wales and Scotland used drugs such as Wegovy and Mounjaro to help lose weight between early 2024 and early 2025, according to a new study by UCL (University College London) researchers.

7 Jan 2026

Stopping weight loss drugs leads to rapid weight regain and health reversal

Stopping weight loss drugs is followed by weight regain and reversal of beneficial effects on heart and metabolic health markers such as high cholesterol and high blood pressure, finds a study published by The BMJ today.

7 Jan 2026

Pitavastatin shows pomise in overcoming chemotherapy resistance in triple-negative breast cancer

Triple-negative breast cancer (TNBC) is among the most aggressive types of breast cancer, lacking estrogen, progesterone, and HER2 receptors and thus relying primarily on cytotoxic chemotherapy.

7 Jan 2026

The gut is not just digestive and new evidence shows it actively controls brain function

This comprehensive review synthesizes a decade of human and animal research to explain how the gut and brain communicate through hormonal, neural, immune, and microbial pathways. It highlights how disruptions in these pathways contribute to gastrointestinal, metabolic, and neurological disorders, and how modern therapies are beginning to exploit gut–brain signaling for clinical benefit.

6 Jan 2026

Can ketogenic diets help PCOS? New analysis points to weight and insulin gains

A systematic review and meta-analysis of 15 studies found that ketogenic diets were associated with short-term reductions in body weight, waist circumference, insulin resistance, and some reproductive hormones in women with polycystic ovary syndrome, primarily among those with overweight or obesity. However, substantial heterogeneity, low certainty of evidence, limited safety reporting, and short follow-up periods mean the clinical effectiveness and long-term sustainability of ketogenic diets in PCOS remain uncertain.

5 Jan 2026