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Mechanisms of tissue shape transformation revealed through fruit fly wing development

A key question that remains in biology and biophysics is how three-dimensional tissue shapes emerge during animal development.

9 Aug 2024

New insights into retrotransposon-derived DNA zip codes in myeloma cells

A new editorial was published in Oncoscience (Volume 11) on July 13, 2024, entitled, "Unveiling retrotransposon-derived DNA zip code for myeloma cell internalization."

9 Aug 2024

Breakthrough in the synthesis of fungal bioactive compounds for therapeutic applications

The natural world is rich in chemical compounds with remarkable medicinal properties. A notable example is penicillin, discovered by chance from the Penicillium mold.

9 Aug 2024

Controllable chiral switching in double-helical foldamers for advanced molecular systems

The deoxyribonucleic acid or DNA, the molecular system that carries the genetic information of living organisms, can transcribe and amplify information using its two helical strands.

9 Aug 2024

DeepPBS: A geometric AI model for accurate prediction of protein-DNA binding specificity

A new artificial intelligence model developed by USC researchers and published in Nature Methods can predict how different proteins may bind to DNA with accuracy across different types of protein, a technological advance that promises to reduce the time required to develop new drugs and other medical treatments.

9 Aug 2024

Machine learning revolutionizes gene delivery

Gene therapy could potentially cure genetic diseases but it remains a challenge to package and deliver new genes to specific cells safely and effectively. Existing methods of engineering one of the most commonly used gene-delivery vehicles, adeno-associated viruses (AAV), are often slow and inefficient.

9 Aug 2024

Lensless fluorescence detection system provides highly sensitive water quality assessment

Researchers have shown that a fluorescence detection system that doesn't contain any lenses can provide highly sensitive detection of deadly microorganisms in drinking water. With further development, the new approach could provide a low-cost and easy-to-use way to monitor water quality in resource-limited settings such as developing countries or areas affected by disasters. It could also be useful when water safety results are needed quickly, such as for swimming events, a concern highlighted during the Paris Olympics.

9 Aug 2024

Breakthrough study uncovers TIP60’s role in DNA access and disease mechanisms

To transcribe the information contained in our genes or to repair the dozens of breaks that occur daily in our DNA, our enzymes must be able to directly access the DNA to perform their functions.

9 Aug 2024

Autism and ADHD linked to neighborhood conditions

Autistic youth who were born in underserved neighborhoods are more likely to have greater attention deficit hyperactivity disorder (ADHD) symptoms than those born in communities with more resources. This is one finding of a new study led by researchers at the UC Davis MIND Institute.

9 Aug 2024

Columbia study reveals bacteria create free-floating genes, challenging genetic code norms

Since the genetic code was first deciphered in the 1960s, our genes seemed like an open book. By reading and decoding our chromosomes as linear strings of letters, like sentences in a novel, we can identify the genes in our genome and learn why changes in a gene's code affect health.

9 Aug 2024

New insights into topoisomerase I inhibition reveal potential pathways for cancer therapies

A research group at the University of Bologna has identified, for the first time, the specific location and genomic context where DNA breaks occur due to the inhibition of the topoisomerase I, a protein crucial for many biological processes in cells.

8 Aug 2024

Breakthrough discovery could boost stem-cell transplants by improving cell mobilization

A discovery by a three-member Albert Einstein College of Medicine research team may boost the effectiveness of stem-cell transplants, commonly used for patients with cancer, blood disorders, or autoimmune diseases caused by defective stem cells, which produce all the body's different blood cells.

8 Aug 2024

ProDOL revolutionizes protein quantification in living cells

Scientists have developed a new way of counting labeled proteins in living cells that could become a standard and valuable tool in the field of biomedical research.

8 Aug 2024

Navigating the future of drug development at the C-Path Global Impact Conference

Critical Path Institute (C-Path), whose mission is to lead collaborations that accelerate drug development, advancing better treatments for people worldwide, is proud to announce its inaugural C-Path Global Impact Conference (CGIC), taking place from September 9-11, 2024, at the Washington Marriott at Metro Center.

8 Aug 2024

How C. elegans uses smell to preemptively guard against pathogen attacks

Many organisms react to the smell of deadly pathogens by reflexively avoiding them. But a recent study from the University of California, Berkeley, shows that the nematode C. elegans also reacts to the odor of pathogenic bacteria by preparing its intestinal cells to withstand a potential onslaught.

7 Aug 2024

Life Science News

Mechanisms of tissue shape transformation revealed through fruit fly wing development

New insights into retrotransposon-derived DNA zip codes in myeloma cells

Breakthrough in the synthesis of fungal bioactive compounds for therapeutic applications

Controllable chiral switching in double-helical foldamers for advanced molecular systems

DeepPBS: A geometric AI model for accurate prediction of protein-DNA binding specificity

Machine learning revolutionizes gene delivery

Lensless fluorescence detection system provides highly sensitive water quality assessment

Breakthrough study uncovers TIP60’s role in DNA access and disease mechanisms

Autism and ADHD linked to neighborhood conditions

Columbia study reveals bacteria create free-floating genes, challenging genetic code norms

New insights into topoisomerase I inhibition reveal potential pathways for cancer therapies

Breakthrough discovery could boost stem-cell transplants by improving cell mobilization

ProDOL revolutionizes protein quantification in living cells

Navigating the future of drug development at the C-Path Global Impact Conference

How C. elegans uses smell to preemptively guard against pathogen attacks

New treatment boosts pluripotent stem cell production in mice

Study reveals key brain cells help resist food temptations in favor of exercise

Breakthrough study highlights ATM activation by DNA single-strand breaks

Social genomics: How friends' genes impact a person's mental health

Ribosomes in cells play a crucial role in protein folding

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

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