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The human brain is the center of the human nervous system and is a highly complex organ. Enclosed in the cranium, it has the same general structure as the brains of other mammals, but is over three times as large as the brain of a typical mammal with an equivalent body size.

Hypertension may induce early gene expression changes in brain cells

Hypertension impairs blood vessels, neurons and white matter in the brain well before the condition causes a measurable rise in blood pressure, according to a new preclinical study from Weill Cornell Medicine investigators.

14 Nov 2025

New insights into glioblastoma survival linked to brain fluid dynamics

Glioblastoma-the most aggressive form of brain cancer-remains one of medicine's biggest challenges. Despite surgery, radiotherapy, and chemotherapy, most patients survive only about a year after diagnosis.

14 Nov 2025

Mental navigation framework helps people change pathological thinking

The stereotypical image of psychotherapy shows a patient lying on a couch, exploring their deepest traumas. This leads to awareness of unconscious habits, thoughts, and drives and has long been a cornerstone of psychotherapy.

14 Nov 2025

Magnetic microrobots guide drugs directly to blood clots

Every year, 12 million people worldwide suffer a stroke; many die or are permanently impaired. Currently, drugs are administered to dissolve the thrombus that blocks the blood vessel.

14 Nov 2025

Study unites global neuroscientists to share brain data

Imagine if every neuroscientist in the world could suddenly speak the same language and share their discoveries instantly. Allen Institute researchers and engineers have now unlocked that potential and the vast discoveries it could lead to through the new Brain Knowledge Platform (BKP).

14 Nov 2025

New study reveals how the uterus senses force to drive labor

When labor begins, the uterus must coordinate rhythmic, well-timed contractions to deliver the baby safely.

13 Nov 2025

Machine learning model boosts success of liver transplants from circulatory death donors

There are more candidates on the waitlist for a liver transplant than there are available organs, yet about half the time a match is found with a donor who dies after cardiac arrest following the removal of life support, the transplant must be canceled.

13 Nov 2025

How soccer fandom rewires the brain

Studying brain patterns in soccer fans, researchers found that certain circuit regions of the brain were activated while viewing soccer matches involving their favorite team, triggering positive and negative emotions and behaviors, according to a new study published today in Radiology, a journal of the Radiological Society of North America (RSNA).

13 Nov 2025

Pig kidney transplant breakthrough uncovers immune rejection secrets

Researchers have uncovered and then overcome an obstacle that has led to the failure of pioneering efforts in xenotransplantation, in which an animal kidney is transplanted into a human.

13 Nov 2025

Underweight children face higher risk of stopping ADHD medication early

Children who are underweight are more likely to stop taking their ADHD medication within a year. These are the findings of a study conducted at the University of Gothenburg on methylphenidate, a common pharmacological treatment in ADHD.

13 Nov 2025

Study reveals the effectiveness of Painimation in decoding pain for sickle cell patients

Pain is a constant, complex companion that clinicians often struggle to understand and measure for people living with sickle cell disease. Traditional pain scales reduce this deeply personal experience to a single number that is often inaccurate.

13 Nov 2025

Empowering early detection of dementia with a dual approach involving AI and patient input

Few primary care practices are designed for the timely detection of Alzheimer's disease and related dementias. The limited time that primary care clinicians are able to spend with patients, the need to focus on the health problems which brought the patient to the clinic, as well as the stigma of Alzheimer's disease and dementia are major reasons for lack of recognition of the condition.

13 Nov 2025

Early lean mass shapes long-term brain development in preterm infants

Extremely preterm infants with higher fat-free mass at term-equivalent age show better cognitive, language, and motor outcomes through age three. Early lean-tissue growth offers stronger neurodevelopmental insight than traditional growth measures.

12 Nov 2025

Income and social disparities found to influence dementia risk factors

People with lower incomes and people from racial and ethnic historically underrepresented groups in clinical studies are more likely to have modifiable risk factors for dementia, factors that could be changed to lower their risk, according to a study published November 12, 2025, in Neurology, the medical journal of the American Academy of Neurology.

12 Nov 2025

New Mayo Clinic tool predicts Alzheimer’s risk years before symptoms begin

Mayo Clinic researchers have developed a new tool that can estimate a person's risk of developing memory and thinking problems associated with Alzheimer's disease years before symptoms appear.

12 Nov 2025

Switching APOE4 to APOE2 in adult mice reduces Alzheimer’s pathology and improves memory

Replacing APOE4 with APOE2 in adult mice rapidly reshapes brain lipids and gene expression, even after development is complete. This switch, especially when targeted to astrocytes, reduces amyloid burden, dampens gliosis, and improves associative memory despite E2-like peripheral lipid risks.

12 Nov 2025