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Researchers develop new molecular tool to decode sugar-protein attachments

Researchers at Johns Hopkins Medicine have developed a new molecular tool they call EXoO, which decodes where on proteins specific sugars are attached--a possible modification due to disease.

6 Dec 2018

INTEGRA's VIAFLO 96 helps improve reproducibility of high content screening

The VIAFLO 96 electronic multi-channel pipetting system is helping HCS Pharma to improve the reproducibility of high content screening.

From INTEGRA Biosciences 6 Dec 2018

New way to trace the transmission histories of rare genetic diseases

There are only 25 people in the whole of Quebec at the moment who have a rare recessive genetic disease called chronic atrial and intestinal dysrhythmia. Now, scientists have begun tracing the origins of these diseases.

6 Dec 2018

Researchers identify new type of T cell that could play role in cancer, other diseases

Researchers from the UCLA Jonsson Comprehensive Cancer Center and the La Jolla Institute for Immunology have identified a new type of T cell called a phospholipid-reactive T cell that is able to recognize phospholipids, the molecules that help form cells' outer membranes.

6 Dec 2018

Elevated hormone flags liver disease in mice with serious genomic disorder

Researchers have discovered that a hormone, fibroblast growth factor 21 (FGF21), is extremely elevated in mice with liver disease that mimics the same condition in patients with methylmalonic acidemia (MMA), a serious genomic disorder.

6 Dec 2018

Subset of immune B cells delays onset of type 1 diabetes in animal model

Researchers have conducted a study showing that a specific subset of immune B cells delays the onset of type 1 diabetes in mice.

6 Dec 2018

Jawless fish study provides a new story for inner ear evolution

Researchers at the RIKEN Center for Biosystems Dynamics (BDR) and collaborators have described for the first time the development of the hagfish inner ear. Published in the journal Nature, the study provides a new story for inner ear evolution that began with the last common ancestor of modern vertebrates.

6 Dec 2018

Researchers achieve breakthrough in blood vessel engineering

When someone has a deadly disease or sustains a life-threatening injury, a transplant or graft of new tissue may be the best -- or only -- treatment option.

6 Dec 2018

Researchers create new light-activated tools for controlling neurons

By enabling super-fast remote control of specific cells, light-activated proteins allow researchers to study the function of individual neurons within a large network - even an entire brain. Now one of the pioneers of 'optogenetics' and colleagues have created two new tools - protein pores which when illuminated allow Ca2+ into cells or K+ out - for switching neurons on or off using light.

6 Dec 2018

Scientists identify new drug target for potential blood pressure treatment

Scientists have identified a key player in blood pressure regulation and have shown that switching it off reduces blood pressure in mice, according to new research in eLife.

6 Dec 2018

New massive sequencing platform implemented for double factor preimplantation genetic testing

A research team from the Universitat Autònoma de Barcelona, in collaboration with the Blood and Tissue Bank of Catalonia, has managed to implement a massive sequencing platform for Preimplantation Genetic Testing for the first time in history.

5 Dec 2018

Functional ultrasound imaging can reveal brain activity maps of mice for specific behaviors

In a study published in Neuron, Emilie Macé from Botond Roska's group and collaborators demonstrate how functional ultrasound imaging can yield high-resolution, brain-wide activity maps of mice for specific behaviors.

5 Dec 2018

Scientists reveal how DNA damage leads to cancer and hereditary diseases

Scientists revealed how DNA damage influences mutations. Turned out that its contribution to mutagenesis was underestimated and many of the inheritance mutations are caused not by errors in DNA doubling, but by damage to this fragile molecule.

5 Dec 2018

Researchers find evidence of epigenetics in single-celled archaea

Researchers have found evidence of epigenetics-based evolution in a species of archaea, our oldest single-cell ancestors.

5 Dec 2018

Researchers take a step forward with a study of molecules of DNA

Researchers from the Andalusian center for Molecular Biology and regenerative Medicine and from the University of Seville have taken a step forward with a study of something as essential for life as the molecules of DNA.

5 Dec 2018

From Our Bench to Yours: Antibody Advice from Proteintech

An interview with Dr. Karolina Szczesna, discussing the tell-tale signs of a good antibody and how Proteintech are working to improve experimental results for scientists.

From Proteintech Group, Inc 5 Dec 2018

Ethnicity can be reliable indicator of gut microbiota diversity

Research increasingly links the gut microbiome to a range of human maladies, including inflammatory bowel disease, diabetes and even cancer. Attempts to manipulate the gut with food rich in healthy bacteria, such as yogurt or kombucha, are in vogue, along with buying commercial probiotics that promise to improve users' chances against illness.

4 Dec 2018

Selective survival of embryos under adverse conditions may explain health problems later in life

An international team led by researchers of the Leiden University Medical Center and Lund University in Sweden propose that selection of random epigenetic differences causes particular embryos to survive under adverse conditions in the womb.

4 Dec 2018

Eliminating microglia can reverse some aspects of stress sensitization, study shows

Using an animal model of chronic stress, researchers at The Ohio State University have shown that the immune cells of the brain, called microglia, hold unique signatures of chronic stress that leave the animal more sensitive to future stressful experiences, evident by increased anxiety and immune responses.

4 Dec 2018