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A large library of products derived from fungi could help find new drugs

An enormous library of products derived from more than ten thousand fungi could help us find new drugs.

26 Nov 2019

Enzyme caspase-8 controls apoptosis, necroptosis and pyroptosis

The enzyme caspase-8 induces a molecular cell death programme called pyroptosis without involving its enzymatic activity, a new study by Hamid Kashkar published in Nature shows.

26 Nov 2019

Air pollution associated with increased risk of deaths in Canada

Air pollution - even at levels below national and international air quality guidelines - is associated with an increased risk of deaths in Canada, according to new UBC research.

25 Nov 2019

Discovery in C. difficile biology opens new window to developing treatments for dangerous infections

A process called sporulation that helps the dangerous bacterium Clostridium difficile (C. difficile) to survive inhospitable conditions and spread is regulated by epigenetics, factors that affect gene expression beyond the DNA genetic code, researchers at the Icahn School of Medicine at Mount Sinai report.

25 Nov 2019

Research shows how cilia and exocyst contribute to extracellular vesicle production

Although the cilium has been known to scientists for more than 100 years, it is only recently that it has been acknowledged to play important roles in physiology.

25 Nov 2019

Article reveals new mechanism of programmed aging

Nature has sentenced humans to an inevitable death from the time of birth; the natural instrument of execution is the aging process. According to modern scientific notions, only two root causes of aging can be: stochastic physiological damage or the implementation of a special genetic program in the body.

25 Nov 2019

Fetuses may be able to see more than previously believed

By the second trimester, long before a baby's eyes can see images, they can detect light.

25 Nov 2019

New partnership aims to explore, cultivate innovations in cell and gene therapy

Some patients who have not responded to traditional medicines are now experiencing remarkable recoveries thanks to next-generation immunotherapies. These therapies equip a patient's own immune cells to recognize, target, and destroy cancer cells.

25 Nov 2019

New highly sensitive test for dengue virus developed using DNA star

Researchers have developed a new method for detecting and destroying the dengue virus that could be adapted for other viruses.

25 Nov 2019

Scientists record assembly of ribosomes in real time

A team of scientists from Scripps Research and Stanford University has recorded in real time a key step in the assembly of ribosomes--the complex and evolutionarily ancient "molecular machines" that make proteins in cells and are essential for all life forms.

22 Nov 2019

DNA-modulated liquid droplets may explain how prion proteins clump

Researchers at the Federal University of Rio de Janeiro, in Brazil, have identified that the interaction between prion proteins and DNA may be behind the formation of protein amyloid aggregates and of the emergence of neurodegenerative diseases such as Creutzfeldt-Jakob disease and other spongiform encephalopathies.

22 Nov 2019

Scientists investigate the dynamics of molecular changes in gliomas

Until relatively recently, cancer was viewed as a single disease with sub-types based on where in the body it arose.

22 Nov 2019

Wound healing events in mucous tissues could guard against AIDS

Wound healing events in mucous tissues during early infection by Simian Immunodeficiency Virus, or SIV, guard some primate species against developing AIDS, a recent study has learned.

21 Nov 2019

Extra DNA scooped up alongside cancer-causing genes helps drive tumor growth

One of the ways a cancer-causing gene works up enough power to turn a normal cell into a cancer cell is by copying itself over and over, like a Xerox machine.

21 Nov 2019

Doughnut-shaped circles of ecDNA provide tumor cells with a malignant twist

Deoxyribonucleic acid or DNA encodes information, not only in its sequence but also in its shape.

21 Nov 2019

Researchers develop breakthrough in marine sponge cell culture

Vertebrate, insect, and plant cell lines are important tools for research in many disciplines, including human health, evolutionary and developmental biology, agriculture and toxicology. Cell lines have been established for many organisms, including freshwater and terrestrial invertebrates.

21 Nov 2019

Neuroscientists decode how visual cues can reorganize the activity of compass neurons

If you've ever woken up in the middle of the night to go to the bathroom and stumbled around in the dark, banging into walls or dressers in a room you've walked through countless times, you've experienced the effects of inadequately calibrated neurons.

21 Nov 2019