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AI-designed drug candidate shows promise for gastric acid inhibition

Researchers at Nagoya University in Japan created and improved artificial intelligence (AI) designs to synthesize a candidate compound for a new gastric acid inhibitor with a better binding affinity than existing drugs.

26 Oct 2023

Study shows phages can promote mammalian cellular growth and survival

Bacteriophages, also called phages, are viruses that infect and kill bacteria, their natural hosts. But from a macromolecular viewpoint, phages can be viewed as nutritionally enriched packets of nucleotides wrapped in an amino acid shell.

26 Oct 2023

Is retroelement-based gene editing a safer alternative to CRISPR-Cas approaches?

In a Perspective, Stephen Tang and Samuel Sternberg discuss retroelement-based gene editing as a safer alternative to CRISPR-Cas approaches.

26 Oct 2023

Fungi used to produce food products have potential probiotic effects on gut inflammation

Many fungus strains have been used and selected by the food industry for their capacities to ferment, produce flavors or produce heterologous molecules.

26 Oct 2023

UCD professor wins ERC Synergy grant to unlock the secrets to healthy aging

Do bats hold the secret to health and longevity? A team led by Professor Emma Teeling, Full Professor of Zoology at University College Dublin (UCD), has won a prestigious European Research Council (ERC) Synergy grant of almost €12 million, to explore this fascinating question.

26 Oct 2023

Endometriosis and irritable bowel syndrome share genetic risk factors, UQ research shows

University of Queensland researchers have shown that endometriosis and irritable bowel syndrome (IBS) share genetic risk factors, explaining why patients with one condition may also have the other.

26 Oct 2023

Somatic mutations in the skin not responsible for the start or spread of psoriasis

Psoriasis - a chronic skin condition - is not caused or spread by spontaneous genetic mutations in the skin, new research suggests.

26 Oct 2023

Newly identified amino acid may play key role in predicting outcomes and treatment of long COVID

University of Alberta researchers have identified an amino acid that may play a key role in predicting poor clinical outcomes and the treatment of long COVID.

26 Oct 2023

New bioreactor could accelerate access to cancer-killing immunotherapy

A new tool to rapidly grow cancer-killing white blood cells could advance the availability of immunotherapy, a promising therapy which harnesses the power of the body's immune response to target cancer cells.

26 Oct 2023

New Sartorius Digital Handbook brings the power of High-Throughput Screening (HTS) by cytometry to every scientist

Sartorius, an industry-leading innovator of advanced instruments for cell analysis has released its first Advanced Flow Cytometry Handbook as a comprehensive digital guide to assays and workflows on the iQue® Advanced High Throughput Flow Cytometry Platform.

From Sartorius 26 Oct 2023

Stanford chemists uncover new pathway for protein degradation, opening door to new therapeutics

When targeting problem proteins involved in causing or spreading disease, a drug will often clog up a protein's active site so it can't function and wreak havoc.

25 Oct 2023

How strep bacteria outsmart your immune system and why it matters for treatment

Researchers discover that Group A streptococcal infections alter immunoglobulin G (IgG) homeostasis to evade the immune system, affecting the transition from local to systemic infections. The study also raises concerns about the effectiveness of antibody-based therapies, as the bacteria's virulence factors can degrade therapeutic antibodies.

25 Oct 2023

Scientists discover hidden intricacies of sperm motility

Researchers at Stockholm University have unveiled the hidden intricacies of how sperm go from passive bystanders to dynamic swimmers.

25 Oct 2023

New biomaterial could change the way human tissue can be grown in the lab

Scientists at UNSW Sydney have created a new material that could change the way human tissue can be grown in the lab and used in medical procedures.

24 Oct 2023

New software tool provides a way for safer design of genome editing

A team of researchers has developed a software tool called DANGER (Deleterious and ANticipatable Guides Evaluated by RNA-sequencing) analysis that provides a way for the safer design of genome editing in all organisms with a transcriptome.

24 Oct 2023

Could the microbiome hold the key to diagnosing and treating biliary tract cancer?

A recent study in "Microorganisms" delves into the relationship between the microbiome and biliary tract cancer, revealing distinct microbial compositions in patients compared to healthy individuals. This research highlights potential diagnostic biomarkers and suggests that altering gut microbial composition might enhance responses to cancer immunotherapy.

24 Oct 2023

Gene therapy breakthrough: Scientists develop method to deliver larger genes to target cells

Gene therapy currently represents the most promising approach for the treatment of hereditary diseases. Yet despite significant breakthroughs in recent years, there are still a number of hurdles that hinder the wider application of gene therapies.

24 Oct 2023

Plant microorganisms from fruit and vegetables boost gut diversity

Bacterial diversity in the gut plays an important role in human health. The crucial question, however, is where are the sources of this diversity? It is known that an important part of the maternal microbiome is transferred to the baby at birth, and the same happens during the breastfeeding period via breast milk.

24 Oct 2023

Researchers discover new way to trigger programmed cell death in cancer cells

A research team from the UC Davis Comprehensive Cancer Center has identified a crucial epitope (a protein section that can activate the larger protein) on the CD95 receptor that can cause cells to die.

24 Oct 2023

Study reveals an alternate origin of brain mosaicism in some children with focal epilepsy

In most people, every cell in their body contains the same genetic information. However, sometimes people can have two or more genetically different sets of cells.

24 Oct 2023

Life Science News

AI-designed drug candidate shows promise for gastric acid inhibition

Study shows phages can promote mammalian cellular growth and survival

Is retroelement-based gene editing a safer alternative to CRISPR-Cas approaches?

Fungi used to produce food products have potential probiotic effects on gut inflammation

UCD professor wins ERC Synergy grant to unlock the secrets to healthy aging

Endometriosis and irritable bowel syndrome share genetic risk factors, UQ research shows

Somatic mutations in the skin not responsible for the start or spread of psoriasis

Newly identified amino acid may play key role in predicting outcomes and treatment of long COVID

New bioreactor could accelerate access to cancer-killing immunotherapy

New Sartorius Digital Handbook brings the power of High-Throughput Screening (HTS) by cytometry to every scientist

Stanford chemists uncover new pathway for protein degradation, opening door to new therapeutics

How strep bacteria outsmart your immune system and why it matters for treatment

Scientists discover hidden intricacies of sperm motility

New biomaterial could change the way human tissue can be grown in the lab

New software tool provides a way for safer design of genome editing

Could the microbiome hold the key to diagnosing and treating biliary tract cancer?

Gene therapy breakthrough: Scientists develop method to deliver larger genes to target cells

Plant microorganisms from fruit and vegetables boost gut diversity

Researchers discover new way to trigger programmed cell death in cancer cells

Study reveals an alternate origin of brain mosaicism in some children with focal epilepsy

How innovation in dried blood spot testing is transforming neurological disease monitoring

Unlocking live single-cell functional insights

How microRNA is transforming science: From discovery to diagnostics

Latest Life Science News