Brain News and Research

RSS

The human brain is the center of the human nervous system and is a highly complex organ. Enclosed in the cranium, it has the same general structure as the brains of other mammals, but is over three times as large as the brain of a typical mammal with an equivalent body size.

Alzheimer’s breakthrough reveals how tweaking one gene shields brain connections

Lowering the transcription factor PU.1 reprograms microglia into a neuroprotective, lymphoid-like state that compacts amyloid, blocks tau spread, and preserves synapses in Alzheimer’s disease. Microglial CD28 signaling helps restrain inflammation, revealing a regulatory switch that may inform future immunotherapies targeting microglia rather than neurons.

6 Nov 2025

Low-dose THC mitigates harmful side effects and inflammation caused by HIV treatment

Long-term, low doses of THC mitigate many harmful side effects and inflammation caused by HIV and antiretroviral therapy (ART), according to new research from Texas Biomedical Research Institute.

6 Nov 2025

Scientists map kinesin-2 tail structure to understand cargo binding

For decades, scientists have known that motor proteins like kinesin-2 ferry vital cargo along microtubule "highways" inside cells. But how these molecular vehicles identify and bind to the right cargo remained a mystery. The new study provides a key piece of this puzzle by revealing the atomic-level structure of the kinesin-2 tail and its interaction with cargo and adaptor proteins.

6 Nov 2025

5,000 steps a day may slow Alzheimer’s-related brain changes

Regular walking is linked to slower cognitive decline in older adults, emphasizing its role in delaying Alzheimer’s disease and enhancing memory retention.

6 Nov 2025

Researchers identify patient response patterns to novel schizophrenia medication

Each year, about 100,000 Americans experience psychosis, a serious condition that disrupts thoughts and perceptions so profoundly that it can distort a person's sense of reality.

6 Nov 2025

Farmers, barbers, and GOP lawmakers grapple with the fate of ACA tax credits

John Cleveland is ready to pay a lot more for his health insurance next year.

6 Nov 2025

Longevity gene offers clues to extending life without restrictive diets

The pursuit of a longer life may currently be trending for tech bros, but the notion of a fountain of youth, or even immortality, has intrigued people for millennia.

6 Nov 2025

Heart damage during middle age linked to greater dementia risk in later life

People with signs of damage to their heart during middle age are more likely to develop dementia in later life, according to a new study led by UCL (University College London) researchers.

5 Nov 2025

Newly identified microglia subtype offers protection against Alzheimer’s disease

In Alzheimer's disease, the leading cause of dementia, microglia-the brain's immune defenders-can act as both protectors and aggressors, shaping how the disease progresses.

5 Nov 2025

Bleeding strokes strike earlier and harder in heavy drinkers

People who drink heavily may have bleeding strokes a decade earlier than people who are not heavy drinkers, according to a study published November 5, 2025, in Neurology®, an official journal of the American Academy of Neurology.

5 Nov 2025

Heart attack in older adults linked to higher risk of late-onset epilepsy

Older adults who have a heart attack may be more likely to develop epilepsy later in life, according to a study published November 5, 2025 in Neurology®, the medical journal of the American Academy of Neurology.

5 Nov 2025

Heavy drinking linked to earlier and more severe brain bleeds

A new study by investigators from Mass General Brigham suggests that heavy alcohol use may lead to more severe brain bleeds and cause long-term brain vessel damage at a younger age.

5 Nov 2025

New analysis identifies safer treatment paths for children with medulloblastoma

By analyzing data from three clinical trials treating children with the brain tumor medulloblastoma, scientists at St. Jude Children's Research Hospital have designed an approach to safely reduce therapy, thereby lowering side effects.

5 Nov 2025

Aggression and self-harm could share a common neural basis

Aggression and self-harm often co-occur in individuals with a history of early-life trauma-a connection that has largely been documented by self-reporting in research and clinical settings.

5 Nov 2025

How gut microbes shape sleep: New review reveals microbiome clues to insomnia and apnea

A new Brain Medicine review maps how gut microbes influence sleep disorders, from insomnia and sleep apnea to circadian disruption, via bile acids, neurotransmitters, and immune pathways. The findings highlight gut-driven targets for improving sleep quality through diet, probiotics, and microbiome modulation.

5 Nov 2025

New AI-assisted atlas can help visualize the human brain in unprecedented detail

A new AI-assisted brain atlas that can help visualize the human brain in unprecedented detail has been developed by UCL researchers, in a major step forward for neuroscience and neuroimaging.

5 Nov 2025

Opioid receptors caught in motion offering clues for safer painkillers

Scientists have known for decades that opioids relieve pain by binding to molecular switches in the brain called mu-opioid (pronounced "mew-opioid") receptors. What they didn't know - until now - was exactly what happens next.

5 Nov 2025

Do gut microbes cause autism? New research says diet plays the bigger role

In a family-based study, researchers found that children with autism spectrum disorder (ASD) shared similar gut microbiomes with their relatives but showed distinctly different eating habits. Their preference for sweets and limited vegetable intake suggests behavior-driven dietary choices may influence, rather than result from, microbiome differences.

5 Nov 2025

Researchers discover why living in a deprived neighborhood may raise dementia risk

Cambridge researchers have discovered why living in a disadvantaged neighbourhood may be linked to an increase in an individual's risk of dementia.

5 Nov 2025

Study sheds light on how Alzheimer's disease may contribute to larger health issues

A recent study from Houston Methodist sheds light on how Alzheimer's disease may contribute to larger health issues by hijacking the body's ability to regulate its metabolism.

5 Nov 2025

Brain News and Research

Further Reading

Alzheimer’s breakthrough reveals how tweaking one gene shields brain connections

Low-dose THC mitigates harmful side effects and inflammation caused by HIV treatment

Scientists map kinesin-2 tail structure to understand cargo binding

5,000 steps a day may slow Alzheimer’s-related brain changes

Researchers identify patient response patterns to novel schizophrenia medication

Farmers, barbers, and GOP lawmakers grapple with the fate of ACA tax credits

Longevity gene offers clues to extending life without restrictive diets

Heart damage during middle age linked to greater dementia risk in later life

Newly identified microglia subtype offers protection against Alzheimer’s disease

Bleeding strokes strike earlier and harder in heavy drinkers

Heart attack in older adults linked to higher risk of late-onset epilepsy

Heavy drinking linked to earlier and more severe brain bleeds

New analysis identifies safer treatment paths for children with medulloblastoma

Aggression and self-harm could share a common neural basis

How gut microbes shape sleep: New review reveals microbiome clues to insomnia and apnea

New AI-assisted atlas can help visualize the human brain in unprecedented detail

Opioid receptors caught in motion offering clues for safer painkillers

Do gut microbes cause autism? New research says diet plays the bigger role

Researchers discover why living in a deprived neighborhood may raise dementia risk

Study sheds light on how Alzheimer's disease may contribute to larger health issues

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News