Life Science White Papers

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Life Science White Papers are in-depth articles aimed to educate and inform site visitors interested in life science research. Some of these papers are derived from sources where we have existing commercial relationships. Such articles are clearly labelled as sponsored content and are only accepted when the content is deemed to add value to the core editorial ethos of News Medical.

Neural Markers Guide

Unique sets of cytoskeletal proteins, transcription factors, receptors, and enzymes are expressed by glia and neurons. Abcam’s user-friendly guides help in selecting the best neural subtype markers.

From Abcam 24 Jan 2018

Conformation-Specific Alpha-Synuclein Antibody for Parkinson’s Disease

In the brains of patients suffering from Parkinson's disease, misfolding and aggregation of native alpha-synuclein occurs, resulting in the formation of filamentous Lewy bodies. Aggregated alpha-synuclein can be detected by anti-alpha synuclein filament antibody (ab209530), which is a conformation-specific antibody.

From Abcam 24 Jan 2018

New Analytical Tools Extend the Boundaries of Omics Research

'Omics' research is based on non-targeted investigations that provide a holistic view of the molecules present in a cell, tissue or organism and how they change in response to environmental stimuli. The different branches of 'omics' research each focuses on a specific of cell components.

From Pittcon 22 Jan 2018

FXR Bile Acid Receptor Attenuates Cell Autophagy in Chronic Pancreatitis Patients

This study describes how TissueGnostics' Strataquest and TissueFAXS i Fluo was used to investigate the relationship between bile acid, downregulation of autophagy, and activation of the BA receptor FXR.

From TissueGnostics 18 Jan 2018

Antioxidant Properties of Coffee

Antioxidant activity in coffee beans was measured using a Bruker X-band ESR spectrometer (EMX-Plus) equipped with 100 kHz field modulation.

From Bruker BioSpin - NMR, EPR and Imaging 18 Jan 2018

Detection of Histone Proteins Using Western Blot Protocol

This article describes the detection of histone proteins using western blot protocol, which is often used at Abcam for identifying histone proteins obtained from purified calf thymus.

From Abcam 11 Jan 2018

Equipping Lab Instruments with Modern Technology to Benefit Biosafety Level 4 Labs

Biosafety is a vital aspect of laboratory management that refers to the application of safety measures in the handling of microorganisms and biological agents. The implementation of effective biosafety reduces the risk of exposure to infection, both within the laboratory environment and the world outside it.

From Vitl Life Science Solutions 10 Jan 2018

Using Bruker's minispec System for R&D and QC in the Chocolate Field

The Fat and Chocolate industries have been using the Bruker minispec for many years to make an accurate and reliable determination of fat melting profiles based on the Solid Fat Content (SFC) Determination — an indispensable process to ensure the required fat properties.

From Bruker BioSpin - NMR, EPR and Imaging 8 Jan 2018

Role of Tumor-Associated B Cells in Tumor Heterogeneity and Therapy Resistance

Melanoma is a destructive form of skin cancer and treating advanced-stage melanomas is difficult due to the fact that tumors develop resistance to most of the therapies at this stage, including drugs targeting oncogenic BRAFV600E. Moreover, strong responses to immune checkpoint therapies are observed in only one-third of melanoma patients.

From TissueGnostics 4 Jan 2018

Efficient Measurement of Coal Calorific Value

Group A is a privately listed and large, combined heat and power company.

From IKA 18 Dec 2017

Laboratory Reactor Helps Surface Technologies to Develop Textiles

Beyond Surface Technologies AG is a fast growing company based in Switzerland, developing sustainable processes for textile surfaces.

From IKA 18 Dec 2017

IKA® Reactors Save Time and Provide Greater Flexibility

ITC is a diversified company with a strong foothold in the markets of fast moving consumer goods (FMCG).

From IKA 18 Dec 2017

Forensic Identification Made Safer and More Efficient

In 1247, Song Ci, a Chinese medicolegist, wrote the first monograph for modern forensics called Collected Cases of Injustice Rectified.

From IKA 18 Dec 2017

Homogenizers Help to Enhance Drug Discovery Portfolio

Aurigene is a specialized drug discovery biotech company focusing on inflammatory and oncology diseases.

From IKA 18 Dec 2017

Conformation-Specific Aβ Antibodies - Future of Alzheimer’s Research

The complex pathology of Alzheimer’s disease may be known from the structural variation of beta amyloid (Aβ), which also emphasizes the need for conformation-specific antibodies.

From Abcam 15 Dec 2017

Tools for Detecting Neuroinflammation in Neurodegenerative Diseases

This article shows how the root cause of neurodegeneration is identified with a variety of neuroinflammation research tools to detect proinflammatory mediators, aggregated proteins and glia in Parkinson's and Alzheimer's diseases.

From Abcam 15 Dec 2017

Active Alpha-Synuclein Proteins for In Vitro and In Vivo Experiments

Active alpha-synuclein protein monomers and aggregates allow Lewy body pathology to be easily induced in neurons. They are suitable for both in vivo and in vitro experiments.

From Abcam 15 Dec 2017

Ionotropic Glutamate Receptors

In the mammalian CNS, the principle excitatory neurotransmitter is L-Glutamate, which acts through G-protein coupled (metabotropic) receptors and ligand gated ion channels (ionotropic receptors). These receptors play a key role in excitatory synaptic plasticity and synaptic transmission, which are responsible for memory and learning.

From Abcam 15 Dec 2017

minispec TD-NMR Analyzer for Determining Oil and Moisture in Seeds and Nuts

The minispec benchtop Time Domain NMR (TD-NMR) analyzer provides fast, simultaneous analysis of moisture and oil, with easy calibration.

From Bruker BioSpin - NMR, EPR and Imaging 11 Dec 2017

Determination of Hydrogen Content in Hydrocarbons Using minispec NMR Method

Hydrogenation is a process used for refining vegetable oils and hydrocarbons. Hydrogen consumption presents a significant cost issue in a refinery, whereas percentage hydrogen content serves as a key indicator of refining progress.

From Bruker BioSpin - NMR, EPR and Imaging 27 Nov 2017