Life Science White Papers

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Life Science White Papers are in-depth articles aimed to educate and inform site visitors interested in life science research. Some of these papers are derived from sources where we have existing commercial relationships. Such articles are clearly labelled as sponsored content and are only accepted when the content is deemed to add value to the core editorial ethos of News Medical.

Opening Upstream Bottlenecks in Bioprocessing Bottlenecks with Analytical Power Tools

The amazing speed with which therapeutic antibodies have come to the fore in the treatment of autoimmune disease, inflammatory conditions, and oncology, has pushed forward the race to develop novel monoclonal antibodies (mAbs).

From Sartorius 19 Jun 2018

Review: Antibody Protein Sequence Analysis Using Mass Spectrometry

During the process of research and development of antibody drug molecules, an essential step is determining the sequence of the antibody. Mass spectrometry technologies have advanced so far as to make them the first choice in sequence analysis.

From Rapid Novor Inc 18 Jun 2018

Antibody Sequencing

Antibody protein sequencing is simply defining the sequence of amino acids of an unknown antibody. The use of mass spectrometry in de novo sequencing of antibody protein has made it possible to perform this without having the cell lines available or knowing the DNA sequence beforehand.

From Rapid Novor Inc 18 Jun 2018

Measuring Double-Stranded DNA with Fluorescent Dyes: Qubit on BMG Labtech Instruments

Measuring double-stranded DNA with fluorescent dyes, is described in this article as part of applications like next generation sequencing (NGS).

From BMG LABTECH GmbH 14 Jun 2018

Testing Living Cells to Measure Cell Compression

Living cells frequently show altered mechanical properties following infection and disease. It is possible to detect whether and how any given cell is affected using quantitative tests of the mechanical stiffness of the cell membrane on a nanoscale.

From Bruker Nano Surfaces and Metrology 14 Jun 2018

Inhibition of Mitochondrial Permeability Transition Pore Evaluated by Calcium Retention Capacity Assay

A rise in inner mitochondrial membrane permeability, through consistent mitochondrial permeability transition pore opening results in mitochondrial dysfunction

From BMG LABTECH GmbH 14 Jun 2018

Combating the Opioid Epidemic with FT-Raman Spectroscopy

Fentanyl manufactured by illicit means is driving an overdose epidemic, according to data released by the Centers for Disease Control and Prevention (CDC).

From Thermo Fisher Scientific - Vibrational Spectroscopy 12 Jun 2018

Chemical Imaging for Pharmaceutical Process Analytical Technology

Mid-infrared (mid-IR) spectroscopy is an established imaging method for characterizing a broad range of materials.

From Daylight Solutions Inc 8 Jun 2018

Electrosurgical Systems Improved Through the Use of Reliable Electrical Connectors

This article looks at how electrosurgical systems have been improved through the use of reliable electrical connectors.

From Stäubli 17 May 2018

Characterising Protein - DNA Complexes

Proteins and nucleic acids often bind in stoichiometric ratios above 1:1, resulting in phenomena such as cooperativity or allosteric hindrance.

From Waters | Wyatt Technology 17 May 2018

Analysis of Expired VOCs

The Breath Analysis of Expired VOCs during Exercise markers in human breath for the determination of physiological events such as lactate threshold and oxidative stress remains a challenge for conventional ‘off-line’ gas analysis equipment, such as GCMS.

From Hiden Analytical 16 May 2018

Studying the Dynamics of Entangled Fluid Polymers

Very long linear macromolecules can occur as fluid polymers at temperatures above their point of crystallization.

From Bruker BioSpin - NMR, EPR and Imaging 8 May 2018

Biosafety Cabinets: Meeting the Industry Standards

Biosafety cabinets, create a clean and/or ventilated workspace for drug preparation, diagnosis, research, and development.

From NuAire 18 Apr 2018

Tumor Microenvironment and the Immune System Pathway

Malignant cells alone do not provide all the answers to tumor cell growth. The tumor microenvironment also plays a role.

From Abcam 18 Apr 2018

An Overview of Hedgehog Signaling Pathway

The hedgehog signaling protein (Hh) protein family act as morphogens during development in vertebrate and invertebrate species.

From Abcam 18 Apr 2018

Exploring the Structure of Elastomeric Ionomers

Elastomers, such as a rubber band, are polymers with elastic properties that enable them to be significantly deformed with minimal force. When the stress is released, the original shape is restored.

From Bruker BioSpin - NMR, EPR and Imaging 17 Apr 2018

Studying Foodborne Pathogens using Electron Microscopy

The structure of foodbourne pathogens can be studied using electron microscopy, allowing structural human-bacteria relationships to be determined.

From Thermo Fisher Scientific Phenom-World BV 4 Apr 2018

How is SEM Being Used for Pharmaceutical Research?

SEM has a wide range of applications in pharmaceutical research and is frequently used to increase our understanding of drug-cell interactions.

From Thermo Fisher Scientific Phenom-World BV 4 Apr 2018

Using Ion Chromatography and Subsequent UV/VIS Detection to Determine Nitrite and Nitrate in Tobacco

Since most nitrosamines are carcinogenic, it is essential to determine nitrite and nitrate content in tobacco.

From Metrohm USA Inc. 4 Apr 2018

Studying Blood Disorders with SEM and CLEM

SEM and CLEM can be used to study blood disorders, allowing the relationships between disease and blood cell morphology to be determined.

From Thermo Fisher Scientific Phenom-World BV 4 Apr 2018

Life Science White Papers

Opening Upstream Bottlenecks in Bioprocessing Bottlenecks with Analytical Power Tools

Review: Antibody Protein Sequence Analysis Using Mass Spectrometry

Antibody Sequencing

Measuring Double-Stranded DNA with Fluorescent Dyes: Qubit on BMG Labtech Instruments

Testing Living Cells to Measure Cell Compression

Inhibition of Mitochondrial Permeability Transition Pore Evaluated by Calcium Retention Capacity Assay

Combating the Opioid Epidemic with FT-Raman Spectroscopy

Chemical Imaging for Pharmaceutical Process Analytical Technology

Electrosurgical Systems Improved Through the Use of Reliable Electrical Connectors

Characterising Protein - DNA Complexes

Analysis of Expired VOCs

Studying the Dynamics of Entangled Fluid Polymers

Biosafety Cabinets: Meeting the Industry Standards

Tumor Microenvironment and the Immune System Pathway

An Overview of Hedgehog Signaling Pathway

Exploring the Structure of Elastomeric Ionomers

Studying Foodborne Pathogens using Electron Microscopy

How is SEM Being Used for Pharmaceutical Research?

Using Ion Chromatography and Subsequent UV/VIS Detection to Determine Nitrite and Nitrate in Tobacco

Studying Blood Disorders with SEM and CLEM

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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