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Research highlights guselkumab's impact on Crohn's endoscopic healing

In a major advance for patients with Crohn's disease, a new study led by researchers at Mount Sinai Health System found that guselkumab, a medication with a mechanism of action that is new to inflammatory bowel disease (IBD) treatment, outperformed an established standard of care in promoting intestinal healing and symptom relief.

18 Jul 2025

PAR1 protein found to boost lung fluid drainage during injury

A protein called PAR1 helps lymphatic vessels structurally transform to boost fluid drainage and support healing when the lungs are injured according to researchers from Weill Cornell Medicine.

18 Jul 2025

Uncovering a protective RNA molecule in kidney stress and disease

Cells contain helper molecules called transfer RNAs (tRNAs), which carry building blocks (amino acids) to make proteins.

17 Jul 2025

CRISPR-mediated DNA methylation editing regulates inflammation and tumor growth

Genes, fragments of DNA located on our chromosomes, control much of what happens in cells.

17 Jul 2025

New tool measures how quickly muscles age to predict sarcopenia risk

A new research paper was published in Aging (Aging-US) Volume 17, Issue 6, on June 9, 2025, titled "Developing a quantitative estimate of muscle age acceleration by a novel phenotypic clock: cross-sectional study in healthy, middle-aged and older adults."

17 Jul 2025

Study reveals how aging alters liver function and structure

The aging liver undergoes dramatic changes in its functional organization and other key attributes, which may underpin its increasing susceptibility to disease, according to a study led by investigators at Weill Cornell Medicine.

17 Jul 2025

New molecular pathway identified in alcohol-associated liver disease

Excessive alcohol consumption causes alcoholic liver disease, and about 20% of these cases progress to alcohol-associated steatohepatitis (ASH), which can lead to liver cirrhosis and liver failure. Early diagnosis and treatment are therefore extremely important.

17 Jul 2025

New genetic marker improves kidney transplant match predictions

Researchers at the University of Pittsburgh have identified a new way of predicting whether a kidney donor and recipient are a good match for transplantation.

17 Jul 2025

Targeting GLUD1 shows promise in restoring muscle function in Duchenne muscular dystrophy

New research has identified the enzyme glutamate dehydrogenase 1 (GLUD1) as a new therapeutic target for Duchenne muscular dystrophy (DMD).

17 Jul 2025

TTUHSC researcher focuses on how brain endothelial cells handle stressors of neuroinflammation

Each year in the U.S., approximately 2.5 million people suffer traumatic brain injuries (TBIs). About 50,000 of these injuries will result in death, and more than 80,000 will lead to permanent disability.

16 Jul 2025

New adhesive could offer a more comfortable alternative for medical device users

Wearable healthcare devices, such as glucose monitors and heart monitors, are popular due to their ability to gather real-time data that supports users' health and safety.

16 Jul 2025

Why buckwheat may be the best flour for gluten-free baking

Research shows buckwheat flour leads in gluten-free scone acceptability, emphasizing its role in enhancing texture and taste in gluten-free bakery products.

16 Jul 2025

New 3D bio-printed model closely mimics the complexity of natural lung tissue

UBC Okanagan researchers have developed a 3D bio-printed model that closely mimics the complexity of natural lung tissue, an innovation that could transform how scientists study lung disease and develop new treatments.

15 Jul 2025

New computational tool uncovers hidden genes behind heart and metabolic diseases

Genetic changes can signal evidence of disease, but pinpointing which genes and what's changed can be difficult.

15 Jul 2025

New cellular entry pathway improves gene therapy outcomes

Scientists from the Centenary Institute and the University of Sydney have made a landmark discovery that could lead to safer and more effective gene therapies for a range of serious genetic disorders including Duchenne muscular dystrophy, Pompe disease and hemophilia.

15 Jul 2025

Americans divided on how to manage neck and back pain, survey reveals

New survey data from the Orlando Health Spine Center reveals a significant difference among Americans on how to manage neck and back pain.

15 Jul 2025

Long sitting hours raise breast cancer odds for inactive obese women

Prolonged daily sitting is linked to a higher prevalence of breast cancer in obese women, but only among those who are physically inactive. Regular physical activity eliminates this association, highlighting the importance of movement for breast cancer prevention in high-risk groups.

15 Jul 2025

New autoimmune target identified in pediatric idiopathic nephrotic syndrome

Idiopathic nephrotic syndrome (INS) is a serious kidney disease in children with no clear cause. In a recent study, researchers have identified a novel autoantibody targeting vinculin—a protein crucial for kidney cell structure—as a significant factor in INS.

14 Jul 2025

Study reveals key role of Egr-1 in controlling autoimmune diseases

Autoimmune diseases, like multiple sclerosis result when the body's immune system starts to attack its own cells. Regulatory T cells, a subtype of T cells play a critical role in suppressing these attacks.

14 Jul 2025

Nasal antibody spray shields mice from pollen-triggered allergies and asthma

Intranasal delivery of a monoclonal IgG1 antibody targeting mugwort pollen protected mice from allergic rhinitis and asthma symptoms, without lowering systemic IgE levels. This localized, non-invasive approach dampened Th2 inflammation and preserved healthy airway tissue in sensitized mice.

14 Jul 2025