New risk scoring system for acute type A aortic dissection to assess mortality

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Acute type A aortic dissection (ATAAD) is a catastrophic disease with fatal outcomes. Malperfusion syndrome (MPS) is a serious complication of ATAAD, with an incidence of 20-40%. Many studies have shown that MPS is the main risk factor for poor ATAAD prognosis. However, a risk scoring system for ATAAD based on MPS is lacking. Here, we designed a risk scoring system for ATAAD to assess mortality through quantitative assessment of relevant organ malperfusion and subsequently develop rational treatment strategies.

This was a prospective observational study. Patients' perioperative clinical data were collected to establish a database of ATAAD (N≥3000) and determine whether these patients had malperfusion complications. The Anzhen risk scoring system was established on the basis of organ malperfusion by using a random forest survival model and a logistics model. The better method was then chosen to establish a revised risk scoring system.

Source:
Journal reference:

Jia, B., et al. (2023) The Anzhen Risk Scoring System for Acute Type A Aortic Dissection: A Prospective Observational Study Protocol. Cardiovascular Innovations and Applications. doi.org/10.15212/CVIA.2023.0002.

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