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Powerful two-photon microscopy for imaging fast biological processes

Two-photon microscopy (TPM) has revolutionized the field of biology by enabling researchers to observe complex biological processes in living tissues at high resolution.

4 May 2023

Revving up COVID mRNA vaccines: Algorithm generates 128-fold increase in antibodies

Research paper proposes a new method for predicting highly expressed genes based on codon usage bias and minimum free energy of mRNA secondary structures. The method involves constructing a stochastic grammar that generates sequences with high CAI and low MFE, and testing it on two mRNA vaccines.

3 May 2023

Organoid models provide new scientific insights into a rare childhood liver cancer

Scientists of the Princess Máxima Center for pediatric oncology and Hubrecht Institute in the Netherlands have revealed new scientific insights into the features of fibrolamellar carcinoma (FLC), a rare type of childhood liver cancer

3 May 2023

Researchers measure the effect of all possible variants of GCK gene

Researchers at the Department of Biology, University of Copenhagen, have now contributed to solving this problem for a specific gene called GCK. The study has just been published in Genome Biology.

3 May 2023

Diet has a much stronger impact on intestinal microbiota than defensins

Researchers at Umeå University, Sweden, have found that among the many factors that shape the intestinal microbiota composition, diet has a much stronger impact than defensins, which are intestinal defence molecules produced by the body.

3 May 2023

Finnish mitochondrial disease of newborns shows cancer-like changes in proliferating cells

A study found that a mitochondrial disease of newborns shows cancer-like changes in proliferating cells, causing tissues to age prematurely.

3 May 2023

Using PandaOmics to identify dual-purpose therapeutic targets to treat aging and glioblastoma

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 8, entitled, "Identification of dual-purpose therapeutic targets implicated in aging and glioblastoma multiforme using PandaOmics - an AI-enabled biological target discovery platform."

3 May 2023

New framework offers roadmap for developing sustainable dietary guidelines

Research paper presents a framework for developing sustainable food-based dietary guidelines that consider both nutritional requirements and environmental sustainability. The framework consists of five steps that can be adapted to any country.

2 May 2023

Researchers develop a deep learning model to classify cancer cells by type

Cancer cells that initiate metastasis, or the spread of the disease from its primary location, are different from cancer cells that stay in the original tumor. Distinguishing metastasis-initiating cell types can determine the severity of cancer and help medical practitioners decide on a course of treatment.

2 May 2023

African psychedelic plant medicine inspires new drug candidates for treating addiction and depression

Scientists have developed two new drug candidates for potentially treating addiction and depression, modeled on the pharmacology of a traditional African psychedelic plant medicine called ibogaine.

2 May 2023

Genome-based surveillance offers new hope in the fight against healthcare-associated infections

Researchers discuss major healthcare-associated pathogens, as well as current and future public health priorities related to these microorganisms.

2 May 2023

Novel chronic murine wound mouse model to study cellular senescence

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 8, entitled, "A chronic wound model to investigate skin cellular senescence."

2 May 2023

New insight into how the occludin protein mediates cell-to-cell transmission of SARS-CoV-2 virus

While the coronavirus continues to infect people around the world, researchers at the University of Missouri have identified a specific protein inside the human body that plays a critical role in how the virus spreads from cell to cell after infection -; a discovery that will help better understand the COVID-19 disease and could lead to the development of new antiviral drugs in the future.

2 May 2023

Paving the Way for New Drugs through Particle Perfection

Do particles hold the power to pave the way for new drugs? In this interview, we speak to Ben Knappett, head of science and applications at Particle Works to find out more!

From Society for Laboratory Automation and Screening (SLAS) 2 May 2023

Virologist investigates Huanan seafood market's SARS-CoV-2 origins: Unexpected genetic connections revealed

Researcher analyzes the genetic material from environmental samples collected from the Huanan Seafood Market after it was closed on January 1, 2020, to investigate the role of the market in the early SARS-CoV-2 outbreak.

1 May 2023

Structure of protein methyltransferase from the monkeypox virus deciphered

Scientists from the Institute of Organic Chemistry and Biochemistry in Prague have deciphered the structure of the protein methyltransferase from the monkeypox virus

30 Apr 2023

CRISPR-Cas9 system can help reduce adenovirus replication in human cells

The replication of potentially harmful adenoviruses can be significantly reduced in human cells in cell culture by using the so-called CRISPR-Cas9 system ("gene scissors")

29 Apr 2023

A dimensional reduction strategy for enhanced cryopreservation of red blood cells

Small amounts of nanometer-thin metal-organic layers efficiently protect red blood cells during freezing and thawing, as a team of researchers writing in the journal Angewandte Chemie has discovered. The nanolayers, made from metal-organic frameworks based on the metal hafnium, prevent ice crystal formation at very low concentrations. This effective novel cryoprotection mode could be used to develop new and more efficient cryoprotectants for the biosciences.

29 Apr 2023

Imbalanced electrical charges in biomolecular condensates spark redox reactions

The human body relies heavily on electrical charges. Lightning-like pulses of energy fly through the brain and nerves and most biological processes depend on electrical ions traveling across the membranes of each cell in our body.

28 Apr 2023

New approach for efficient engineering of cell and gene therapies

A new approach to the genetic engineering of cells promises significant improvements in speed, efficiency, and reduction in cellular toxicity compared to current methods.

28 Apr 2023

Life Science News

Powerful two-photon microscopy for imaging fast biological processes

Revving up COVID mRNA vaccines: Algorithm generates 128-fold increase in antibodies

Organoid models provide new scientific insights into a rare childhood liver cancer

Researchers measure the effect of all possible variants of GCK gene

Diet has a much stronger impact on intestinal microbiota than defensins

Finnish mitochondrial disease of newborns shows cancer-like changes in proliferating cells

Using PandaOmics to identify dual-purpose therapeutic targets to treat aging and glioblastoma

New framework offers roadmap for developing sustainable dietary guidelines

Researchers develop a deep learning model to classify cancer cells by type

African psychedelic plant medicine inspires new drug candidates for treating addiction and depression

Genome-based surveillance offers new hope in the fight against healthcare-associated infections

Novel chronic murine wound mouse model to study cellular senescence

New insight into how the occludin protein mediates cell-to-cell transmission of SARS-CoV-2 virus

Paving the Way for New Drugs through Particle Perfection

Virologist investigates Huanan seafood market's SARS-CoV-2 origins: Unexpected genetic connections revealed

Structure of protein methyltransferase from the monkeypox virus deciphered

CRISPR-Cas9 system can help reduce adenovirus replication in human cells

A dimensional reduction strategy for enhanced cryopreservation of red blood cells

Imbalanced electrical charges in biomolecular condensates spark redox reactions

New approach for efficient engineering of cell and gene therapies

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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