Roche launches new xCELLigence System RTCA HT Instrument

The new xCELLigence System RTCA HT Instrument from Roche Diagnostics (SIX:RO)(SIX:ROG)(OTCQX:RHHBY) rounds out the company's portfolio in real-time cell analysis with a high-throughput product. The new instrument merges the power and flexibility of xCELLigence System technology with high-throughput analyses and workflows for automated screening applications. The system allows researchers to run 1 to 4 plates independently on up to four RTCA HT stations, thus reading 4 x384 well plates in parallel. Integration with automated plate and liquid handling systems is also an option. The instrument was launched worldwide and will be available in all markets during the next months.

“The new RTCA HT Instrument has the potential to become the benchmark system in real-time label-free, automated HTS and automated long-term cytotoxicity screening”

The cell-based xCELLigence System assays perfectly integrate micro electronics and cell biology, offering a number of advantages over conventional cell analysis systems. The system is suitable for uninterrupted monitoring of real-time kinetics and processes in living cells and supplies a densely concentrated stream of information. Sensitivity and reproducibility are excellent for monitoring the overall cell population of a cell culture.

"The new RTCA HT Instrument has the potential to become the benchmark system in real-time label-free, automated HTS and automated long-term cytotoxicity screening," says Ruedi Stoffel, Life Cycle Leader for Cellular Analysis at Roche Diagnostics.

The heart of the system is a microelectronic biosensor built into each well of the E-Plate microtiter plates. A cell in contact with the sensor changes the electrical impedance between the microelectrodes. Each change in the cell's status, e.g., changes in cell adhesion, cytotoxicity, cell proliferation, cell-to-cell interactions and morphological changes lead to changes in the impedance measurements and can therefore be easily and quickly detected in real-time. In combination with the RTCA DP Instrument and CIM-Plate 16, the xCELLigence System product line also allows cancer researchers to conduct direct studies of cell migration and invasion, eliminating the need for labeling cells, a process that can induce non-physiological changes in the cells.

Source:

Roche

Citations

Please use one of the following formats to cite this article in your essay, paper or report:

  • APA

    Roche Sequencing and Life Science. (2019, June 20). Roche launches new xCELLigence System RTCA HT Instrument. News-Medical. Retrieved on July 14, 2024 from https://www.news-medical.net/news/20101214/Roche-launches-new-xCELLigence-System-RTCA-HT-Instrument.aspx.

  • MLA

    Roche Sequencing and Life Science. "Roche launches new xCELLigence System RTCA HT Instrument". News-Medical. 14 July 2024. <https://www.news-medical.net/news/20101214/Roche-launches-new-xCELLigence-System-RTCA-HT-Instrument.aspx>.

  • Chicago

    Roche Sequencing and Life Science. "Roche launches new xCELLigence System RTCA HT Instrument". News-Medical. https://www.news-medical.net/news/20101214/Roche-launches-new-xCELLigence-System-RTCA-HT-Instrument.aspx. (accessed July 14, 2024).

  • Harvard

    Roche Sequencing and Life Science. 2019. Roche launches new xCELLigence System RTCA HT Instrument. News-Medical, viewed 14 July 2024, https://www.news-medical.net/news/20101214/Roche-launches-new-xCELLigence-System-RTCA-HT-Instrument.aspx.

Comments

The opinions expressed here are the views of the writer and do not necessarily reflect the views and opinions of News Medical.
Post a new comment
Post

While we only use edited and approved content for Azthena answers, it may on occasions provide incorrect responses. Please confirm any data provided with the related suppliers or authors. We do not provide medical advice, if you search for medical information you must always consult a medical professional before acting on any information provided.

Your questions, but not your email details will be shared with OpenAI and retained for 30 days in accordance with their privacy principles.

Please do not ask questions that use sensitive or confidential information.

Read the full Terms & Conditions.

You might also like...
Roche launches new protein melting application for real-time PCR LightCycler 1536 instrument