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Cloning-free Nested CRISPR uses long DNA fragments for efficient gene editing

CRISPR is a technique that is revolutionizing biomedical research through high-precision genome editing. However, even though it allows the creation or correction of mutations consisting of a single or few nucleotides with relative ease, it still possesses limitations upon introducing larger fragments of DNA in the genome.

8 Feb 2019

New research on viral biology could lead to efficient vaccines against leishmaniasis

New research from McGill University has found that a virus infecting the Leishmania parasite spreads by exploiting a mechanism used for cell-to-cell communication, a discovery that could pave the way to new vaccines against infections that cause severe disfiguration.

8 Feb 2019

Mutations in folliculin gene affect embryo implantation

New information is unfolding on the genetic controls of an early turning point in pregnancy. As the tiny, dividing cell mass, the blastocyst, travels from the oviduct and lodges in the wall of the uterus, the cells must exit their pre-implantation state and be ready for post-implantation development.

7 Feb 2019

Insufficient sleep mirrored by DNA from blood leukocytes

An insufficient amount of sleep and qualitatively poor sleep are common among the general population. Prior studies have indicated that prolonged insufficient sleep and poor sleep quality are associated with a heightened risk of cardiovascular diseases, dementia and psychiatric disorders, particularly depression, yet the molecular mechanisms underlying this connection are not well known.

7 Feb 2019

LABVOLUTION: A digitized lab environment to be showcased at smartLAB 2019

In 2019, networking and interaction between people, machines and systems will be the primary focus of the smartLAB showcase. For the third time in succession, this project will pose the vision of leading-edge networked laboratories that incorporate new technology, thereby extending their range of capabilities.

From LABVOLUTION 7 Feb 2019

Detecting and mapping of chemicals inside a biological cell

How are chemicals distributed in a cell? Chinese scientists have developed a combined mass spectrometry and biological imaging device that enables direct, label-free detection, and high-resolution mapping of chemicals inside a biological cell.

7 Feb 2019

Scientists untangle how microbes manufacture key antibiotic compound

For decades, scientists and doctors have known that bacteria in soil were capable of manufacturing streptozotocin, an antibiotic compound that is also an important treatment for certain types of pancreatic cancer.

7 Feb 2019

New discovery can explain resistance of cancer types to fatty acid metabolism inhibition

Fatty acid metabolism is an essential process in tumor growth and proliferation. Despite different attempts to block fatty acid metabolism as a therapeutic strategy to reduce tumor size and growth, the outcome was not always positive.

7 Feb 2019

New 'WormJam model' could provide valuable insights into human aging

What can worms tell us about human aging? A lot more than you'd think; as research led by the Babraham Institute but involving researchers from multiple disciplines drawn together from across the world has shown.

7 Feb 2019

Researchers understand cues controlling collective cell migration during development

Collective cell migration, where groups of cells move together with a common purpose, is important for processes ranging from wound healing to tumor metastasis.

6 Feb 2019

Rare stem cell may be the root of all metastatic cancers

Researchers have discovered a rogue stem cell that could be the cause of all metastatic cancers. The breakthrough could affect all future research projects.

6 Feb 2019

Improving sustainability of industrial laundry

Syrris provides award-winning chemistry products to a range of research and development chemists and engineers, including Xeros Technology Group, a company specializing in novel and sustainable polymer solutions to advance the commercial laundry industry.

From Syrris Ltd 6 Feb 2019

Making the Most of Microdialysis for Neurotransmitter Analysis

Martin Eysberg provides an introduction to the ALEXYS Neurotransmitter Analyzer, an extremely precise UHPLC-EC detector for neurotransmitter analysis.

From Antec Scientific 6 Feb 2019

Bruker launches new SKYSCAN 1273 benchtop 3D X-ray microscope

Bruker today announced the new SKYSCAN 1273 benchtop 3D X-ray microscope based on micro-computed tomography technology.

From Bruker BioSpin - NMR, EPR and Imaging 6 Feb 2019

Researchers discover first sour taste receptor used by flies to choose between foods

Taste is so familiar a sensation that you might think scientists had long ago sorted out how the sense works. Yet such research is far from settled.

6 Feb 2019

Chloroplast retrograde signaling attenuates elongation response to shade in plants

Plants need sunlight to feed and grow. Without light, the photosynthesis, the reaction by which the plant chloroplasts convert atmospheric CO2 and water into sugars and oxygen, cannot take place.

6 Feb 2019

Kansas geologist reveals startling global spread of antibiotic-resistant microbes

A University of Kansas geologist's work in the remote High Arctic of Norway has exposed the startling global spread of antibiotic-resistant microbes -- including multidrug-resistant "superbugs" -- that could have dire implications for human health worldwide.

6 Feb 2019

Life Science News

Cloning-free Nested CRISPR uses long DNA fragments for efficient gene editing

New research on viral biology could lead to efficient vaccines against leishmaniasis

Mutations in folliculin gene affect embryo implantation

Insufficient sleep mirrored by DNA from blood leukocytes

LABVOLUTION: A digitized lab environment to be showcased at smartLAB 2019

Detecting and mapping of chemicals inside a biological cell

Scientists untangle how microbes manufacture key antibiotic compound

New discovery can explain resistance of cancer types to fatty acid metabolism inhibition

New 'WormJam model' could provide valuable insights into human aging

Researchers understand cues controlling collective cell migration during development

Rare stem cell may be the root of all metastatic cancers

Improving sustainability of industrial laundry

Making the Most of Microdialysis for Neurotransmitter Analysis

Bruker launches new SKYSCAN 1273 benchtop 3D X-ray microscope

Researchers discover first sour taste receptor used by flies to choose between foods

Chloroplast retrograde signaling attenuates elongation response to shade in plants

Kansas geologist reveals startling global spread of antibiotic-resistant microbes

Study: BldC protein in Streptomyces acts as ‘brake’ to control timing of sporulation

HIV-1 protein plays broader role in suppressing immune response than thought

Researchers describe first case of patient affected by dysfunctions in SLC28 gene family

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

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