Flow Cytometry News and Research

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Flow cytometry is a technique for counting and examining microscopic particles suspended in a stream of fluid. It allows simultaneous multiparametric analysis of the physical and/or chemical characteristics of single cells flowing through an optical and/or electronic detection apparatus.

Research uncovers mechanisms governing SARS-CoV-2 Omicron subvariant entry

In a recent study posted to the bioRxiv* preprint server, researchers at Ohio State University and the University of Texas Medical Branch assessed the underlying mechanisms involved in the fusogenicity and endosomal entry of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron subvariants.

20 Oct 2022

Impaired SARS-CoV-2 neutralization after booster vaccination in the elderly

A recent study investigates poorer vaccine responses observed in the elderly following receipt of a COVID-19 booster vaccination dose.

19 Oct 2022

Beckman Coulter Life Sciences launches Cytobank v10 platform

Beckman Coulter Life Sciences, a global leader in laboratory automation and innovation, introduces an automated solution for the grueling and time-consuming process of manual gating flow cytometry data, with no programming skills required.

From Beckman Coulter Life Sciences 19 Oct 2022

Study explores the effect of COVID-19 on platelet function

A new study posted in the pre-print server bioRxiv* aimed to analyze the impact of COVID-19 on platelet proteome and relate the functional responses of platelets and the formation of platelet-neutrophil aggregate in hospitalized COVID-19 patients.

17 Oct 2022

Study finds memory B cell clones harbor the capacity to adopt multiple and functionally different fates in COVID-19 patients

Researchers examined single clones of SARS-CoV-2-specific memory B cells to understand their adaptability and fate.

13 Oct 2022

What is the association between interferon genes and complement regulatory protein expressions in SARS-CoV-2 infections?

Researchers investigated the expression of complement regulatory proteins (CRPs) in coronavirus disease 2019 (COVID-19) to identify potential dysregulated CRP patterns and investigate whether they contribute to COVID-19 pathogenesis.

13 Oct 2022

Intranasal vaccine represents an effective broad-spectrum COVID-19 vaccine strategy

Researchers evaluated the efficacy of dNS1-RBD, a novel intranasal COVID-19 vaccine.

6 Oct 2022

A novel method to identify spike stabilizing mutations for COVID-19 vaccine development

Researchers discuss a robust method to identify mutations that improve the expression and stabilize the conformation of the SARS-CoV-2 spike protein.

29 Sep 2022

PerkinElmer unveils industry-first cell analysis solution to streamline cell and gene therapy research and manufacturing

PerkinElmer, Inc., (NYSE: PKI), a global leader committed to innovating for a healthier world, today launched the Cellaca® PLX Image Cytometry System, a first-of-its-kind benchtop platform that enables researchers to assess multiple Critical Quality Attributes (CQAs) of cell samples in a single automated workflow, including cell identity, quality and quantity.

From Revvity 29 Sep 2022

Study suggests B-cell responses to booster vaccines are impeded by recent SARS-CoV-2 infection

Researchers investigated whether the time of booster vaccination relative to SARS-CoV-2 infection is a crucial determinant of the elicited immune response; in particular, the antibody and B-cell responses.

29 Sep 2022

Study demonstrates how pan-sarbecovirus ORF7a protein plays a role in evading host immunity

In a new study, researchers demonstrated how sarbecovirus family down-regulates major histocompatibility complex-I (MHC-I) surface expression to evade cellular immunity.

26 Sep 2022

Omicron BA.1 breakthrough infection in vaccinated individuals recall memory B cells to confer immunity

In a new study, researchers followed up with individuals vaccinated with a COVID-19 vaccine based on the mRNA platform up to six months following Omicron BA.1 breakthrough infection to trace the evolution of their antibody immunity.

26 Sep 2022

What is the association between body fat and COVID-19?

Researchers recently assessed the association between adipose tissues and COVID-19 by evaluating autopsy cases and profiling adipose tissue responses to SARS-CoV-2 infections.

26 Sep 2022

Common germline variants of APOE contribute to differential COVID-19 outcomes

Researchers investigated the relationship between APOE4 genotype and COVID-19 outcomes using genetic models of mice.

26 Sep 2022

A fast and powerful method for the production of SARS-CoV-2 virus-like particles in insect cells

Researchers presented the direct plasmid transfection method for SARS-CoV-2 virus-like particle production in insect cells and applied the VLPs to evaluate the efficacy of monoclonal antibodies and vaccinated donor sera.

26 Sep 2022

A good night's sleep promotes immunity

In a recent study published in the Journal of Experimental Medicine, researchers in the United States used mice models to understand how sleep fragmentation affects immunological responses and the epigenetic modifications of hematopoietic stem and progenitor cells (HSPCs). They also conducted a sleep restriction trial in humans to determine HPSC programming and hematopoiesis.

25 Sep 2022

Flow Cytometry News and Research

Further Reading

Research uncovers mechanisms governing SARS-CoV-2 Omicron subvariant entry

Impaired SARS-CoV-2 neutralization after booster vaccination in the elderly

Beckman Coulter Life Sciences launches Cytobank v10 platform

Study explores the effect of COVID-19 on platelet function

Study finds memory B cell clones harbor the capacity to adopt multiple and functionally different fates in COVID-19 patients

What is the association between interferon genes and complement regulatory protein expressions in SARS-CoV-2 infections?

Intranasal vaccine represents an effective broad-spectrum COVID-19 vaccine strategy

A novel method to identify spike stabilizing mutations for COVID-19 vaccine development

PerkinElmer unveils industry-first cell analysis solution to streamline cell and gene therapy research and manufacturing

Study suggests B-cell responses to booster vaccines are impeded by recent SARS-CoV-2 infection

Study demonstrates how pan-sarbecovirus ORF7a protein plays a role in evading host immunity

Omicron BA.1 breakthrough infection in vaccinated individuals recall memory B cells to confer immunity

What is the association between body fat and COVID-19?

Common germline variants of APOE contribute to differential COVID-19 outcomes

A fast and powerful method for the production of SARS-CoV-2 virus-like particles in insect cells

A good night's sleep promotes immunity

Study explores the effect of age-associated B cells on COVID-19 vaccine-induced immunity

Vaccination drives superior functional antibody breadth compared to natural infection with SARS-CoV-2

New antiviral mechanism of action for an FDA-approved thiopurine known as 6-thioguanine

Overload of stress granules enables the growth of obesity-related pancreatic cancer

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