Allergy News and Research

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The term allergy encompasses a wide range of conditions; it is not a disease in itself. In 1906 Clemens von Pirquet was the first to describe allergies as a changed or altered reaction of the immune system in response to exposure to foreign proteins. These days the term allergy – medically termed hypersensitivity, signifies an exaggerated reaction to foreign substances.

Authenticated mast cells successfully developed from hematopoietic stem cells

Mast cells are critically involved in immunity and immune disorders. However, they are rarely cultured ex vivo for experimental manipulation because of the difficulty in isolating useful numbers and limitations related to 2D culture.

20 Sep 2019

New 'Idiopathic Anaphylaxis Yardstick' offers guidance for diagnosis and treatment

Many people in danger of the severe allergic reaction known as anaphylaxis understand exactly what they need to avoid to stay safe.

18 Sep 2019

Ticks now carrying multiple diseases, says new study

A new study published in the journal mBio reports that ticks carry many more disease-causing agents than just those responsible for causing Lyme disease.

17 Sep 2019

No more tears: immunization without needles

A new study published in the Journal of Investigative Dermatology reports a novel skin vaccine patch which could help effective and safe immunization by disrupting the permeability of the skin, providing a convenient and non-invasive alternative to immunization shots. This innovative technique now needs to be tested in humans.

17 Sep 2019

Simple genetic test may boost response rates in children with eosinophilic esophagitis

Personalized medicine - where the proper medicine and proper dose are used for the individual patient - moved a step closer to reality for children suffering from eosinophilic esophagitis, an inflammation of the food pipe often caused by an allergic reaction to certain foods.

12 Sep 2019

Long-term antibiotic use in preemies promotes drug-resistant gut bacteria

Very preterm infants are often sick and require antibiotic treatment to save their lives. However, when this form of therapy lasts for 20 months or more, it may affect the gut microbiome over the long-term in addition to its acute effects.

10 Sep 2019

NIAID experts call for innovative research on STIs

Sexually transmitted infections, or STIs, pose a significant public health challenge. Globally, more than one million new STI cases are diagnosed each day.

10 Sep 2019

Microbiome loss from antibiotic use affects response to flu vaccine

Every living person has trillions of microbes living in their digestive tract, and more than 400 species of bacteria in the gut, more than the number of cells in the body. The normal gut flora is important to maintain eubiosis, the microbial balance in the body.

9 Sep 2019

Oral antibiotics that kill gut microorganisms can alter immune response to flu vaccines

The normal human gut microbiome is a flourishing community of microorganisms, some of which can affect the human immune system. In a new paper published this week in Cell, researchers found that oral antibiotics, which can kill gut microorganisms, can alter the human immune response to seasonal influenza vaccination.

8 Sep 2019

FDA approves first drug to treat patients with rare lung condition

The U.S. Food and Drug Administration today approved Ofev (nintedanib) capsules to slow the rate of decline in pulmonary function in adults with interstitial lung disease associated with systemic sclerosis or scleroderma, called SSc-ILD. It is the first FDA-approved treatment for this rare lung condition.

7 Sep 2019

Individuals with more allergic diseases have higher asthma risk

A Finnish study found that the more allergic diseases an individual has, the higher the asthma risk.

6 Sep 2019

Genetics may play a role in allergic reactions to contrast media

Researchers in South Korea have found that patients with family and personal history of allergic reactions to contrast media are at risk for future reactions, according to a large study published in the journal Radiology.

4 Sep 2019

Danish-American researchers find new way to treat chronic inflammation

Researchers from Aarhus University Hospital and Aarhus University in Denmark in collaboration with researchers from Colorado in the United States have found a new way to treat the inflammation involved in chronic diseases such as psoriasis, asthma and HIV.

30 Aug 2019

First-of-its-kind study shows two out of three Danes suffer from chronic conditions

The world's first mapping of an entire country's chronic diseases shows that approximately two out of three Danes over the age of 16 have one or more chronic conditions. This is nearly twice the previous estimates from Danish authorities.

27 Aug 2019

Nab-Paclitaxel drug combo reduces risk of breast cancer recurrence

A recent large German study has shown that a new combination therapy for breast cancer treatment leads to a lowered risk of the disease coming back. A commentary on this landmark clinical trial has been published in the latest issue of the Journal of Clinical Oncology by the researchers Masey Ross and Charles Geyer Jr. from the VCU Massey Cancer Center. The commentary was titled, “Nab-Paclitaxel: A New Standard of Care in Neoadjuvant Therapy of High-Risk Early Breast Cancer?”

27 Aug 2019

Combination therapy for rheumatoid arthritis may lead to higher remission rates

Researchers at the University of North Carolina Chapel Hill and RTI International, a nonprofit research institute, recently found that patients with early rheumatoid arthritis (RA) may see less disease activity and higher remission rates after biologic therapy plus methotrexate (MTX) rather than either treatment alone.

22 Aug 2019

Meat allergy triggered by tick bites explained

Researchers from University of Virginia School of Medicine have uncovered the mystery behind development of allergic reactions to red meat such as beef in some individuals. Recently there has been a body of research on allergies to meat developing in individuals due to tick bites.

21 Aug 2019

'As-needed' treatment OK for children with mild asthma

Children with mild asthma may use two inhalers – one steroid and the other a bronchodilator, when symptoms occur, a new study shows.

19 Aug 2019

FDA approves novel device to treat symptoms associated with advanced heart failure

The U.S. Food and Drug Administration today approved the Barostim Neo System for the improvement of symptoms in patients with advanced heart failure who are not suited for treatment with other heart failure devices, such as cardiac resynchronization therapy.

18 Aug 2019

Scientists step closer to an Ebola cure

The Ebola virus has killed thousands of people in Western Africa between 2014 and 2016. Recently, another outbreak in Congo emerged, killing roughly a thousand people. Now, scientists are a step closer to an Ebola cure, thanks to two new drugs that appear to be highly effective in treating people with the virus.

13 Aug 2019