It is important in clinical trials, exploratory studies, proof-of-concept analysis, and research and development to acquire samples most suitable for desired results.
Both processing methods—formalin-fixed paraffin-embedded (FFPE) and flash-frozen—effectively preserve biospecimens. However, the choice between them depends upon the specific application.
- Can be stored at room temperature for an extended period
- Advantageous for immunohistochemical (IHC) staining
- Widespread availability
- Formalin is toxic and typically not suitable for molecular analysis
- Processing protocols lack standardization, resulting in samples being processed differently. It is crucial to have a biorepository with strict Quality Assurance and Quality Control processes in place
- Suitable for molecular analysis, including DNA/RNA quality and extraction, and gene expression and sequencing
- Maintains sample integrity and molecular viability
- Suitable for mutation analysis
- Increased shipping expenses
- Deteriorates at room temperature
- Not suitable for IHC staining
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Our Research Services team works collaboratively with clients to provide in vitro hepatic modeling solutions. And as the world’s premier supplier of ADME-Tox model systems, including hepatocytes and subcellular fractions, BioIVT enables scientists to better understand the pharmacokinetics and drug metabolism of newly discovered compounds and the effects on disease processes. By combining our technical expertise, exceptional customer service, and unparalleled access to biological specimens, BioIVT serves the research community as a trusted partner in ELEVATING SCIENCE®.
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