Brain News and Research

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The human brain is the center of the human nervous system and is a highly complex organ. Enclosed in the cranium, it has the same general structure as the brains of other mammals, but is over three times as large as the brain of a typical mammal with an equivalent body size.

Mapping the brain’s wiring changes from birth to old age

Researchers mapped brain topology changes across the lifespan, identifying four critical turning points that shape neural networks from childhood to aging.

27 Nov 2025

Chronic drinking weakens the blood-brain barrier through the gut

Chronic alcohol consumption disrupts the blood-brain barrier, but Faecalibacterium prausnitzii shows promise in repairing this damage and improving cognition.

27 Nov 2025

Cognitive blocks drive the brain's advantage over AI

Artificial intelligence may write award-winning essays and diagnose disease with remarkable accuracy, but biological brains still hold the upper hand in at least one crucial domain: flexibility.

27 Nov 2025

New AI models detect dementia with high accuracy using EEG signals

Researchers at örebro University have developed two new AI models that can analyze the brain's electrical activity and accurately distinguish between healthy individuals and patients with dementia, including Alzheimer's disease.

27 Nov 2025

Polyphenol-rich dietary patterns linked to lower cardiovascular disease risk

People who regularly consume polyphenol-rich foods and drinks, such as tea, coffee, berries, cocoa, nuts, whole grains and olive oil, may have better long-term heart health.

27 Nov 2025

Driving behavior data may help detect early cognitive decline

Using in-vehicle driving data may be a new way to identify people who are at risk of cognitive decline, according to a study published on November 26, 2025, in Neurology, the medical journal of the American Academy of Neurology.

26 Nov 2025

Experimental drug engasertib shows promise for treating inherited bleeding disorder

Hereditary hemorrhagic telangiectasia (HHT) is the second most common inherited bleeding disorder worldwide, affecting 1 in 3,800 persons.

26 Nov 2025

Comprehensive research identifies most effective ADHD treatments

The most comprehensive review to date of ADHD treatments has found that medication for children and adults, and cognitive behavioral therapy for adults, remain the most effective approaches, backed by the strongest short-term trial evidence.

26 Nov 2025

Researchers uncover how a key transcription factor reads DNA in human cells

With a new study in the journal Cell, researchers at Stanford University and Stockholm University have contributed to increased knowledge about gene regulation in human cells.

26 Nov 2025

Rare inherited variants shape risk and outcomes in pediatric brain and spinal cord tumors

Researchers at Children's Hospital of Philadelphia (CHOP) and Children's National Hospital in Washington D.C. are uncovering how rare inherited genetic variants contribute to the development of brain and spinal cord tumors in children.

26 Nov 2025

UBQLN2 liquid droplets emerge as key catalysts of early α-synuclein aggregation

Parkinson's disease (PD) is an age-related, progressive neurodegenerative disorder. The hallmark of PD pathogenesis is the Lewy bodies (LBs) that accumulate in neurons in the substantia nigra region of the brain, damaging these neurons and leading to the motor symptoms of the disease.

26 Nov 2025

Using a psychedelic to explore the relationship between alpha waves and self-awareness

When people use a psychedelic called dimethyltryptamine (DMT), they experience a temporary loss of their sense of self. DMT interacts with a frequency of brain activity associated with self-referential processes (alpha waves), but it's unclear how this activity relates to self-awareness.

26 Nov 2025

Shared genetic roots between delirium and Alzheimer’s disease

This study reveals genetic and proteomic risk factors for delirium, offering insights into its etiology and potential biomarkers for prediction and prevention.

26 Nov 2025

Researchers discover new mutation hotspot in the human genome

Researchers have discovered new regions of the human genome particularly vulnerable to mutations. These altered stretches of DNA can be passed down to future generations and are important for how we study genetics and disease.

26 Nov 2025

Head trauma impairs brain waste clearance in professional fighters

The brain's waste-clearing system significantly declines in function with repeated head impacts, according to a new study of cognitively impaired professional boxers and mixed martial arts fighters. The findings will be presented next week at the annual meeting of the Radiological Society of North America.

26 Nov 2025

African statisticians provide new insights into malaria prevention

University of the Witwatersrand - Edson Mwebesa, Fellow at the Wits-based Sub-Saharan Africa Advanced Consortium for Biostatistics (SSACAB), knows children who died from late-diagnosed malaria. His research has also revealed that malaria is more prevalent in pregnant Ugandan women than in any other population.

25 Nov 2025

Poor lung gas exchange may help explain lingering brain symptoms in Long COVID

This study found that people with Long COVID more than two years after infection showed normal lung tests and brain structure, yet reported significant sleep and cognitive symptoms. Subtle correlations revealed that poorer lung gas exchange was linked with higher brain perfusion, worse sleep, and weaker executive function, suggesting a possible lung–brain connection.

25 Nov 2025

Obesity-related metabolic stress may affect brain health far earlier than expected

For decades, scientists have known that what harms the body often harms the brain. Conditions such as obesity, high blood pressure and insulin resistance strain the body's vascular and metabolic systems.

25 Nov 2025

Early treatment after head injury lowers long-term risk of Alzheimer’s disease

Getting treatment within one week of a serious head injury can reduce the risk of developing Alzheimer's disease by up to 41%, according to new research from Case Western Reserve University.

25 Nov 2025

White matter alterations connect coronary artery disease to cognitive decline

Individuals with coronary artery disease (CAD) - a constricting or blocking of blood vessels feeding the heart - face increased risks of strokes, cognitive impairment and dementia. However, the link between CAD and cognitive function is not fully understood.

25 Nov 2025