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NIDDK Catalyst Award funds research on mammary gland's role in metabolic diseases

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Catalyst Award program has awarded a $4 million, five-year grant to Prashant Rajbhandari, PhD, Assistant Professor of Medicine (Endocrinology, Diabetes and Bone Disease) at the Mount Sinai Diabetes, Obesity, and Metabolism Institute, to investigate a new frontier in understanding metabolic diseases like obesity and type 2 diabetes.

27 Aug 2024

Innovative AI tool targets missing data to enhance sepsis risk predictions

A proposed artificial intelligence tool to support clinician decision-making about hospital patients at risk for sepsis has an unusual feature: accounting for its lack of certainty and suggesting what demographic data, vital signs and lab test results it needs to improve its predictive performance.

27 Aug 2024

Urban noise pollution found to have significant negative impact on heart health

Research from two studies in different European cities1,2 highlights that urban noise pollution has a significant negative impact on heart health, according to data presented at ESC Congress 2024.

27 Aug 2024

New insights into γδ T cells could improve treatment for colorectal cancer

The most common form of colorectal cancer, microsatellite-stable colorectal cancer (MSS CRC), can currently only be treated to a limited extent with modern immunotherapies.

27 Aug 2024

Study illuminates CDCA7's role in DNA methylation

DNA methylation, a process by which methyl groups are added to DNA molecules, is essential for the maintenance of DNA and the overall health of an organism.

27 Aug 2024

Study reveals how different types of love activate the brain

We use the word 'love' in a bewildering range of contexts - from sexual adoration to parental love or the love of nature.

27 Aug 2024

Menopause transition linked to changes in blood cholesterol and cardiovascular risk

New research presented at the ESC Congress 2024 in London, UK (30 August - 2 September) shows that women in the menopause transition period show changes in their blood cholesterol profiles which could have an adverse impact on their cardiovascular health.

27 Aug 2024

New ESC atlas data highlights disparities in cardiovascular disease mortality

Cardiovascular disease (CVD) remains the most common cause of death across Europe but while CVD mortality rates are generally decreasing, the decline is much less in middle-income than in high-income countries, according to new data from the European Society of Cardiology (ESC) Atlas of Cardiology, published in the European Heart Journal.

27 Aug 2024

Study reveals a rare genotype with significant impact on women's health

Scientists at deCODE genetics and collaborators, have identified a sequence variant in the CCDC201 gene that when inherited from both parents homozygous causes menopause on average nine years earlier.

27 Aug 2024

Virtual voice technology enhances follow-up care for TAVI patients

Clinical follow-up using virtual voice technology helped identify complications after transcatheter aortic valve implantation (TAVI) with a high degree of patient satisfaction, according to research presented at ESC Congress 2024.

27 Aug 2024

New techniques in RNA engineering promise longer-lasting therapies

New methods to shape RNA molecules into circles could lead to more effective and long-lasting therapies, shows a study by researchers at the University of California San Diego.

27 Aug 2024

Global health experts reveal widespread concerns about drinking water safety

A new study finds more than half of adults surveyed worldwide expect to be seriously harmed by their water within the next two years.

27 Aug 2024

New insights on how melanoma cells resist cancer immunotherapy

Immune checkpoint inhibitors are cancer fighting drugs that help the immune system do its job of detecting and attacking tumor cells.

27 Aug 2024

Breakthrough miniaturized brain-machine interface enables brain-to-text communication

Researchers from EPFL have developed a next-generation miniaturized brain-machine interface capable of direct brain-to-text communication on tiny silicon chips.

27 Aug 2024

Novel bottom-up approach in synthetic immunology opens a new frontier for disease treatment

Synthetic immunology, an innovative field of research which could lead to fundamentally new approaches and methods in the treatment of infectious diseases and cancer, is the topic of an article in the "Perspectives" section of the journal "Nature Nanotechnology". Herein, Heidelberg researchers Prof. Dr. Kerstin Göpfrich, Prof. Dr. Michael Platten, Prof. Dr. Friedrich Frischknecht, and Prof. Dr. Oliver T. Fackler describe a so-called bottom-up approach that uses the toolbox of nanotechnology and synthetic biology to construct systems from molecular building blocks and specifically equip them with immune functions.

27 Aug 2024

Common chemotherapy supplement weakens the pancreatic cancer's defenses in mice

The fight against cancer is an arms race, and one of the most effective weapons in clinicians' arsenals is immunotherapy. Immune checkpoint therapy has become the standard for treating several types of cancer.

27 Aug 2024

An Arm and a Leg: Don’t get ‘bullied’ into paying what you don’t owe

Caitlyn Mai thought she did everything right. She called ahead to make sure her insurer would cover her cochlear implant surgery.

27 Aug 2024

With only gloves to protect them, farmworkers say they tend sick cows amid bird flu

In early August, farmworkers gathered under a pavilion at a park here for a picnic to celebrate Farmworker Appreciation Day. One sign that this year was different from the others was the menu: Beef fajitas, tortillas, pico de gallo, chips, beans — but no chicken.

27 Aug 2024

EPAM Joins Sapio Sciences Partner Program

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From Sapio Sciences 27 Aug 2024

AI enhances understanding of radiation-induced cardiac arrhythmia risk in lung cancer patients

Researchers from Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare system, have used artificial intelligence tools to accelerate the understanding of the risk of specific cardiac arrhythmias when various parts of the heart are exposed to different thresholds of radiation as part of a treatment plan for lung cancer.

27 Aug 2024