Life Science White Papers

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Life Science White Papers are in-depth articles aimed to educate and inform site visitors interested in life science research. Some of these papers are derived from sources where we have existing commercial relationships. Such articles are clearly labelled as sponsored content and are only accepted when the content is deemed to add value to the core editorial ethos of News Medical.

Orthogonal Analysis of Protein Aggregation Using Zetasizer Nano ZSP

Over the last two decades, arginine has been widely used as a biopharmaceutical excipient and in protein refolding experiments. The additive is an effective aggregation suppressor, but has been shown to have little effect on the conformational stability of proteins [1].

From Malvern Panalytical 21 Feb 2017

Using Quantum Cascade Laser (QCL) Mid-Infrared Spectroscopic Imaging to Study Tissue Pathology

Mid-infrared spectroscopic imaging is a powerful label-free, non-destructive, quantitative technique.

From Daylight Solutions Inc 17 Feb 2017

Emerging Biomedical Applications of Miniature Mass Spectrometry

The meticulous, careful study of minute compounds in both simple and complex mixtures has traditionally relied on conventional mass spectrometry (MS); however, MS technology can be bulky and present a substantial learning curve for new operators. Miniature mass spectrometers, however, have provided an alternative, especially for biomedical applications.

From Pittcon 10 Feb 2017

Using Mass Spectrometry to Analyze the Aging Population

The complex physiological process of aging represents many problems among rapidly aging populations. One well recognized consequence of aging is degradation of immune function, which is referred to as immunosenescence.

From Pittcon 8 Feb 2017

Studying Alzheimer’s at Single Cell Resolution

Cells vary considerably within cell populations, including within a particular type of tissue or cell. No two cells have the same response to their surroundings, since each cell’s behavior is dictated by the particular genes it expresses and at what level. This unique gene expression is what controls how the cell performs in the body.

From Pittcon 2 Feb 2017

Tools and Technologies for a Genomics Revolution

When scientists announced the completion of the Human Genome Project in 2003, it was hailed as a major scientific achievement. For the first time, we had a complete sequence for the human genome – every one of the more than three billion nucleotide bases.

From Pittcon 27 Jan 2017

Combined Imaging and Theranostic Nanoparticles for Neurological Diseases

Neurological diseases are some of the most challenging areas for drug discovery and development. There is significant unmet need in the marketplace, with an associated high degree of disability, lost productivity, and loss of quality of life.

From Pittcon 26 Jan 2017

Investigating a Neuroprotective Pentapeptide in a Murine Model of Intracerebral Hemorrhage

Intracerebral hemorrhage (ICH) refers to bleeding around or within the brain when a blood vessel in the brain ruptures. Blood leaks into the brain causing tissue injury, which leads to stroke symptoms such as weakness, blindness, numbness in one side of the body and speech loss.

From Bruker BioSpin - NMR, EPR and Imaging 20 Jan 2017

Cannabis Testing in the Legalization Era

Attitudes towards cannabis have shifted dramatically over the last two decades, and this has been reflected in recent changes to the law in many countries around the world. Just this November, an additional four US states voted to make recreational cannabis use legal, bringing the total to eight, (plus Washington DC). And over half of US states have legalized medicinal cannabis use.

From Pittcon 18 Jan 2017

Advantages of Next Generation Optima AUC over Proven ProteomeLab

Analytical ultracentrifugation has been a powerful analytical technique in the analysis of macromolecules in solution.

From Beckman Coulter Life Sciences - Centrifugation 13 Jan 2017

Technology Brings a New Age in Food Safety and Analysis

Protecting consumers has long been a priority for the food industry, but modern times have changed the specific challenges producers and regulators face when it comes to food safety. Increasing globalization presents new opportunities for food fraud with the potential for billion-dollar payoffs.

From Pittcon 9 Jan 2017

Nanotechnology Advances for Cancer Diagnostics and Nanotherapy

The delivery of drugs and diagnostic markers to cancer tissues has been a major challenge in the development of cancer therapies. Typical delivery methods distribute products throughout the body, affecting healthy and cancerous cells, thereby toxic effects to healthy cells limit the scope and effectiveness of the anticancer therapy.

From Pittcon 6 Jan 2017

Light Scattering Reveals Novel DNA Applications

Deoxyribonucleic acid (DNA) has a unique structure and stability, making it an amazingly versatile molecule. This molecule plays a critical role in the biological world as it encodes and passes on all inheritable genetic information to subsequent generations.

From Waters | Wyatt Technology 4 Jan 2017

The Seven Pitfalls of Whole Slide Scanning

Pantanowitz also cautions that digital workflows must be executed properly, and this starts with the successful digitization of glass slides by means of whole slide scanning.

From Huron Digital Pathology 4 Jan 2017

Characterizing Hydrogels for Use in Drug Delivery Systems

Drug delivery systems are technologies used to ensure the safe and effective transport of a drug around the body and its release at the desired site of action. They incorporate a range of approaches and methodologies designed to modify the drug distribution and availability in order to optimize a drug's efficacy and safety profile.

From Vitl Life Science Solutions 3 Jan 2017

Using NTA to Study Aggregation Behavior of Liposome-Protein Complexes

Aggregation of both synthetic and biological materials is a great concern, posing problems at different stages of the discovery and formulation processes. The capability to identify and characterize aggregates is of broad utility, and the experiments discussed in this article demonstrate the ability of the nanoparticle tracking analysis (NTA) technique, that is one of a kind, to comprehend the dynamics of aggregation in a biological system through high resolution particle-by-particle analysis.

From Malvern Panalytical 25 Nov 2016