Catalyst Pharmaceutical Partners first-quarter net loss decreases to $0.06 per basic and diluted share

Catalyst Pharmaceutical Partners, Inc. (Nasdaq: CPRX) today announced its financial results for the three month period ended March 31, 2010.  The Company reported a net loss of $1,045,043, or $0.06 per basic and diluted share, compared to a net loss of $3,031,201, or $0.22 per basic and diluted share, for the same period in 2009.

Research and development expenses for the first quarter of 2010 were $439,587, compared to $2,460,632 in the first quarter of 2009. The reduction is the result of decreased clinical trial activity in the first quarter of 2010 as compared to the prior year. The Company expects that research and development expenses will increase during the balance of 2010. General and administrative expenses for the first quarter of 2010 totaled $610,825, compared to $583,911 in the first quarter of 2009.

As a development stage pharmaceutical company, Catalyst has no revenues to-date.

At March 31, 2010, the Company had cash and cash equivalents of $6.8 million and no debt. The Company believes that its existing cash and cash equivalents will be sufficient to fund the Company's ongoing and previously announced CPP-109 and CPP-115 research and development activities and to continue its operations through at least the second quarter of 2011 without the need for additional funding.

First Quarter Accomplishments

• Signed a non-binding Letter of Intent with the National Institute on Drug Abuse (NIDA) to collaborate on a U.S. Phase II(b) clinical trial to evaluate CPP-109 for the treatment of cocaine addiction.
• Completed the chemical synthesis and characterization of the drug substance, CPP-115.
• Continued partnering activities by presenting at the BioNetworks East Conference.
• Presented CPP-115 data and development plans at the Epilepsy Pipeline Update Conference.

Significant Recent and Upcoming Events

• Signed the definitive Clinical Trial Agreement with NIDA to commence the Phase II(b) trial referred to above.  The Company expects to enroll 200 subjects at eight sites across the United States.  Catalyst expects to contribute approximately $2.8 million in resources toward the total estimated $10 million trial costs.
• Commenced non-clinical safety and efficacy studies for CPP-115.
• Presented data from Catalyst's recently completed Phase II(a) cocaine addiction trial at The American Society of Addiction Medicine Annual Medical-Scientific Conference in April 2010
• Scheduled to present CPP-109 data at College on Problems of Drug Dependency in June 2010.
• Expect to commence CPP-109 U.S. Phase II(b) trial in the summer of 2010, with top-line results expected in the fourth quarter of 2011.

"We are very pleased to be moving forward with NIDA on the Phase II(b) trial," said Patrick J. McEnany, Catalyst's Chief Executive Officer. "In addition, we are also in the process of conducting various non-clinical studies of CPP-115 evaluating its safety and efficacy in animal models for addiction, epilepsy and neuropathic pain.  Moving forward, we will continue to explore partnering opportunities for both CPP-109 and CPP-115, as well as to seek non-dilutive financing in various forms."