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Analyte testing in pediatric and emergency room settings is limited by both false-positive and false-negative results using traditional immunoassay methods. False positives result from antibody cross-reactivity, and false negatives occur from dilute urine specimens or a limited scope of analyte targets. Direct-to-mass spectrometry (MS) protocols provide definitive identification and lower limits of detection, mitigating the risks of both false negatives and positives. While successful implementation has been demonstrated in single-hospital settings, broader adoption remains limited by substantial capital investment and the technical demands of MS-based workflows.
In this webinar, you will learn potential strategies for overcoming these barriers. By addressing logistical and economic challenges, direct-to-definitive analyte testing can become a scalable, reliable, and clinically valuable tool across diverse healthcare systems.
For Research Use Only - Not for use in Clinical Toxicology.
Join the free webinar with certification of attendance.
Attend the Webinar to Learn:
- Limitations of traditional immunoassay analyte testing
- How LC-MS/MS improves sensititivity and specificity
- Benefits of direct-to-definitive testing in pediatric and ER settings
- Strategies to enable broader adoption of MS-based workflows
This Webinar is Ideal For:
- Clinical laboratory directors and managers
- Clinical chemists and endocrinologists
- LC-MS/MS scientists and assay developers
- Hospital laboratory professionals
- Independent clinical laboratories (ICLs)
Meet the Webinar Speaker
Dennis J. Dietzen is the Megan K Dishop endowed Chair of Pathology and Laboratory Medicine at Phoenix Children’s Hospital. He was formerly a Professor of Pathology at Washington University in St. Louis and Director of Laboratory Services at St. Louis Children’s Hospital. He has been a member of ADLM/AACC and the Academy for nearly 30 years, serving as AACC President in 2018 and currently serves as Chair of the Policy and External Affairs Core Committee (PEACC). Dr. Dietzen’s research focus is mass spectrometry applications in pediatrics including rapid detection of drugs, metabolic disorders, liver failure, pre-eclampsia, and neonatal hypoglycemia. He has authored more than 100 peer-reviewed manuscripts, monographs, editorials, and book chapters.