Medical White Papers

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Medical White Papers are in-depth articles aimed to educate and inform site visitors interested in medical research. Some of these papers are derived from sources where we have existing commercial relationships. Such articles are clearly labelled as sponsored content and are only accepted when the content is deemed to add value to the core editorial ethos of News Medical.

Measuring the Molecular Weight of Molecules via Static Light Scattering

Measuring the Molecular Weight of Molecules via Static Light Scattering

Static Light Scattering is a technique for measuring the molecular weight of molecules. As the molecular weight of a macromolecule is closely linked to it's properties, SLS is an excellent technique for molecular characterization.

From Bettersize Instruments Ltd. 5 Mar 2021

Lysozyme: Investigating the Thermal Denaturation, Molecular Weight and Particle Size

Lysozyme: Investigating the Thermal Denaturation, Molecular Weight and Particle Size

Lysozyme is an antimicrobial enzyme that functions as a part of the innate immune system. Due to it's relatively simple structure, it is a popular model for biological research in particle size, molecular weight and thermal denaturation

From Bettersize Instruments Ltd. 5 Mar 2021

$What to Know Before Refractive Lens Replacement Surgery$

What to Know Before Refractive Lens Replacement Surgery

Refractive Lens Replacement Surgery is a procedure in which the lens of an eye is replaced with an implant lens. The surgery is utilized in order to correct near or far-sightedness and astigmatism. It is typically carried out for 50+ citizens.

From Dr Alex Day - Ophthalmologist 4 Mar 2021

A New ELISA for COVID-19 Seroconversion Detection: The Basics

A New ELISA for COVID-19 Seroconversion Detection: The Basics

COVID-19 has resulted in unprecedented disruption to the world. Quick, accurate, and reliable diagnosis of the SAR-CoV-2 virus is incredibly important. ELISA assays against SARS-CoV-2 could provide a powerful diagnostic tool.

From Bethyl Laboratories, Inc. 1 Mar 2021

Utilizing TIGIT in the Targeting of T and NK Cells

Utilizing TIGIT in the Targeting of T and NK Cells

T cell immunoglobulin and ITIM domain (TIGIT) is a target for potential immune checkpoint therapies. TIGIT expression can cause T cell exhaustion and NK cell immunosuppression. Thus, it is thought that targeting TIGIT could help reactivate T and NK cells while also suppressing tumor expansion.

From Bethyl Laboratories, Inc. 1 Mar 2021

An Emerging Cancer Target and Epigenetic Regulator: BRD4

An Emerging Cancer Target and Epigenetic Regulator: BRD4

Bromodomain Protein 4 (BRD4) is an epigenetic regulator and emerging cancer target. It plays role in inflammatory diseases, autoimmune disease, and cancer. It also plays roles in cell cycle control and differentiation, thus making it a therapeutic target.

From Bethyl Laboratories, Inc. 1 Mar 2021

Hypoxic Signaling: Recombinant Rabbit Monoclonal Antibodies for HIF1-alpha and HIF2-alpha

Hypoxic Signaling: Recombinant Rabbit Monoclonal Antibodies for HIF1-alpha and HIF2-alpha

HIF1-alpha and HIF2-alpha overexpression are associated with poor cancer survival rate. They are crucial to the hypoxic response and there has been a lot of research into the development of selective HIF inhibitors.

From Bethyl Laboratories, Inc. 1 Mar 2021

Tyramide Signal Amplification: How Does It Affect Multiplex Immunohistochemistry?

Tyramide Signal Amplification: How Does It Affect Multiplex Immunohistochemistry?

Tyramide signal amplification is an imaging improvement that has allowed for mmunohistochemistry to improve beyond the traditional fluorescence approaches. It has resulted in more accurate visualization.

From Bethyl Laboratories, Inc. 1 Mar 2021

Multiplex Immunohistochemistry: An Introduction

Multiplex Immunohistochemistry: An Introduction

Understanding the tumor microenvironment is a huge challenge. Immunohistochemistry is a tool to examine protein expression, activation, and distribution. It has a variety of applications across many scientific fields.

From Bethyl Laboratories, Inc. 1 Mar 2021

Albumin: A Marker of Tissue Damage and Organ Function

Albumin: A Marker of Tissue Damage and Organ Function

Albumin has several applications across a variety of molecular biology and biomedical fields. Bethyl’s Mouse Albumin ELISA kit is a versatile reagent that can be utilized as a marker for organ function and tissue damage.

From Bethyl Laboratories, Inc. 1 Mar 2021

Checkpoint Blockade Therapies: Ushering in the Second Wave

Checkpoint Blockade Therapies: Ushering in the Second Wave

Checkpoint blockade therapies are becoming more and more commonplace as they are a useful tool against tumors. They work by reactivating immune cells present in a tumor to attack and potentially destroy the cancerous cells.

From Bethyl Laboratories, Inc. 1 Mar 2021

Using Bethyl Laboratories Antibodies to Improve T-Cell Marker Research

Using Bethyl Laboratories Antibodies to Improve T-Cell Marker Research

T-Cell marker panels allow for the identification of T-cells associated with tumors. This allows researchers to identify and therefore target T-cell subpopulations that are associated with cancers.

From Bethyl Laboratories, Inc. 28 Feb 2021

Reagent Validation Via ENCODE: A Free, Publicly Funded Source

Reagent Validation Via ENCODE: A Free, Publicly Funded Source

ENCODE is a NIH funded effort to provide data on the human genome. It's antibody database allows for the cross referencing of various brands and cell lines in order to get the best reagent for your needs.

From Bethyl Laboratories, Inc. 27 Feb 2021

Mobile Air Quality Monitoring with Real-Time Mobile VOC Monitors

Mobile Air Quality Monitoring with Real-Time Mobile VOC Monitors

IONICON real-time mobile VOC monitors are frequently operated in mobile measurement labs and are utilized for mobile air quality monitoring.

From Ionicon Analytik Ges.m.b.H. 23 Feb 2021

Research and Development Progress of a SARS-CoV-2 Neutralizing Antibody

Research and Development Progress of a SARS-CoV-2 Neutralizing Antibody

It has been one year since the outbreak of COVID-19, but there is still an increasing number of confirmed cases. The epidemic situation is still challenged all over the world.

19 Jan 2021

Developing a Phase Appropriate CMC Program

Developing a Phase Appropriate CMC Program

From funding, regulatory guidance, timing and outsourcing there are a lot of factors in developing a phase appropriate CMC program.

From DSI, a PLG Company 22 Jul 2020

Development Plan for CMC Strategy

Development Plan for CMC Strategy

Chemistry, manufacturing and controls are a key quality marker of emerging biotech companies and require a clear development plan for CMC strategy.

From DSI, a PLG Company 22 Jul 2020

What You Need to Understand About CMC Regulatory Affairs

What You Need to Understand About CMC Regulatory Affairs

Providing an overview of what you need to understand about CMC regulatory affairs and information to be reviewed as part of routine drug development activities.

From DSI, a PLG Company 22 Jul 2020

CMC Discussion Topics Around Your Product Development

CMC Discussion Topics Around Your Product Development

Seeking early guidance from regulators can be invaluable and there are plenty of CNC discussion topics that should be raised during your product development.

From DSI, a PLG Company 22 Jul 2020

Regulatory Considerations Moving from Phase 2 to Phase 3

Regulatory Considerations Moving from Phase 2 to Phase 3

ROI is a crucial consideration when moving from phase 2 to phase three on the path to pharmaceutical product approval. This article describes the opportunities.

From DSI, a PLG Company 22 Jul 2020

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