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Bioorthogonal system for targeted release of nitrite ions into cancer cells

A team of researchers writing in the journal Angewandte Chemie has developed a bioorthogonal molecular system for the targeted introduction of nitrite ions into cells.

30 Nov 2022

Upcycling polyethylene waste into pharmacologically useful natural products

Plastic waste is one of the most significant ecological and economic problems of our time. In the journal Angewandte Chemie, a research team has now introduced a chemical–biological method for upcycling polyethylene waste: catalytic cleavage is used to make carboxylic diacids that are subsequently converted into pharmacologically useful natural products by genetically engineered fungi.

30 Nov 2022

Aptamer Group opens new facilities to meet the increasing demand for Optimer technology

Aptamer Group plc, the developer of novel Optimer® binders to enable innovation in the life sciences industry, announces that it has opened its new facilities in York Science Park, UK, that will enable it to meet the increasing demand for Optimer technology.

From Aptamer Group 30 Nov 2022

CSU engineers introduce a better way to perform mosquito-tracking for disease applications

West Nile, Zika, dengue and malaria are all diseases spread by bites from infected mosquitoes. To track the threat of such diseases over large populations, scientists need to know where the mosquitoes are, where they've been, and where they might go.

30 Nov 2022

Lysis and hypotonic sonication buffers for ChIP assays

Offering complete disruption of cytoplasmic and nuclear membranes, Porvair Sciences Chromatrap® buffer chemistries are optimised for sonication and enzymatic shearing.

From Porvair Sciences Limited 29 Nov 2022

Understanding the genetics of healthy brain cells to target vulnerabilities in glioblastomas

Understanding how cancer cells evolve from healthy brain cells and evade treatment could open up potential new drug therapies for glioblastomas, one of the most common and lethal brain cancers, new research has revealed.

29 Nov 2022

Powerful imaging tool creates 3D atlas of the spectrum of tuberculous and COVID-19 lung lesions

Gross anatomy reveals three-dimensional shapes of pathology at a large scale. Histology, in contrast, reveals the microscopic anatomy of biological structures. But that magnification comes at a cost -; histology shows only two-dimensional shapes because it studies small, flat slices of stained tissue.

29 Nov 2022

Study links MAIT cells to cognitive function

Could the underproduction of poorly understood immune cells contribute to Alzheimer's disease and other forms of cognitive decline? A Rutgers study in Nature Immunology suggests it may – and that increasing these cells could reverse the damage.

29 Nov 2022

Activation of microglial cells can slow down Alzheimer's progression

The brain's big-eating immune cells can slow down the progression of Alzheimer's disease. This is shown by a study that is now published in Nature Aging.

29 Nov 2022

How SARS-CoV-2 immune responses vary by population due to environmental and genetic factors

Researchers investigate the genetic, immunological, and evolutionary factors that determine the vast variability observed in clinical manifestations of COVID-19.

28 Nov 2022

UCSC engineers develop new method to automate the growth of cerebral organoids

A team of engineers at UC Santa Cruz has developed a new method for remote automation of the growth of cerebral organoids – miniature, three-dimensional models of brain tissue grown from stem cells.

28 Nov 2022

New computer-based platform could make drug discovery process more efficient and less expensive

Researchers at The University of Texas at Dallas and Novartis Pharmaceuticals Corp. have devised a computer-based platform for drug discovery that could make the process more effective, more efficient and less costly.

28 Nov 2022

Imaging brain activity deep in the cortex of freely moving mouse

How does the brain produce behavior? Studying the brain during behavior is most informative when the animal is free to interact with its environment in any way it chooses.

28 Nov 2022

New microfluidic Organ Chip platform replicates the human vaginal tissue microenvironment

The human microbiome has been a hot topic over the last decade, with research pointing to disrupted bacterial communities as culprits for a host of maladies including irritable bowel syndrome, eczema, and autoimmune diseases.

28 Nov 2022

Rogue killer T cells associated with leukemia drive autoimmune diseases

Gene variants associated with leukemia can produce 'rogue' immune cells that drive autoimmune diseases, according to a new study from the Garvan Institute of Medical Research.

28 Nov 2022

Researchers uncovers a link between D-amino acids and severe viral infection

Just as bricks are key components in constructing a building, molecules known as amino acids are essential components in constructing proteins in the body.

28 Nov 2022

Using human iPSC-derived cells to revolutionize the field of neurodegenerative disease

In this interview, we speak to Axol Bioscience about their human iPSC-derived cells and how they have the potential to revolutionize the field of neurodegenerative disease.

From Axol Bioscience Ltd 28 Nov 2022

New chemical probe can selectively inhibit human COQ8A protein in cells

Inhibition of the COQ8 protein could be beneficial in the treatment of diseases such as cancer. COQ8 is needed for the biosynthesis of coenzyme Q, also known as ubiquinone.

28 Nov 2022

Nanoparticles displaying SARS-CoV-1 and SARS-CoV-2 spikes induce broad antibody responses in animal model

A recent study published in the journal iScience reported that nanoparticles (NPs) co-displaying spike proteins from different sarbecoviruses improve the breadth of neutralizing responses.

27 Nov 2022

MicroRNAs play a key role in the development of complex brains

Cephalopods like octopuses, squids and cuttlefish are highly intelligent animals with complex nervous systems.

25 Nov 2022

Life Science News

Bioorthogonal system for targeted release of nitrite ions into cancer cells

Upcycling polyethylene waste into pharmacologically useful natural products

Aptamer Group opens new facilities to meet the increasing demand for Optimer technology

CSU engineers introduce a better way to perform mosquito-tracking for disease applications

Lysis and hypotonic sonication buffers for ChIP assays

Understanding the genetics of healthy brain cells to target vulnerabilities in glioblastomas

Powerful imaging tool creates 3D atlas of the spectrum of tuberculous and COVID-19 lung lesions

Study links MAIT cells to cognitive function

Activation of microglial cells can slow down Alzheimer's progression

How SARS-CoV-2 immune responses vary by population due to environmental and genetic factors

UCSC engineers develop new method to automate the growth of cerebral organoids

New computer-based platform could make drug discovery process more efficient and less expensive

Imaging brain activity deep in the cortex of freely moving mouse

New microfluidic Organ Chip platform replicates the human vaginal tissue microenvironment

Rogue killer T cells associated with leukemia drive autoimmune diseases

Researchers uncovers a link between D-amino acids and severe viral infection

Using human iPSC-derived cells to revolutionize the field of neurodegenerative disease

New chemical probe can selectively inhibit human COQ8A protein in cells

Nanoparticles displaying SARS-CoV-1 and SARS-CoV-2 spikes induce broad antibody responses in animal model

MicroRNAs play a key role in the development of complex brains

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Latest Life Science News