immunity News and Research

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Experimental two‑in‑one vaccine shows success in human LASSARAB trial

Researchers from Thomas Jefferson University and the University of Maryland School of Medicine have reported encouraging results from the first human clinical trial of LASSARAB, an experimental vaccine designed to protect against Lassa fever and rabies in a single formulation.

9 Jun 2026

Moderate alcohol consumption linked to premature death and chronic illness

Even what many Americans consider moderate drinking is linked to an increased risk of death, disability, and chronic diseases such as cancer and heart disease, according to a new study published in the Journal of Studies on Alcohol and Drugs.

9 Jun 2026

Study links menstrual cycle timing to COVID vaccine side effects

A study of 1,474 Clue app users found that women vaccinated against COVID-19 during the follicular phase had higher odds of self-reported side effects than those vaccinated during the luteal phase.

8 Jun 2026

Defective HIV copies explain persistent viral traces during treatment

Antiretroviral drugs for HIV infection have enabled most people living with the virus to live long and healthy lives.

8 Jun 2026

Research highlights ongoing TORCH infection risks despite rising vaccination rates

The TORCH complex is a group of pathogens that can cause infections with mild or silent symptoms in an expecting mother, but in a developing fetus can lead to serious complications that include stillbirth, lifelong disability, or birth defects.

8 Jun 2026

Hidden junk DNA could play decisive role in cancer

Many repetitive regions of the genome have been considered "junk DNA" because the technologies available did not allow them to be studied at sufficient resolution.

5 Jun 2026

Scientists discover new intracellular immune defense against infections

When we think of the immune system, most people imagine white blood cells putting up a fight against invading germs within our bloodstream.

4 Jun 2026

Modified injectable vaccine shows promise for complete polio eradication

In the United States, children routinely receive an injectable form of the polio vaccine. This vaccine is very effective at preventing illness, but it doesn't block transmission of the polio virus as well as the oral polio vaccine does.

3 Jun 2026

CAR-T cell therapy shows promise for treating rheumatoid arthritis

Current therapies for rheumatoid arthritis rely on sustained immunosuppression rather than restoration of immune tolerance, with off-drug remission remaining rare.

3 Jun 2026

Microenvironmental CTHRC1 protein promotes colorectal cancer tumor growth

A new research paper was published in Volume 17 of Oncotarget on May 20, 2026, titled "Microenvironmental CTHRC1 has a pro-tumorigenic role in colorectal cancer."

2 Jun 2026

New atlas provides unprecedented overview of dendritic cell diversity across cancers

Researchers from VIB, VUB, and an international network of collaborators have created the most comprehensive single-cell atlas to date of tumor-associated dendritic cells.

1 Jun 2026

Understanding mitochondrial biology in alcohol-associated liver disease and cancer

For decades, giant mitochondria-known as megamitochondria-have been recognized in liver biopsies from patients with alcohol-associated liver disease (ALD).

1 Jun 2026

Hypoxia-gated AAV enables targeted treatment for advanced NSCLC

Adeno‑associated virus (AAV) vectors offer safety and durable expression but lack tumor specificity. This hypothesis proposes an NSCLC‑directed, hypoxia‑responsive AAV platform that integrates MGS4 peptide‑guided capsid targeting with dual hypoxia‑responsive element (HRE)‑gated promoters driving Q‑CXCL9‑Fc (chemokine) and miR‑30‑based shRNA against mesothelin (MSLN).

1 Jun 2026

Immediate kangaroo mother care boosts survival for premature infants

Preterm birth and low birth weight remain major contributors to neonatal death and long-term developmental challenges.

29 May 2026

Macrophage location within tumors may influence cancer progression outcomes

Cancer tumors are surrounded by immune cells, but not all of those cells help the body fight back. Some support anti-cancer immunity, while others can unexpectedly help tumors survive.

26 May 2026

Ferroptosis exploits unique cancer metabolic vulnerabilities to bypass traditional apoptotic evasion pathways

A new wave of scientific understanding is placing ferroptosis, a distinct form of iron-dependent cell death, at the forefront of efforts to overcome drug resistance in digestive cancers. These cancers, which include gastric, colorectal, liver, pancreatic, and esophageal malignancies, remain among the most challenging to treat due to their ability to evade standard therapies.

25 May 2026

Small non-coding RNA molecule precisely controls vital gene expression and cellular balance

A rapidly advancing area of biomedical innovation is shining a spotlight on miR-128-3p, a small yet powerful molecule with the potential to reshape how diseases—especially cancer—are detected, monitored, and treated. This microRNA, part of a broader class of non-coding RNAs, plays a critical role in regulating gene activity and maintaining cellular homeostasis.

25 May 2026

Metabolic reprogramming helps tumor cells adapt and evade the human immune system

A newly published review article highlights the critical role of fatty acid metabolism in shaping the tumor microenvironment and influencing cancer progression, offering fresh perspectives for the development of more effective therapies.

25 May 2026

Sting signaling stimulates vital immune defenses to actively suppress aggressive tumor growth

A new review brings attention to the STING pathway as a critical regulator in both colitis and colon cancer, highlighting its complex and often opposing roles in inflammation and tumor development. The findings underscore how this key component of the innate immune system can act as both a driver of disease and a protective mechanism, depending on biological context.

25 May 2026

New review highlights how glutamine metabolism shapes the complex tumor microenvironment

A new review article highlights the expanding importance of glutamine metabolism in shaping the tumor microenvironment, offering fresh perspectives on how metabolic interactions influence cancer progression and therapeutic response

25 May 2026

immunity News and Research

Experimental two‑in‑one vaccine shows success in human LASSARAB trial

Moderate alcohol consumption linked to premature death and chronic illness

Study links menstrual cycle timing to COVID vaccine side effects

Defective HIV copies explain persistent viral traces during treatment

Research highlights ongoing TORCH infection risks despite rising vaccination rates

Hidden junk DNA could play decisive role in cancer

Scientists discover new intracellular immune defense against infections

Modified injectable vaccine shows promise for complete polio eradication

CAR-T cell therapy shows promise for treating rheumatoid arthritis

Microenvironmental CTHRC1 protein promotes colorectal cancer tumor growth

New atlas provides unprecedented overview of dendritic cell diversity across cancers

Understanding mitochondrial biology in alcohol-associated liver disease and cancer

Hypoxia-gated AAV enables targeted treatment for advanced NSCLC

Immediate kangaroo mother care boosts survival for premature infants

Macrophage location within tumors may influence cancer progression outcomes

Ferroptosis exploits unique cancer metabolic vulnerabilities to bypass traditional apoptotic evasion pathways

Small non-coding RNA molecule precisely controls vital gene expression and cellular balance

Metabolic reprogramming helps tumor cells adapt and evade the human immune system

Sting signaling stimulates vital immune defenses to actively suppress aggressive tumor growth

New review highlights how glutamine metabolism shapes the complex tumor microenvironment

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