Life Science White Papers

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Life Science White Papers are in-depth articles aimed to educate and inform site visitors interested in life science research. Some of these papers are derived from sources where we have existing commercial relationships. Such articles are clearly labelled as sponsored content and are only accepted when the content is deemed to add value to the core editorial ethos of News Medical.

Using Scanning Electron Microscopy in Microbiological Research

Microbial researchers at University Medical Center in Utrecht used scanning electron microscopy to examine an acute bone infection called osteomyelitis induced by Staphylococcus aureus.

From Thermo Fisher Scientific Phenom-World BV 7 Sep 2017

Benefits and Uses of IC-ICP/MS Method

Determination of elemental composition, chemical binding, and oxidation states is important for evaluating toxicity.

From Metrohm USA Inc. 5 Sep 2017

Combining Electron Paramagnetic Resonance and Atomic Force Microscopy to Elucidate Oxidative Stress in Eye Disorders

Oxidative damage is thought to underlie many age-related disorders of the eye, and can be caused by oxidative molecules as well as photooxidation from UV light. The risk of AMD increases with exposure to light, highlighting the detrimental potential of oxidation to the aging eye.

From Bruker BioSpin - NMR, EPR and Imaging 5 Sep 2017

Using TD-NMR Analysis for Fast and Reliable Quality Control for Toothpaste Production

Many ingredients are added to mouthwash and toothpaste to improve both health benefits and quality. Fluorine is one such ingredient that is added to these items to strengthen tooth enamel and thus prevent cavities. This chemical element is typically added in the amounts of 1000 to 1500 ppm.

From Bruker BioSpin - NMR, EPR and Imaging 31 Aug 2017

Analysis of Gadolinium-Based MRI Contrast Agents Using IC-ICP/MS Technique

Gadolinium contrast agents, which are mainly administered via intravenous injection, exhibit excellent in vitro and in vivo stability.

From Metrohm USA Inc. 31 Aug 2017

Electron Paramagnetic Resonance Aids Cancer Drug Development

Chromosome instability is a key hallmark of cancers, increasing mutation rates and helping tumor cells evade destruction by the immune system as well as treatment by medical interventions. Hypoxia contributes to this instability, causing replication stress and a subsequent loss of the cellular machinery required to deal with DNA damage.

From Bruker BioSpin - NMR, EPR and Imaging 30 Aug 2017

GoTaq® MDx Hot Start Polymerase: A General Purpose Reagent for Molecular Diagnostic Assays

Many PCR-based molecular diagnostic tests utilize a hot-start thermostable DNA polymerase.

From Promega Corporation 21 Aug 2017

Adopting a Best-in-Class Strategy for Digital Pathology

Anyone who is tasked with implementing a digital pathology workflow faces a dilemma - do you buy from a single vendor or take a best-in-class approach?

From Huron Digital Pathology 16 Aug 2017

Solid Fat Content Determination by Time Domain (TD) NMR Analysis

Determining solid fat content (SFC) is important in the processing and development of food products. It is essential to characterize and control raw materials like fat compositions or blends in accordance with their melting profiles.

From Bruker BioSpin - NMR, EPR and Imaging 11 Aug 2017

Using EPA 300 Method for Determination of Anions in Tap Water

Maximum Contamination Levels in drinking water are established by EPA through the Safe Drinking Water Act. EPA controls industry discharge MCL.

From Metrohm USA Inc. 9 Aug 2017

Trends and Developments of Ion Chromatography in Pharmaceutical Analysis

As a highly flexible technique, ion chromatography (IC) has many practical applications in the pharmaceutical field.

From Metrohm USA Inc. 9 Aug 2017

On-Field Determination of Arsenic, Mercury, and Copper in Ground Water

Mercury and arsenic are examples of heavy metals that can be found in ground water across many parts of the world.

From Metrohm USA Inc. 9 Aug 2017

Determination of Glyphosate and AMPA in Drinking Water Using Ion Chromatography with Pulsed Amperometric Detection

Glyphosate is a broad-spectrum herbicide that is widely used in agriculture across the globe.

From Metrohm USA Inc. 9 Aug 2017

Advantages of Using a Peristaltic Pump to Transfer Liquids

Ensuring proper liquid transfer with high precision and free of contamination is a key challenge in using pumps for liquid transfer.

From INTEGRA Biosciences 8 Aug 2017

High Resolution BOLD Functional MRI Provides New Insights on Rat Brain

Four-element array coils and high field small animal MR scanners can be used to obtain functional MRI, also known as fMRI, at a high spatial resolution of 75 x 75 x 1000 μm3. The activation area contains fine and detailed substructures, which can be identified at unparalleled in vivo resolution, thereby widening the scope and understanding of the origin and biophysical principles of blood-oxygenation-level dependent (BOLD) to get a better insight into structure and organization of the brain.

From Bruker BioSpin - NMR, EPR and Imaging 4 Aug 2017

A Guide to Buying CO2 Incubators

CO2 incubators are available in two basic types – direct heat CO2 incubator and water-jacketed CO2 incubator.

From NuAire 2 Aug 2017

Points to Consider When Purchasing Ultra-Low Temperature Freezers

Although ULT freezers are designed to work between -86°C and -45°C, they often work at a set temperature. These freezers can last for about 12 to 15 years.

From NuAire 2 Aug 2017

Assessing the Loading Capacity of HEPA Filters

When it comes to the life cycle cost of any Biological Safety Cabinet (BSC), the life of a HEPA filter is crucial.

From NuAire 2 Aug 2017

Genetically Engineering Rat Gliomas to Enable Clinically Relevant Imaging of Human Glioblastoma

Glioblastoma (GBM) is a highly malignant and aggressive primary cancer of the central nervous system. In GBM, the brain tumor or glioma arises from normal brain cells (astrocytes) and then grows very quickly, invading and residing in healthy brain tissue.

From Bruker BioSpin - NMR, EPR and Imaging 1 Aug 2017

Advantages and Applications of Bruker’s MRI CryoProbe Series

The MRI CryoProbe series from Bruker has superior resolution and provides the ultimate image with unmatched performance. MRI CryoProbes are equipped with very low temperatures, closed-cycle cooled RF-coils and preamplifiers, delivering an increased signal-to-noise ratio (SNR) by a factor of 2.5 in routine in vivo MRI applications at 9.4 T when compared to standard room temperature 1H RF-coils.

From Bruker BioSpin - NMR, EPR and Imaging 28 Jul 2017