Globavir, BioManguinhos partner to jointly evaluate PanGlob RT-PCR Dengue diagnostic assay

Globavir Biosciences, Inc. ("Globavir"), a biotechnology company developing diagnostic and therapeutic technologies to treat infectious diseases, has announced a partnership with BioManguinhos, a division of the Oswaldo Cruz Foundation (Fiocruz), for a joint evaluation of Globavir's PanGlob™ RT-PCR Dengue diagnostic assay. Under the terms of the agreement both parties will work jointly to evaluate and develop PanGlob for commercial launch in Brazil. PanGlob in comparison to any other Dengue diagnostic assays, is more sensitive in detecting the Dengue virus in patient samples. This collaboration may result in future joint ventures or technology transfers.

The PanGlob™ RT-PCR Dengue diagnostic assay is capable of identifying the presence of Dengue RNA in a sample of extracted nucleic acid, regardless of the serotype of the specific virus. In preliminary studies, PanGlob™ demonstrated a higher sensitivity and specificity for Dengue detection, and over a longer window of infection, than other currently available tests. A point-of-care version of the diagnostic test is currently under development.

Dengue virus, which is carried by the Aedes aegypti mosquito, infects at least 3 million Brazilians each year according to current estimates. Dengue virus is seasonal in Brazil, with infections rising during late summer and early autumn (February – April).

"We feel strongly that Globavir's PanGlob™ diagnostic will provide a badly needed weapon in combating Dengue infections in Brazil," said Dr. Shalabh Gupta, Globavir's President and CEO. "Accurately diagnosing clinical samples is the first step to identifying and controlling outbreaks. Through this partnership with BioManguinhos, Globavir's powerful diagnostic assay will be in position for deployment during the next Dengue season."


Globavir Biosciences, Inc.


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