Life Science White Papers

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Life Science White Papers are in-depth articles aimed to educate and inform site visitors interested in life science research. Some of these papers are derived from sources where we have existing commercial relationships. Such articles are clearly labelled as sponsored content and are only accepted when the content is deemed to add value to the core editorial ethos of News Medical.

Technology Brings a New Age in Food Safety and Analysis

Protecting consumers has long been a priority for the food industry, but modern times have changed the specific challenges producers and regulators face when it comes to food safety. Increasing globalization presents new opportunities for food fraud with the potential for billion-dollar payoffs.

From Pittcon 9 Jan 2017

Nanotechnology Advances for Cancer Diagnostics and Nanotherapy

The delivery of drugs and diagnostic markers to cancer tissues has been a major challenge in the development of cancer therapies. Typical delivery methods distribute products throughout the body, affecting healthy and cancerous cells, thereby toxic effects to healthy cells limit the scope and effectiveness of the anticancer therapy.

From Pittcon 6 Jan 2017

Light Scattering Reveals Novel DNA Applications

Deoxyribonucleic acid (DNA) has a unique structure and stability, making it an amazingly versatile molecule. This molecule plays a critical role in the biological world as it encodes and passes on all inheritable genetic information to subsequent generations.

From Waters | Wyatt Technology 4 Jan 2017

The Seven Pitfalls of Whole Slide Scanning

Pantanowitz also cautions that digital workflows must be executed properly, and this starts with the successful digitization of glass slides by means of whole slide scanning.

From Huron Digital Pathology 4 Jan 2017

Characterizing Hydrogels for Use in Drug Delivery Systems

Drug delivery systems are technologies used to ensure the safe and effective transport of a drug around the body and its release at the desired site of action. They incorporate a range of approaches and methodologies designed to modify the drug distribution and availability in order to optimize a drug's efficacy and safety profile.

From Vitl Life Science Solutions 3 Jan 2017

Using NTA to Study Aggregation Behavior of Liposome-Protein Complexes

Aggregation of both synthetic and biological materials is a great concern, posing problems at different stages of the discovery and formulation processes. The capability to identify and characterize aggregates is of broad utility, and the experiments discussed in this article demonstrate the ability of the nanoparticle tracking analysis (NTA) technique, that is one of a kind, to comprehend the dynamics of aggregation in a biological system through high resolution particle-by-particle analysis.

From Malvern Panalytical 25 Nov 2016

Using Nanoparticle Tracking Analysis for the Characterization of Gold-Labeled Adeno-Associated Virus

This article shows how a combination of nanoparticle tracking analysis (NTA) technique and a gold labeling method can be used to rapidly measure the concentration and size of Adeno-Associated Virus (AAV).

From Malvern Panalytical 25 Nov 2016

Using a Spero® Microscope for Large-Area Infrared Chemical Imaging of Colorectal Tissue

Mid‐infrared chemical imaging is a quantitative, non‐destructive microscopy method that can be used to visualize intrinsic biochemical markers in cells.

From Daylight Solutions Inc 23 Nov 2016

Towards automated nanoparticle synthesis in medicine

The use of nanoparticles in diagnostic and therapeutic applications has expanded in recent years, thanks largely to technological advancement and the growth of research devoted to the topic.

From Vitl Life Science Solutions 14 Nov 2016

How Mass Spec and PET/CT Unlocked a New Target for Gastric Cancer Treatments

Gastric cancer is a “silent killer”. Having few early symptoms, it is typically not diagnosed until it has reached an advanced stage.Like colon and ovarian cancer, which are also challenging to diagnose at early stages...

From Bruker BioSpin - NMR, EPR and Imaging 7 Nov 2016

A Comprehensive Guide to Protein Stability Assay Platforms

Most biotherapeutic molecules include either proteins or protein derivatives, with monoclonal antibodies (mAbs) representing the largest group of biopharmaceuticals on the market.

From Malvern Panalytical 27 Oct 2016

Using Isothermal Titration Calorimetry for Biophysical Characterization of Chromatin-Binding Proteins

Epigenetics refers to the study of heritable changes that occur in gene expression. Such changes are induced by non-genetic mechanisms, without causing any change in the DNA sequence or gene structure.

From Malvern Panalytical 27 Oct 2016

Using SBFSEM to Generate 3D Models of Skin Cells

The 3View® system is an advanced three-dimensional electron microscopy (3DEM) system that has been designed to conduct serial SBFSEM.

From Gatan, Inc. 25 Oct 2016

Analysis of Biological Materials Using Electron Energy Loss Spectroscopy

Electron energy loss spectroscopy (EELS) is used to analyze the energy distribution of the electrons that are passing through a thin sample.

From Gatan, Inc. 25 Oct 2016

LSPR Technology: The Four Most Frequently Asked Questions

Surface plasmon resonance (SPR) is a popular label-free technology that helps scientists study the binding interactions between two biomolecules in a quantitative manner.

From Nicoya Lifesciences 4 Oct 2016

Validation of NeuroTrack Assay for Medium-Throughput Testing in 96-Well Format

Understanding neurite dynamics is essential to study neuronal differentiation, embryonic development, neuronal injury and regeneration, and neuropathological disorders.

From Sartorius 3 Oct 2016

Using IncuCyte for Automatic Quantification of Live Cell Analysis

Cell migration is a basic constituent of various pathological and biological processes, such as tissue re-organization, embryonic development, angiogenesis, tumor metastasis, immune cell trafficking, and chronic inflammation.

From Sartorius 3 Oct 2016

Using Continuous Live-Cell Analysis to Meet New Requirements of Cellular Research

Continuous live-cell monitoring techniques have witnessed a significant development in recent years, transforming the way cells are used in the laboratory.

From Sartorius 3 Oct 2016

Simplifying iPSC Work Flow with IncuCyte Live Content Imaging System

Induced pluripotent stem cells (iPSCs) are characterized by the ability to self-renew and retain their pluripotency just like embryonic stem cells. As a result, they have the ability to be distinguished into any cell type of the body, making them ideal candidates for a variety of applications, including regenerative medicine, drug screening, and toxicology.

From Sartorius 3 Oct 2016

Quantitative Measurement of Cancer Cell Proliferation Using CellPlayer™ Kinetic Proliferation Assay

Cell proliferation assays are essential in developmental biology, drug safety research, and cancer therapeutic. More than 10.000 manuscripts in PubMed talk about the sustained signaling pathways that cause the progression of tumors.

From Sartorius 3 Oct 2016