Life Science White Papers

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Life Science White Papers are in-depth articles aimed to educate and inform site visitors interested in life science research. Some of these papers are derived from sources where we have existing commercial relationships. Such articles are clearly labelled as sponsored content and are only accepted when the content is deemed to add value to the core editorial ethos of News Medical.

Antigen Characteristics

This article explains what antigen characteristics are and the best method to choose an antigen against which to raise an antibody.

From Abcam 27 Jun 2018

Combining Indentation Mapping and Raman Spectroscopy to Determine Mechanical Properties of the Tooth

A tooth is made up of enamel and dentin. The enamel is the harder outside of the tooth while the softer inside substance is the dentin.

From Bruker Nano Surfaces and Metrology 27 Jun 2018

Using Imaging Techniques to Assess the Effects of a Stroke

Cerebral ischaemia is a type of stroke causing high rates of disability and mortality. It occurs when blood vessels serving the brain become blocked or burst.

From Bruker BioSpin - NMR, EPR and Imaging 26 Jun 2018

Characterizing the Mechanical Properties of Aortic Valve Tissue

Irreparable failure of the aortic valve occurs in some patients. This requires a type of cardiac surgery called aortic valve replacement in which a healthy functioning valve is used to replace the damaged valve.

From Bruker Nano Surfaces and Metrology 20 Jun 2018

A Novel Way to Expedite Antibody Discovery with the Sartorius Mouse IgG Type and Titer Assay Kit

Monoclonal antibodies (mAbs) have become the most growth-accelerated segment of the biopharmaceutical industry, with advanced molecular engineering and antibody humanization making it possible to create therapeutic antibodies for a host of medical conditions such as cancer, autoimmune disease, cardiovascular disorders and infectious disease.

From Sartorius 19 Jun 2018

Encapsulation of Lycopene

Oxidative stress is known to be a major cause of premature aging and disease1. It is caused by the accumulation of free radicals that oxidize blood vessel walls, protein molecules, DNA, carbohydrates, and membrane lipids, changing the way cells function.

From Bruker BioSpin - NMR, EPR and Imaging 19 Jun 2018

Using Luminescence to Detect Chemotherapy Response in Patients with Colorectal Cancer

Post-operative adjuvant chemotherapy with 5-fluorouracil (5FU)-based regimens have been shown to improve patient outcome after resection of high-risk stage II and stage III colorectal tumors.

From Vitl Life Science Solutions 19 Jun 2018

Using Multiplexed Screening for Advanced Therapeutic Antibody Discovery

The use of antibodies to treat a growing array of diseases such as neoplastic tumors, cardiovascular disease, autoimmune conditions and infectious disorders are exploding in growth because of the associated success of therapy.

From Sartorius 19 Jun 2018

Opening Upstream Bottlenecks in Bioprocessing Bottlenecks with Analytical Power Tools

The amazing speed with which therapeutic antibodies have come to the fore in the treatment of autoimmune disease, inflammatory conditions, and oncology, has pushed forward the race to develop novel monoclonal antibodies (mAbs).

From Sartorius 19 Jun 2018

Review: Antibody Protein Sequence Analysis Using Mass Spectrometry

During the process of research and development of antibody drug molecules, an essential step is determining the sequence of the antibody. Mass spectrometry technologies have advanced so far as to make them the first choice in sequence analysis.

From Rapid Novor Inc 18 Jun 2018

Antibody Sequencing

Antibody protein sequencing is simply defining the sequence of amino acids of an unknown antibody. The use of mass spectrometry in de novo sequencing of antibody protein has made it possible to perform this without having the cell lines available or knowing the DNA sequence beforehand.

From Rapid Novor Inc 18 Jun 2018

Measuring Double-Stranded DNA with Fluorescent Dyes: Qubit on BMG Labtech Instruments

Measuring double-stranded DNA with fluorescent dyes, is described in this article as part of applications like next generation sequencing (NGS).

From BMG LABTECH GmbH 14 Jun 2018

Testing Living Cells to Measure Cell Compression

Living cells frequently show altered mechanical properties following infection and disease. It is possible to detect whether and how any given cell is affected using quantitative tests of the mechanical stiffness of the cell membrane on a nanoscale.

From Bruker Nano Surfaces and Metrology 14 Jun 2018

Inhibition of Mitochondrial Permeability Transition Pore Evaluated by Calcium Retention Capacity Assay

A rise in inner mitochondrial membrane permeability, through consistent mitochondrial permeability transition pore opening results in mitochondrial dysfunction

From BMG LABTECH GmbH 14 Jun 2018

Ensuring the Quality of Manufactured Heparin

Heparin is a naturally occurring anticoagulant released from mast cells. It binds reversibly with anti-thrombin, which leads to increased inactivation of coagulation enzymes, whereby preventing blood clot formation. It is a mixture of sulphated glycosaminoglycan polymers.

From Bruker BioSpin - NMR, EPR and Imaging 12 Jun 2018

Determining the Secondary Structures of Proteins

Fourier-transform infrared spectroscopy, also known as FTIR spectroscopy, has made its mark as a very versatile technique of analysis.

From Thermo Fisher Scientific – Materials & Structural Analysis 12 Jun 2018

Combating the Opioid Epidemic with FT-Raman Spectroscopy

Fentanyl manufactured by illicit means is driving an overdose epidemic, according to data released by the Centers for Disease Control and Prevention (CDC).

From Thermo Fisher Scientific – Materials & Structural Analysis 12 Jun 2018

Chemical Imaging for Pharmaceutical Process Analytical Technology

Mid-infrared (mid-IR) spectroscopy is an established imaging method for characterizing a broad range of materials.

From Daylight Solutions Inc 8 Jun 2018

Metabolomics in the Study of Soil Toxicity

Earthworms make up 60% of soil biomass and play a critical role in the turnover of soil organic matter and nutrients in both natural and agricultural settings. Earthworms live surrounded by soil and ingest soil, complete with any contaminants it may contain.

From Bruker BioSpin - NMR, EPR and Imaging 5 Jun 2018