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Industry & academia combine to support synthesis of squaric acid monoamides as building blocks for drug discovery

Asynt have collaborated with Kingston University and Key Organics to develop an accessible new synthetic compound library.

From Asynt 5 Nov 2023

State-by-state snapshot: Long-COVID's grip varies, with mental health in the crosshairs

Study shows 14% of Americans face long-COVID with variations across states and ethnicities, linking it to significant declines in physical and mental health.

5 Nov 2023

Butterfly-inspired imaging sensor can detect cancer cells with high accuracy

There are many creatures on our planet with more advanced senses than humans. Turtles can sense Earth's magnetic field. Mantis shrimp can detect polarized light.

3 Nov 2023

Citrus compounds show zesty promise in type 2 diabetes management

Citrus compounds show promise in type 2 diabetes management, reducing blood glucose and mitigating metabolic complications without a clear threshold in humans for bioflavonoid efficacy.

2 Nov 2023

Marijuana-like compound shows promise as new treatment for skin lupus

A marijuana-like compound holds out promise as a new treatment for a severe autoimmune skin disease called skin lupus, according to a study published recently by a multicenter team including researchers at the George Washington University.

2 Nov 2023

The development of a machine-learned scoring function of human preference in the context of early drug discovery campaigns

In a recent study published in Nature Communications, researchers developed a scoring mechanism based on artificial intelligence for early drug discovery campaigns that might be utilized for compound prioritizing, motif rationalization, and biased drug design.

1 Nov 2023

From Cells to Drugs: How Cell Painting is Transforming Drug Discovery

In this interview, Jordi Carreras delves into the fascinating world of Cell Painting, a powerful technology gaining momentum in drug discovery. He shares insights into his groundbreaking research, the unique aspects of Phenaros' drug discovery platform, and the synergy between academia and industry.

From ELRIG (UK) Ltd. 1 Nov 2023

Moringa-infused gluten-free sourdough offers health boost for all, especially celiacs

Researchers have developed a gluten-free sourdough bread fortified with Moringa oleifera, an unconventional crop known for its health benefits. The study found that this novel bread formulation offers enhanced nutritional content, including higher levels of protein and essential minerals, making it a viable option for people with celiac disease and those seeking healthier bread alternatives.

30 Oct 2023

Receptor structure-based virtual screening identifies a promising p38α inhibitor

Announcing a new publication for Acta Materia Medica journal. Mitogen-activated protein kinases (MAPKs) are a group of serine-threonine protein kinases that can be activated by extracellular stimuli.

27 Oct 2023

AI-designed drug candidate shows promise for gastric acid inhibition

Researchers at Nagoya University in Japan created and improved artificial intelligence (AI) designs to synthesize a candidate compound for a new gastric acid inhibitor with a better binding affinity than existing drugs.

26 Oct 2023

New study challenges long-held belief about how chemotherapy works

A new study from the University of Wisconsin–Madison suggests that chemotherapy may not be reaching its full potential, in part because researchers and doctors have long misunderstood how some of the most common cancer drugs actually ward off tumors.

26 Oct 2023

Somatic mutations in the skin not responsible for the start or spread of psoriasis

Psoriasis -; a chronic skin condition -; is not caused or spread by spontaneous genetic mutations in the skin, new research suggests.

26 Oct 2023

In acute myocardial infarction patients, does adding a traditional Chinese medicine compound to standard treatments improve outcomes?

Researchers investigated whether Tongxinluo, a Chinese medicinal compound, could improve clinical outcomes among ST-segment elevation myocardial infarction patients.

26 Oct 2023

Newly identified small molecule can suppress growth of breast and ovarian cancers in animal models

Researchers at Baylor College of Medicine have identified a small molecule named 5D4 that can suppress the growth of breast and ovarian cancers in animal models.

25 Oct 2023

Scientists develop new method to control brain activity with light

Studying the brain remains one of the most challenging endeavors in neuroscience. Researchers have explored various methods for live imaging and stimulation of deep brain activity.

25 Oct 2023

Marijuana's psychoactive compound may alter brain wiring in adolescents

In a mouse study designed to explore the impact of marijuana's major psychoactive compound, THC, on teenage brains, Johns Hopkins Medicine researchers say they found changes to the structure of microglia, which are specialized brain immune cells, that may worsen a genetic predisposition to schizophrenia.

25 Oct 2023

Could duck fats be a healthier alternative to saturated fats?

A recent study explores the potential benefits of utilizing duck fats in the food industry, highlighting their unique fatty acid composition and improved properties compared to vegetable oils. Duck fats offer a healthier alternative to saturated fats, making them a valuable resource for enhancing food products.

22 Oct 2023

Low serotonin levels observed in long COVID and other viral infections

Researchers identify a pathophysiological mechanism linking serotonin reduction to the multifaceted etiology of post-acute sequelae of COVID-19.

20 Oct 2023

Potato starch supplement may help prevent gvhd in bone marrow transplant patients

Researchers at Baylor College of Medicine and the University of Michigan conducted a phase I pilot study to assess the feasibility of using potato starch as a dietary intervention to modify the gut microbiome in bone marrow transplant patients.

19 Oct 2023

MuTaLig: A multi-target paradigm for innovative drug discoveries

Everyone at some point in their life may need to take medication to treat an illness or disease. By finding new and better ways to create drugs, the COST Action Multi-target paradigm for innovative ligand identification in the drug discovery process (MuTaLig) helped improve the effectiveness and safety of the medications, which can ultimately benefit people's health and well-being.

19 Oct 2023

Compound News and Research

Industry & academia combine to support synthesis of squaric acid monoamides as building blocks for drug discovery

State-by-state snapshot: Long-COVID's grip varies, with mental health in the crosshairs

Butterfly-inspired imaging sensor can detect cancer cells with high accuracy

Citrus compounds show zesty promise in type 2 diabetes management

Marijuana-like compound shows promise as new treatment for skin lupus

The development of a machine-learned scoring function of human preference in the context of early drug discovery campaigns

From Cells to Drugs: How Cell Painting is Transforming Drug Discovery

Moringa-infused gluten-free sourdough offers health boost for all, especially celiacs

Receptor structure-based virtual screening identifies a promising p38α inhibitor

AI-designed drug candidate shows promise for gastric acid inhibition

New study challenges long-held belief about how chemotherapy works

Somatic mutations in the skin not responsible for the start or spread of psoriasis

In acute myocardial infarction patients, does adding a traditional Chinese medicine compound to standard treatments improve outcomes?

Newly identified small molecule can suppress growth of breast and ovarian cancers in animal models

Scientists develop new method to control brain activity with light

Marijuana's psychoactive compound may alter brain wiring in adolescents

Could duck fats be a healthier alternative to saturated fats?

Low serotonin levels observed in long COVID and other viral infections

Potato starch supplement may help prevent gvhd in bone marrow transplant patients

MuTaLig: A multi-target paradigm for innovative drug discoveries

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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