Life Science White Papers

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Life Science White Papers are in-depth articles aimed to educate and inform site visitors interested in life science research. Some of these papers are derived from sources where we have existing commercial relationships. Such articles are clearly labelled as sponsored content and are only accepted when the content is deemed to add value to the core editorial ethos of News Medical.

A Comprehensive Guide to Protein Stability Assay Platforms

Most biotherapeutic molecules include either proteins or protein derivatives, with monoclonal antibodies (mAbs) representing the largest group of biopharmaceuticals on the market.

From Malvern Panalytical 27 Oct 2016

Using Isothermal Titration Calorimetry for Biophysical Characterization of Chromatin-Binding Proteins

Epigenetics refers to the study of heritable changes that occur in gene expression. Such changes are induced by non-genetic mechanisms, without causing any change in the DNA sequence or gene structure.

From Malvern Panalytical 27 Oct 2016

Using SBFSEM to Generate 3D Models of Skin Cells

The 3View® system is an advanced three-dimensional electron microscopy (3DEM) system that has been designed to conduct serial SBFSEM.

From Gatan, Inc. 25 Oct 2016

Analysis of Biological Materials Using Electron Energy Loss Spectroscopy

Electron energy loss spectroscopy (EELS) is used to analyze the energy distribution of the electrons that are passing through a thin sample.

From Gatan, Inc. 25 Oct 2016

LSPR Technology: The Four Most Frequently Asked Questions

Surface plasmon resonance (SPR) is a popular label-free technology that helps scientists study the binding interactions between two biomolecules in a quantitative manner.

From Nicoya Lifesciences 4 Oct 2016

Validation of NeuroTrack Assay for Medium-Throughput Testing in 96-Well Format

Understanding neurite dynamics is essential to study neuronal differentiation, embryonic development, neuronal injury and regeneration, and neuropathological disorders.

From Sartorius 3 Oct 2016

Using IncuCyte for Automatic Quantification of Live Cell Analysis

Cell migration is a basic constituent of various pathological and biological processes, such as tissue re-organization, embryonic development, angiogenesis, tumor metastasis, immune cell trafficking, and chronic inflammation.

From Sartorius 3 Oct 2016

Using Continuous Live-Cell Analysis to Meet New Requirements of Cellular Research

Continuous live-cell monitoring techniques have witnessed a significant development in recent years, transforming the way cells are used in the laboratory.

From Sartorius 3 Oct 2016

Simplifying iPSC Work Flow with IncuCyte Live Content Imaging System

Induced pluripotent stem cells (iPSCs) are characterized by the ability to self-renew and retain their pluripotency just like embryonic stem cells. As a result, they have the ability to be distinguished into any cell type of the body, making them ideal candidates for a variety of applications, including regenerative medicine, drug screening, and toxicology.

From Sartorius 3 Oct 2016

Quantitative Measurement of Cancer Cell Proliferation Using CellPlayer™ Kinetic Proliferation Assay

Cell proliferation assays are essential in developmental biology, drug safety research, and cancer therapeutic. More than 10.000 manuscripts in PubMed talk about the sustained signaling pathways that cause the progression of tumors.

From Sartorius 3 Oct 2016

Exosome-Depleted FBS by Ultracentrifugation

Exosomes, which are derived from the late endosome, are microvesicles that are usually described as being less than 120nm in diameter.

From Beckman Coulter Life Sciences - Centrifugation 1 Oct 2016

Overview of Continuous Flow Centrifugation

In conventional centrifugation rotors, material processing involves a number of steps, which need to be repeated until the whole sample has been processed.

From Beckman Coulter Life Sciences - Centrifugation 26 Sep 2016

Comparison of Rotor Efficiency Using k-Factor

Rotor speed can be misleading, because other factors such as temperature or geometry of the tube contribute to the performance of the rotor.

From Beckman Coulter Life Sciences - Centrifugation 26 Sep 2016

Clarification of Lipemic Serum and Removal of Fatty Particles Using Beckman Coulter Airfuge Ultracentrifuge

Blood samples of lipemia caused by chylomicrons can be cleared using the Lipemic Serum Clarification System from Beckman Coulter.

From Beckman Coulter Life Sciences - Centrifugation 26 Sep 2016

High-Speed Confocal Imaging

Confocal microscopy, or more accurately confocal laser scanning microscopy (CLSM), is a derivation of optical microscopy that allows both the optical resolution and contrast of micrographic images to be increased.

From Bruker Nano Surfaces and Metrology 23 Sep 2016

Applying Microcalorimetry for Drug Discovery Process in Modern Pharmaceutical Industry

Drug discovery process is integral to today’s pharmaceutical sector, and thus a better understanding of the interactions between a drug and a target protein forms an essential part of this process.

From Malvern Panalytical 22 Sep 2016

Using Zetasizer Nano ZSP for Protein Storage and Stability Analysis

Thanks to their elasticity and mechanical strength, the fibers have been effectively used for the rejuvenation of peripheral nerves in rats [1]. It was only recently that the manufacture of these proteins became feasible on an industrial level.

From Malvern Panalytical 22 Sep 2016

NMR Spectroscopy in Food Safety Maintenance

Food safety regulations are followed to the letter by food manufacturers, yet there are still instances in which suspicious food products—whether they’re contaminated or shipped to a continent illegally—slip through the system and end up in the public food supply.

From Bruker BioSpin - NMR, EPR and Imaging 16 Sep 2016

Micro-CT in Preclinical Imaging: Bone Regeneration in Three Dimensions

Guided bone regeneration (GBR) is a procedure that has been used in dental surgery for over 20 years for the treatment of bone loss. It involves placing bone graft material within an absorbable or non-resorbable membrane that is impermeable to epithelial cells and fibroblasts.

From Bruker BioSpin - NMR, EPR and Imaging 14 Sep 2016

Tackling antibiotic resistance through streamlined antimicrobial stewardship

Since the discovery of penicillin in 1928, antibiotics have revolutionized the treatment of infections. In the 20th century, previously common and deadly diseases, such as tuberculosis, suddenly became curable and, since then, antibiotics have become a mainstay of modern healthcare.

From Vitl Life Science Solutions 13 Sep 2016