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Gene variant in Andean populations could help predict blood cancer treatment outcomes

Two researchers from Huntsman Cancer Institute at the University of Utah (the U) have discovered a gene variant found in high-altitude Andean populations that they believe could be a new biomarker for predicting the severity of diseases and treatment responses for certain types of blood cancer.

14 Dec 2024

Researchers discover key genetic mechanism behind craniofacial development

An international team of researchers has identified a key genetic mechanism that regulates the formation and migration of cranial neural crest cells, which are essential for developing facial structures.

14 Dec 2024

Scientists reveal the spread of highly drug-resistant cholera strain

Scientists from the National Reference Center for Vibrios and Cholera at the Institut Pasteur, in collaboration with the Centre hospitalier de Mayotte, have revealed the spread of a highly drug-resistant cholera strain.

14 Dec 2024

Plant-based beverages may not be as nutritious as cow's milk

Over the last decade, the global market for plant-based beverages has seen remarkable growth, with oat, almond, soy and rice drinks emerging as popular alternatives to cow's milk in coffee and oatmeal during this time.

14 Dec 2024

ZEST trial fails to meet enrollment goals for ctDNA testing in breast cancer

The ZEST clinical trial, designed to evaluate niraparib (Zejula) for the prevention of breast cancer recurrence in patients with circulating tumor DNA (ctDNA), failed to accrue enough patients positive for ctDNA, according to results presented at the San Antonio Breast Cancer Symposium (SABCS), held December 10-13, 2024.

14 Dec 2024

Study unveils key mechanism behind prostate cancer's uncontrolled growth

Prostate cancer hijacks the normal prostate's growth regulation program to release the brakes and grow freely, according to Weill Cornell Medicine researchers.

14 Dec 2024

Machine learning model predicts CDK4/6 inhibitor effectiveness in metastatic breast cancer

A machine learning (ML) model incorporating both clinical and genomic factors outperformed models based solely on either clinical or genomic data in predicting which patients with hormone receptor (HR)-positive, HER2-negative metastatic breast cancer would have better outcomes from adding CDK4/6 inhibitors to endocrine therapy as first-line treatment, according to results presented at the San Antonio Breast Cancer Symposium (SABCS), held December 10-13, 2024.

14 Dec 2024

Targeted gene therapy shuts down cancer cells' energy centers

Researchers are shining a light on cancer cells' energy centers – literally – to damage these power sources and trigger widespread cancer cell death.

14 Dec 2024

Adjuvant anthracycline- plus taxane-based chemotherapy regimen improves survival in high-risk breast cancer patients

Patients with early-stage, node-negative, hormone receptor (HR)-positive, HER2- negative breast cancer who have a high risk of recurrence based on the OncotypeDX genomic test had better outcomes when treated with adjuvant anthracycline- plus taxane-based chemotherapy regimens compared with those receiving adjuvant taxane-based chemotherapy regimens alone, according to results presented at the San Antonio Breast Cancer Symposium (SABCS), held December 10-13, 2024.

14 Dec 2024

TTUHSC researcher to uncover mechanisms that regulate gene expression in Alzheimer's disease

More than six million Americans are affected by Alzheimer's disease, a form of dementia marked by accumulation of amyloid-β within the brain. Amyloid-β is a relatively small protein that forms toxic plaques in the brain contributing to the harmful effects of Alzheimer's disease.

14 Dec 2024

Exploring the cytotoxic potential of neocryptolepine derivatives against cancer

Announcing a new publication for Acta Materia Medica journal. Cancer has been a severe public health and social problem, a leading disease that has diminished the quality of life, and a barrier to improving life expectancy.

13 Dec 2024

Zeqi exhibits multifunctional therapeutic potential in modern medicine

Announcing a new publication for Acta Materia Medica journal. Zeqi (Euphorbia helioscopia L.), is a widely distributed plant of the Euphorbiaceae family.

13 Dec 2024

New technique offers safer option for head and neck reconstruction

Sometimes, moving just a few inches can go a long way. Osaka Metropolitan University researchers have developed a promising technique for head and neck reconstruction that shifts the placement of transferred tissue with blood vessels attached, offering a safer, faster option for patients with complex tissue defects, especially those at high risk.

13 Dec 2024