Life Science White Papers

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Life Science White Papers are in-depth articles aimed to educate and inform site visitors interested in life science research. Some of these papers are derived from sources where we have existing commercial relationships. Such articles are clearly labelled as sponsored content and are only accepted when the content is deemed to add value to the core editorial ethos of News Medical.

qPCR: Guidelines for Validating a Multiplex Assay

A guide to take you through the process of validating a qPCR multiplex assay step-by-step to provide optimal results.

From Promega Corporation 6 Feb 2018

Spectrometry Utility in Biomedical Applications

At Pittcon 2018, Bruker, Gerstel, Horiba, Thermo Fisher Scientific, Lumex, and Waters, among others, will be showcasing their latest bioanalytical technologies.

From Pittcon 6 Feb 2018

Stain Free Imaging of Chemical Distribution in Biological Systems

Raman spectroscopy is an information-rich, label-free, non-invasive imaging technique perfect for life sciences research.

From Renishaw plc - Spectroscopy 5 Feb 2018

Using Structural Analysis to Improve Anti-TNF Treatments

The lowering of TNFα levels using these anti-TNFα agents significantly decreases chronic pathologic inflammatory responses in inflammatory diseases.

From Bruker BioSpin - NMR, EPR and Imaging 1 Feb 2018

Using Magnetic Compounds to Reduce Toxicity of Heavy Metal Cancer Treatments

Using a Bruker EMX-8/2.7 ESR spectrometer, Iron-salen, a heavy metal cancer treatment, was evaluated.

From Bruker BioSpin - NMR, EPR and Imaging 30 Jan 2018

Analysis and Automation in Early Pharmaceutical Development

Automation plays a major role in pharmaceutical research, mostly through high-throughput screening. Pittcon 2018 will discuss analytical technologies available for the pharmaceutical industry.

From Pittcon 30 Jan 2018

Investigating Cardiovascular Risk in Patients with Type 1 Diabetes

Diabetes is a disease in which the body is unable to control the level of sugar in the blood due to insufficient amounts of the hormone insulin or an increased resistance of cells to insulin. The resultant high blood sugar levels can lead to a range of life-threatening conditions, such as cardiovascular disease.

From Bruker BioSpin - NMR, EPR and Imaging 25 Jan 2018

Neural Markers Guide

Unique sets of cytoskeletal proteins, transcription factors, receptors, and enzymes are expressed by glia and neurons. Abcam’s user-friendly guides help in selecting the best neural subtype markers.

From Abcam 24 Jan 2018

Conformation-Specific Alpha-Synuclein Antibody for Parkinson’s Disease

In the brains of patients suffering from Parkinson's disease, misfolding and aggregation of native alpha-synuclein occurs, resulting in the formation of filamentous Lewy bodies. Aggregated alpha-synuclein can be detected by anti-alpha synuclein filament antibody (ab209530), which is a conformation-specific antibody.

From Abcam 24 Jan 2018

Role of Apolipoprotein C3 in Lipid Metabolism

apoC3 possesses some very important properties and is needed for optimal health. Reducing apoC3 to moderate levels may be beneficial for the treatment of certain types of hypertriglyceridemia, but some apoC3 expression is essential for normal lipid metabolism.

From Bruker BioSpin - NMR, EPR and Imaging 23 Jan 2018

New Analytical Tools Extend the Boundaries of Omics Research

'Omics' research is based on non-targeted investigations that provide a holistic view of the molecules present in a cell, tissue or organism and how they change in response to environmental stimuli. The different branches of 'omics' research each focuses on a specific of cell components.

From Pittcon 22 Jan 2018

FXR Bile Acid Receptor Attenuates Cell Autophagy in Chronic Pancreatitis Patients

This study describes how TissueGnostics' Strataquest and TissueFAXS i Fluo was used to investigate the relationship between bile acid, downregulation of autophagy, and activation of the BA receptor FXR.

From TissueGnostics 18 Jan 2018

Antioxidant Properties of Coffee

Antioxidant activity in coffee beans was measured using a Bruker X-band ESR spectrometer (EMX-Plus) equipped with 100 kHz field modulation.

From Bruker BioSpin - NMR, EPR and Imaging 18 Jan 2018

Using minispec Contrast Agent Analyzer for Studying the Effect of MRI Contrast Agents

The minispec Contrast Agent Analyzer is typically used to characterize and confirm the relaxation properties of pharmaceuticals called “contrast agents” for Magnetic Resonance Imaging (MRI). The system has been specifically designed to analyze the effect of pharmaceuticals (“MRI contrast agents”) on the NMR relaxation of fat or water protons.

From Bruker BioSpin - NMR, EPR and Imaging 15 Jan 2018

Detection of Histone Proteins Using Western Blot Protocol

This article describes the detection of histone proteins using western blot protocol, which is often used at Abcam for identifying histone proteins obtained from purified calf thymus.

From Abcam 11 Jan 2018

Equipping Lab Instruments with Modern Technology to Benefit Biosafety Level 4 Labs

Biosafety is a vital aspect of laboratory management that refers to the application of safety measures in the handling of microorganisms and biological agents. The implementation of effective biosafety reduces the risk of exposure to infection, both within the laboratory environment and the world outside it.

From Vitl Life Science Solutions 10 Jan 2018

Using Bruker's minispec System for R&D and QC in the Chocolate Field

The Fat and Chocolate industries have been using the Bruker minispec for many years to make an accurate and reliable determination of fat melting profiles based on the Solid Fat Content (SFC) Determination — an indispensable process to ensure the required fat properties.

From Bruker BioSpin - NMR, EPR and Imaging 8 Jan 2018

Role of Tumor-Associated B Cells in Tumor Heterogeneity and Therapy Resistance

Melanoma is a destructive form of skin cancer and treating advanced-stage melanomas is difficult due to the fact that tumors develop resistance to most of the therapies at this stage, including drugs targeting oncogenic BRAFV600E. Moreover, strong responses to immune checkpoint therapies are observed in only one-third of melanoma patients.

From TissueGnostics 4 Jan 2018

mq-ProFiler: Portable TD-NMR Analyzer for Quality Control and Research

The mq -ProFiler is a compact and portable TD-NMR analyzer that does not have any sample size restriction. It is specifically designed for industrial process/research and quality control.

From Bruker BioSpin - NMR, EPR and Imaging 18 Dec 2017