Aging News and Research

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Research shows exercise can delay Alzheimer’s, but there’s a catch

Regular physical activity slows the accumulation of p-tau181, a key Alzheimer’s biomarker, but its cognitive benefits diminish when tau levels are high.

26 Feb 2025

Pilot study explores potential of senolytics in Alzheimer's prevention

A new pilot study known as STAMINA (Senolytics To Alleviate Mobility Issues and Neurological Impairments in Aging), that focused on the effects of senolytic medications, Dasatinib and Quercetin (DQ), which remove old (senescent) cells from the body, suggests that intermittent treatment may hold promise for improving cognitive function in older adults at risk of Alzheimer's disease.

26 Feb 2025

Discovery of stable genes offers insights into aging and longevity

A new research paper was published in Aging (Aging-US) on January 27, 2025, in Volume 17, Issue 1, titled "Age-invariant genes: multi-tissue identification and characterization of murine reference genes."

26 Feb 2025

NSHAP study examines cognition and aging in post-COVID era

A new supplemental issue of The Journals of Gerontology, Series B: Psychological Sciences and Social Sciences presents new measures, methods, and data collected during Round 4 (2021 to 2023) of the National Social Life, Health, and Aging Project (NSHAP) - with a focus on cognition and how researchers adapted to working with participants as a result of the COVID-19 pandemic.

26 Feb 2025

Hormones may offer new way to treat wrinkles and hair graying

Hormones may be leveraged to treat and prevent signs of aging such as wrinkles and hair graying, according to a new study published in the Endocrine Society journal Endocrine Reviews.

26 Feb 2025

Organ aging measured by blood test may help predict age-related diseases

Our organs age at different rates, and a blood test determining how much they've each aged could predict the risk of conditions like lung cancer and heart disease decades later, finds a new study led by University College London (UCL) researchers.

26 Feb 2025

Stochastic analysis sheds light on ovarian aging and menopause timing

Menopause, driven by ovarian aging and the depletion of ovarian reserve, marks the end of a woman's fertility, and while many aspects of these processes are well understood, the overall dynamics remain unclear.

25 Feb 2025

Breast cancer cases and deaths set to surge by 2050—are we prepared?

A global study finds that breast cancer cases will rise by 38% and deaths by 68% by 2050, with the highest incidence in Australia and New Zealand and worsening mortality in low-income countries.

25 Feb 2025

Insilico Medicine reaches preclinical milestone in MASH drug discovery

Insilico Medicine("Insilico"), a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, recently achieved preclinical milestone in its collaboration with Therasid Bioscience, a South Korean based biotechnology company focuses on developing innovative first-in-class drugs for treatment for metabolic dysfunction-associated steatohepatitis (MASH).

25 Feb 2025

Mass General Brigham study uncovers 16 novel Alzheimer's risk genes

Investigators from Mass General Brigham have conducted a multi-ancestry, whole genome sequencing association study of Alzheimer's disease and found evidence for 16 new susceptibility genes, expanding the study of Alzheimer's disease in underrepresented groups.

25 Feb 2025

Study finds higher odds of hypothyroidism among South Asian immigrants in Canada

A new study published this week in Archives of Gerontology and Geriatrics Plus found that 10% of South Asian immigrants aged 45 and older in Canada had hypothyroidism.

25 Feb 2025

Higher 'bad' cholesterol levels may help Sardinia’s seniors live longer, study finds

Higher LDL cholesterol levels (≥130 mg/dL) were linked to longer survival in Sardinian nonagenarians, challenging the conventional belief that lower cholesterol is always better. However, very high cholesterol levels, particularly in women, did not show additional longevity benefits.

24 Feb 2025

New AI tool measures brain aging speed and predicts cognitive health

A new artificial intelligence model measures how fast a patient's brain is aging and could be a powerful new tool for understanding, preventing and treating cognitive decline and dementia, according to USC researchers.

24 Feb 2025

Study shows how herpes viruses contribute to Alzheimer's disease in aging brains

Researchers from Cleveland Clinic's Genome Center outlined the pathway human herpes simplex virus-1 (HSV1) can use to contribute to Alzheimer's disease in aging brains.

24 Feb 2025

Study uncovers pathway behind age-related degeneration of eye glands

A team led by Mount Sinai researchers has identified stem cell populations and mechanisms underlying age-related degeneration in glands that are vital to eye function.

24 Feb 2025

New drug ataciguat shows promise for managing aortic valve stenosis

Aortic valve stenosis (AVS) is a significant health concern affecting over 1.5 million Americans and millions more globally.

24 Feb 2025

Telemedicine adoption leads to fewer low-value medical tests

Low-value care-medical tests and procedures that provide little to no benefit to patients-contributes to excess medical spending and both direct and cascading harms to patients.

24 Feb 2025

Study finds key p53 targets for future cancer treatment

A new research paper was published in Oncotarget, Volume 16, on February 18, 2025, titled "Robust p53 phenotypes and prospective downstream targets in telomerase-immortalized human cells."

24 Feb 2025

"Normal" vitamin B12 levels may not prevent brain decline

Researchers identify associations between B12 levels currently accepted as normal and markers of neurological injury or impairment.

24 Feb 2025

Aging isn’t just in your genes—your environment plays a bigger role, study shows

Study explores the relative contributions of genetics and environmental factors to aging and premature mortality. It highlights how the exposome—lifetime environmental exposures—shapes disease risks, with socioeconomic status, smoking, and lifestyle choices emerging as key aging determinants.

23 Feb 2025