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New method uses sugar molecules to identify pancreatic cancer subtypes

Van Andel Institute scientists and collaborators have developed a new method for identifying and classifying pancreatic cancer cell subtypes based on sugars found on the outside of cancer cells.

9 Apr 2025

Eating ultra-processed foods may rewire your brain’s hunger and reward circuits

High intake of ultra-processed foods is linked to adverse metabolic health and microstructural brain changes in regions that control appetite and reward. These effects occur both through obesity-related pathways and independently via inflammation and dyslipidemia.

9 Apr 2025

Tim-3 identified as promising therapeutic target for Alzheimer's disease

Tim-3 is an immune checkpoint molecule involved in immunity and inflammation recently linked to late-onset Alzheimer's disease (AD), but its role in the brain was unknown until now.

9 Apr 2025

New STITCHR tool offers a promising step forward for gene therapy

Investigators from Mass General Brigham and Beth Israel Deaconess Medical Center have developed STITCHR, a new gene editing tool that can insert therapeutic genes into specific locations without causing unwanted mutations.

9 Apr 2025

ETH Zurich researchers identify redundancies between the genes involved in DNA repair

Researchers aThe DNA of human cells consists of a sequence of about 3.1 billion building blocks. Cells go to great lengths to maintain the integrity of this vast store of information.t ETH Zurich have unraveled the complex network that cells use to repair their genetic material.

9 Apr 2025

Menstrual cycle may drive inflammation in women with sickle cell disease

A marker linked to inflammation, C-reactive protein, may increase significantly during the follicular phase of the menstrual cycle in female patients with sickle cell disease (SCD), according to emerging research published today in Blood Vessels, Thrombosis & Hemostasis.

9 Apr 2025

Mirvie reveals new advances in the biological understanding of hypertensive disorders of pregnancy

Today, Mirvie announced results of a breakthrough study published in Nature Communications, revealing new advances in the biological understanding of hypertensive disorders of pregnancy (HDP), including preeclampsia - a leading cause of maternal morbidity and mortality as well as preterm birth.

9 Apr 2025

Political affiliation reflected in the brain even during mundane activities

People's political affiliation can be shown in their brain activity when they carry out mundane chores such as buying food, a new study shows.

9 Apr 2025

Doctors urged to rethink prescribing parkrun as a health intervention

General practitioners are now "prescribing" parkrun for their patients as part of a social prescribing initiative to promote preventative care.

9 Apr 2025

Gum disease linked to worsening liver health

There is growing recognition in medicine that what happens in one part of the body can ripple through others.

9 Apr 2025

Handheld electro shockers may disrupt pacemakers and heart devices

Research has found that handheld electro-shockers commonly used for self defense can potentially interact with cardiac implantable electronic devices (CIEDs) such as pacemakers, putting individuals at risk.

9 Apr 2025

Increased allergy symptoms tied to changing climate patterns

A review published in The Laryngoscope indicates that climate change's effects on pollen seasons and concentrations are contributing to increasing rates of allergic rhinitis, or hay fever.

9 Apr 2025

Fish swim bladder hydrogel shows promise in heart repair

Hydrogels, which are soft materials formed by crosslinking polymers, could have a variety of medical applications.

9 Apr 2025

Qualified midwifery care reduces medical interventions during childbirth

A study carried out by researchers from the University of Granada (UGR), in collaboration with the Andalusian Association of Midwives, has determined that the healthcare provided by these qualified professionals has a positive impact on health and on the functioning of healthcare systems internationally.

9 Apr 2025

Laser-based infrared molecular fingerprinting detects common cancers

Cancer diagnoses traditionally require invasive or labor-intensive procedures such as tissue biopsies.

9 Apr 2025

Dynamic BH3 profiling offers personalized lung cancer therapies

Eighty-five percent of diagnosed cases of lung cancer are non-small cell lung cancer (NSCLC). In this group, 5% of patients show molecular alterations in the ALK gene involved in cell multiplication.

9 Apr 2025

Study reveals sex differences in bone regeneration

Bone regeneration continues to be a critical challenge in tissue engineering, with unpredictable outcomes often hindering clinical application. Current strategies overlook key factors such as donor differences and biological sex, both of which play a significant role in fracture healing.

9 Apr 2025

Oral health emerges as key factor in women's pain disorders

New research from the University of Sydney has revealed poor oral health is significantly associated with higher instances of migraines, abdominal and body pain in women.

9 Apr 2025

Cell-by-cell analysis reveals brain changes in Tourette syndrome

In the first comprehensive, cell-by-cell analysis of brain tissue from individuals with Tourette syndrome, researchers have pinpointed exactly which cells are perturbed and how they malfunction, revealing how different types of brain cells are affected by the condition.

9 Apr 2025

Neural organoids offer insight into mechanisms of dementia

Researchers at The Ohio State University Wexner Medical Center and College of Medicine have discovered a new way that neurons act in neurodegeneration by using human neural organoids – also known as "mini-brain" models – from patients with frontotemporal lobar degeneration (FTLD).

9 Apr 2025