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NIH grant to fund development of new gene therapy platform for brain diseases

A two-phase NIH grant will fund research into a new CRISPR-based gene therapy platform that will target genetic brain diseases like Angelman syndrome and H1-4 (HIST1H1E) syndrome.

3 Oct 2023

Genetic testing of one thousand embryos provides insights into human development and IVF

By genetically testing nearly one thousand embryos, scientists have provided the most detailed analysis of embryo fate following human in vitro fertilization.

3 Oct 2023

A better method to predict polygenic inheritance across multiple ancestries

Researchers report the results obtained from the use of a new PRS calculator called CT-SLEB on a multi-national GWAS database.

2 Oct 2023

Unlocking hope for mitochondrial disorders with INTEGRA Biosciences’ electronic pipette

INTEGRA Biosciences’ VOYAGER adjustable tip spacing pipette to support their research on mitochondrial diseases.

From INTEGRA Biosciences 2 Oct 2023

Start Codon invites life sciences leaders, founders, and investors to Innovation Showcase 2023

Start Codon is pleased to invite life sciences people from across the life science and biotech industries to attend their Innovation Showcase 2023.

From Start Codon Ltd 2 Oct 2023

Broken String Biosciences strengthens senior leadership team to accelerate product development and commercialization

Broken String Biosciences, a genomics company building a technology platform to drive the development of cell and gene therapies that are safer by design, today announced the expansion of its senior leadership team.

From Broken String Biosciences 2 Oct 2023

Killer T cells in older adults found to be less effective at fighting influenza viruses

A world-first discovery has revealed special immune cells called ‘killer T cells’ in older adults, directed against influenza viruses, closely resemble those found in newborns and children, but struggle to recognise infected cells – a finding that unlocks the potential for the development of better vaccines and therapies tailored to different age groups.

30 Sep 2023

New CRISPR-based gene-editing tool could lead to better treatments for genetic disorders

A new CRISPR-based gene-editing tool has been developed which could lead to better treatments for patients with genetic disorders.

29 Sep 2023

Study shows how tumors "hijack" genetic program used by developing nerves

Cancer tumors "hijack" the genetic program used by developing nerves. This is shown in a study by researchers at Umeå University, Sweden.

29 Sep 2023

New protein identified as substrate for histidine methylation

Proteins are subject to post-translational chemical modifications that result in functional diversity. Methylation is one such modification that is generally believed to occur on lysine and arginine residues.

29 Sep 2023

Monocyte-derived macrophages play a crucial role in liver regeneration

The liver is a vital organ that plays a role in many essential functions, including digestion, detoxification, and metabolism.

29 Sep 2023

New toolbox solves 50-year-old blood group mystery

Currently, a lot is known about which genes are responsible for our individual blood groups, however not much is understood about how and why the levels of the blood group molecules differ between one person and another.

29 Sep 2023

Cutting-edge NanoSIMS imaging sheds light on the progression of Parkinson's disease

Parkinson's disease is a complex neurodegenerative disorder that leads to the deterioration of specific types of neurons in the brain, resulting in a number of motor and non-motor symptoms.

29 Sep 2023

New research reveals how social isolation impacts behavior and lifespan in social species

Researchers used Camponotus fellah (carpenter ants) as a model species to perform behavioral tracking and ribonucleic acid-sequencing (RNA-seq) to study the transcriptome-level differences between socially isolated workers versus workers in groups.

29 Sep 2023

Study reveals how DNA damage caused by chromosomal instability increases cancer invasiveness

Chromosomal instability is a phenomenon characterized by rapid changes in the number and structure of chromosomes during cell division.

28 Sep 2023

Unlocking the code: BigRNA's deep learning model predicts RNA behavior

Researchers have developed BigRNA, a groundbreaking deep learning model capable of predicting RNA behavior, including tissue-specific expression and splicing, directly from genomic DNA sequences. The model excels in identifying pathogenic variants and could be a game-changer in the development of personalized RNA-based therapies for treating genetic diseases.

28 Sep 2023

Researchers describe the origin and fate of liver myofibroblasts

Hepatic fibrosis occurs when scar tissue replaces damaged cells in the liver. Over time, accumulating scarring distorts the liver, interferes with its blood supply and may progressively lead to worsening consequences, from cirrhosis to liver failure to liver cancer.

28 Sep 2023

New framework for ethical microbiome research practices that include Indigenous communities

Every person hosts trillions of microorganisms, like bacteria and viruses, on their skin and in organs including those that make up the digestive tract, like their mouth, that collectively make up their microbiome.

28 Sep 2023

Double-layer polysaccharide hydrogel overcomes challenges of probiotic delivery

In a groundbreaking study, a research team led by Changhu Xue and Xiangzhao Mao from the Ocean University of China has developed a remarkable double-layer polysaccharide hydrogel (DPH) that promises to revolutionize the field of intestine-targeted oral delivery of probiotics.

28 Sep 2023

Bioengineered human stomach micro-physiological system reveals unseen defense mechanisms

A groundbreaking development in biomedical engineering has led to the creation of a human stomach micro-physiological system (hsMPS), representing a significant leap forward in understanding and treating various gastrointestinal diseases, including stomach cancer.

28 Sep 2023

Life Science News

NIH grant to fund development of new gene therapy platform for brain diseases

Genetic testing of one thousand embryos provides insights into human development and IVF

A better method to predict polygenic inheritance across multiple ancestries

Unlocking hope for mitochondrial disorders with INTEGRA Biosciences’ electronic pipette

Start Codon invites life sciences leaders, founders, and investors to Innovation Showcase 2023

Broken String Biosciences strengthens senior leadership team to accelerate product development and commercialization

Killer T cells in older adults found to be less effective at fighting influenza viruses

New CRISPR-based gene-editing tool could lead to better treatments for genetic disorders

Study shows how tumors "hijack" genetic program used by developing nerves

New protein identified as substrate for histidine methylation

Monocyte-derived macrophages play a crucial role in liver regeneration

New toolbox solves 50-year-old blood group mystery

Cutting-edge NanoSIMS imaging sheds light on the progression of Parkinson's disease

New research reveals how social isolation impacts behavior and lifespan in social species

Study reveals how DNA damage caused by chromosomal instability increases cancer invasiveness

Unlocking the code: BigRNA's deep learning model predicts RNA behavior

Researchers describe the origin and fate of liver myofibroblasts

New framework for ethical microbiome research practices that include Indigenous communities

Double-layer polysaccharide hydrogel overcomes challenges of probiotic delivery

Bioengineered human stomach micro-physiological system reveals unseen defense mechanisms

Edoardo Fabini

Reducing polypharmacy through innovative drug formulation technologies

How innovation in dried blood spot testing is transforming neurological disease monitoring

Latest Life Science News