How to easily profile protein samples

Profiling protein samples, either by size or charge, is easy with Maurice. This instrument integrates two capillary electrophoresis (CE) detection schemes, streamlining method development to a single day and enabling rapid data collection within minutes.

Difficult molecules for charge characterization are no longer a problem

For fusion proteins with complex hydrophobic antibody-drug conjugates (ADCs) or charge variants, ion exchange chromatography often struggles with poor resolution. Maurice/iCE significantly improves resolution and reproducible peak pattern within ten minutes.

How to easily profile protein samples

Image Credit: Bio-Techne

Resolve mixed proteins with Maurice’s icIEF Native Fluorescence

Analysis of therapeutic co-mixtures can be challenging whenever two proteins are present in substantially different abundance. The video below explains how Maurice's icIEF Native Fluorescence detection can be used to accurately study and quantify multiple products within one sample.

Utility of Maurice icIEF Native Fluorescence in icIEF Analysis of Protein Mixtures

Video Credit: Bio-Techne

No mess, no fuss

Maurice's intelligent, ready-to-use cartridges automate column conditioning and clean-up. The cartridge design enables the seamless switch of separation modes between CE-SDS and cIEF, without fear of cross-contamination.

The handling of toxic waste, such as ADCs, is eliminated since waste is collected in the cartridge. Usability is enhanced by an on-board sample mixer, which reduces the operator-dependent variability often seen in other systems.

How to easily profile protein samples

Image Credit: Bio-Techne

Maurice: Perfect for big pipelines and tight schedules

Heterogeneity data and pl are produced by Maurice in under 10 minutes. Size-based CE-SDS data can be prepared in less than 8 minutes. The fast separation time offers a robust, streamlined, and automated solution for method development within a day. You can also explore platform methods and utilize them for numerous molecules.

How to easily profile protein samples

Image Credit: Bio-Techne

About Bio-Techne

Bio-Techne Corporation is a leading developer and manufacturer of high-quality purified proteins - notably cytokines and growth factors, antibodies, immunoassays, as well as biologically active small molecule compounds - which are sold to biomedical researchers and clinical research laboratories; these operations constitute the core Biotech Division, headquartered in Minneapolis, Minnesota.

The Protein Platform Division manufactures innovative protein analysis tools under the ProteinSimple brand name that greatly automate western blotting and immunoassay practices. The Diagnostics Division manufactures FDA-regulated controls, calibrators, blood gas, and clinical chemistry controls for OEM customer and clinical customers. Bio-Techne products assist scientific investigations into biological processes and the nature and progress of specific diseases. They aid in drug discovery efforts and provide the means for accurate clinical tests and diagnoses.

With thousands of products in its portfolio, Bio-Techne generated approximately $563 million in net sales in fiscal 2017 and has approximately 1,800 employees worldwide.


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Last updated: Jan 8, 2024 at 12:55 PM

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