Antibiotic Resistance News and Research

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Mass treatment with the antibiotic azithromycin may lead to increased drug resistance

Efforts to reduce child mortality in Africa via mass treatment with the antibiotic azithromycin (AZM) may lead to increased drug resistance in bacteria that frequently cause pneumonia and meningitis, highlighting the need for careful monitoring, finds a new study led by UCL.

4 Jun 2025

Understanding antibiotic resistance mechanisms in Mycobacterium species

Announcing a new article publication for BIO Integration journal. Tuberculosis (TB) is caused by Mycobacterium tuberculosis (M.tb) complex (MTBC), which includes M.tb as one of the causative bacteria.

3 Jun 2025

Flea protein inspires breakthrough in preventing medical implant infections

A protein that gives fleas their bounce has been used to boot out bacteria cells, with lab results demonstrating the material's potential for preventing medical implant infection.

2 Jun 2025

Tuberculosis bacteria use molecular switch to pause and restart growth

The bacteria that cause tuberculosis (TB) may have an "on-off switch" that lets them pause and restart growth, according to a new study from the University of Surrey and the University of Oxford.

23 May 2025

New glycopeptide antibiotic discovered to combat resistant bacteria

An international team of researchers, led by the University of Vienna and the Helmholtz Institute for Pharmaceutical Research Saarland, has discovered saarvienin A, a new type of glycopeptide antibiotic.

14 May 2025

Researchers find 8,500 tonnes of antibiotics enter rivers every year

A global study led by McGill University estimates that 8,500 tonnes of antibiotics enter river systems annually, mostly from human use—even after wastewater treatment. The findings warn that chronic exposure poses risks to aquatic life and fuels antibiotic resistance, especially in regions with poor sanitation.

10 May 2025

Scientists build world's most accessible gut bacteria collection to unlock health and disease clues

Researchers have developed the Human Intestinal Bacteria Collection (HiBC), comprising 340 gut bacterial strains from 198 species, including 29 newly described taxa, made publicly available for functional microbiome research.

7 May 2025

Most deadly drug-resistant infections in poorer countries go untreated, study shows

A new modelling study reveals that only 7% of carbapenem-resistant Gram-negative (CRGN) bacterial infections in eight LMICs receive effective antibiotic treatment. This stark undertreatment poses a major threat in the global fight against antimicrobial resistance (AMR).

7 May 2025

New rifamycin drugs fight antibiotic-resistant lung infections more effectively

Researchers have developed next-generation rifamycin analogs that effectively kill both replicating and nonreplicating Mycobacterium abscessus while minimizing drug-drug interactions. Lead candidates UMN-120 and UMN-121 showed superior efficacy to current treatments in mouse models and retained potency against M. tuberculosis.

5 May 2025

Rising antibiotic resistance threatens UTI treatment in Malawi

A growing resistance to antibiotics is complicating the treatment of urinary tract infections (UTIs) in Malawi, with new research revealing that nearly half of women presenting with symptoms at a major referral hospital had infections resistant to multiple drugs.

3 May 2025

Mathematical models point to broader antibiotic use as a tool against cholera

Cholera kills thousands of people and infects hundreds of thousands every year-and cases have spiked in recent years, leaving governments with an urgent need to find the best ways to control outbreaks.

29 Apr 2025

Research offers new hope in the fight against antibiotic-resistant bacteria

Antibiotic resistance is a serious threat to public health. When antibiotics don't work, we risk not being able to treat many types of infections and people who would previously have been cured, can die.

23 Apr 2025

New approach to treating chronic pain without opioids

Chronic pain, a common and debilitating condition, often leads practitioners to prescribe opioids in escalating doses.

22 Apr 2025

Fecal microbiota transplantation emerges as a promising approach to H. pylori eradication

FMT is a novel therapeutic approach that involves transferring microbiota from a healthy donor to a patient's gastrointestinal tract.

10 Apr 2025

Unexpected function of gene network in gut microbes revealed

Could a gene regulatory network in gut microbes have evolved its elaborate and tightly regulated molecular machinery only to pump out antibiotics indiscriminately? Researchers from the Institute of Science and Technology Austria (ISTA) show this is an auxiliary function.

8 Apr 2025

AI model enhances detection of antibiotic resistance in deadly bacteria

Drug-resistant infections - especially from deadly bacteria like tuberculosis and staph - are a growing global health crisis.

7 Apr 2025

New guidelines aim to improve diagnosis and treatment of mycoplasma pneumoniae in children

The Chinese Medical Association has released new guidelines for diagnosing and treating Mycoplasma pneumoniae in children.

7 Apr 2025

New insights into bacterial defense mechanisms could help combat antibiotic resistance

Antibiotic resistance is a global health challenge that could overtake cancer mortality within a few decades.

4 Apr 2025

European study reveals stabilization patterns in antibiotic resistance

Antibiotic resistance tends to stabilize over time, according to a study published April 3, 2025 in the open-access journal PLOS Pathogens by Sonja Lehtinen from the University of Lausanne, Switzerland, and colleagues.

4 Apr 2025

Study: Jumbo phages utilize EPI vesicles to evade bacterial immune response

In a growing global trend, bacteria have evolved new ways to maneuver around medical treatments for a variety of infections. The rising antibiotic resistance crisis poses a significant public health threat in hospitals and other settings, with infections resulting in millions of deaths in recent years.

4 Apr 2025