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Novel protein construct prevents lethal COVID-19 in mice

Researchers in the United States have developed a novel protein that prevented lethal disease among mice infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

16 Mar 2021

Using new neurotechnology techniques to improve treatment of brain disorders

Two FET projects - HERMES and STARDUST - aim to improve the treatment of widespread brain disorders such as Parkinson's and epilepsy by developing and adopting the latest neurotechnology techniques: "biohybrid neuronics" and "in-vivo optogenetics".

16 Mar 2021

Clinical trial begins to evaluate SENSE device’s ability to monitor intracranial hemorrhage

Sense Diagnostics, a medical technology company focused on improving outcomes for stroke and brain injury patients, announced the initiation of a multicenter pivotal trial to evaluate the safety and efficacy of a non-invasive brain scanner to monitor intracranial hemorrhage in an acute hospital setting.

16 Mar 2021

Researchers develop near-infrared light triggered drug delivery system

A new concept of on-demand drug delivery system has emerged in which the drugs are automatically released from in vivo medical devices simply by shining light on the skin.

15 Mar 2021

Dual-action monoclonal antibodies from an original SARS survivor show promise against COVID-19

A recent study, currently available on the bioRxiv preprint server, indicates that a pair of dual-action monoclonal antibodies derived from an original 2003 SARS survivors could play an important role in the fight against coronavirus disease 2019 (COVID-19) due to their broadly neutralizing activity and the engagement of the immune system via effector function capabilities.

14 Mar 2021

Texas Biomed receives DoD subcontracts to assess SARS-CoV-2 decontamination technologies

Texas Biomedical Research Institute received two Department of Defense's (DoD) Defense Health Agency subcontracts to assess the efficacy of surface coating and aerosolized decontamination technologies to combat SARS-CoV-2 and other respiratory pathogens on surfaces and in the air.

11 Mar 2021

NIAID awards $2.5 million in grants to support research on bacteriophage therapy

The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, has awarded $2.5 million in grants to 12 institutes around the world to support research on bacteriophage therapy.

11 Mar 2021

Study: Graphene nanoparticles interfere with the development of anxiety-related behaviors in vertebrates

New research shows that the nanomaterial acts on the excitatory synapses, interfering with the development of anxiety related behaviors in vertebrates.

11 Mar 2021

Researchers confirm new drug development route for treating multiple sclerosis, asthma

Brazilian researchers who study a native venomous fish have confirmed a route to drug development for the treatment of chronic inflammatory diseases such as multiple sclerosis and asthma.

10 Mar 2021

SARS-CoV-2 variants rapidly arise in non-human hosts, potential risk for human reinfection

The study, published on the preprint server bioRxiv*, highlights the need to study viral evolution and pathogenesis in human and animal hosts. This could help prevent future outbreaks that may mimic the magnitude of the current COVID-19 pandemic.

9 Mar 2021

Energy-efficient, long-lasting pressure sensing device for monitoring patient health

Recent advances in technology have opened many possibilities for using wearable and implantable sensors to monitor various indicators of patient health.

9 Mar 2021

Researchers explore 3D printing materials to print realistic aorta models

Personalized 3D printed models created from cardiac imaging data, mainly from cardiac CT images have been increasingly used in cardiovascular disease, primarily in the preoperative planning and simulation of complex surgical procedures, as well as medical education.

8 Mar 2021

Researchers establish organoid culture models from prostate tumor biopsies

Scientists at Urology Research Laboratory of the Department for BioMedical Research, University of Bern and Urology Department of the Inselspital of Bern, have established organoid culture models from prostate tumor biopsies.

8 Mar 2021

Study rethinks the role of ACE2 in SARS-CoV-2 viral entry

Researchers in the US recently infected a series of human lung and head/neck cancer cell lines with SARS-CoV-2 that expressed varying levels of ACE2 and the TMPRSS2 protease to reassess their role in viral entrance.

8 Mar 2021

Researchers identify new molecular mechanisms in chronic skin inflammation

Frequently occurring chronic skin inflammation like in atopic dermatitis (AD or neurodermatitis) and psoriasis have different causes such as genetic predisposition, stress or allergens.

5 Mar 2021

A SARS-CoV-2 spike protein adjuvant vaccine candidate produces durable rapid protection in vivo

A recent study reports the safety and high efficacy of an adjuvanted vaccine candidate against SARS-CoV-2 and the complications of COVID-19.

5 Mar 2021

Study shows lower antibody cross-reactivity after infection with the B.1.1.7 SARS-CoV-2 variant

In a recent research paper currently available on the bioRxiv* preprint server, a diverse group of researchers has examined the immunogenicity of antibodies against the variant B.1.1.7 of the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) initially found in the United Kingdom – and revealed diminished recognition and neutralization of either parental strains or the South African variant.

3 Mar 2021

Researchers develop ultrapotent miniproteins that target SARS-CoV-2 receptor-binding domain

Researchers have investigated the effectiveness of a bioengineered miniprotein in protecting against SARS-CoV-2 infection in vivo. The researchers evaluated the miniprotein, LCB1, against SARS-CoV-2-mediated lung disease in human ACE2-expressing transgenic mice.

3 Mar 2021

Obesity may reduce COVID-19 vaccine efficacy, say researchers

A startling indicates that obesity may reduce the immune response to the current COVID-19 vaccines, along with other factors like age and sex. This could have significant implications for vaccination strategies in obese people.

3 Mar 2021

Novel SARS-CoV-2 spike vaccine candidate produces strong neutralizing response in vivo

A new study by researchers at Mahidol University in Bangkok, Thailand, reports a COVID-19 vaccine candidate called HexaPro in producing neutralizing antibodies against the SARS-CoV-2 spike protein in an animal model.

3 Mar 2021

in vivo News and Research

Novel protein construct prevents lethal COVID-19 in mice

Using new neurotechnology techniques to improve treatment of brain disorders

Clinical trial begins to evaluate SENSE device’s ability to monitor intracranial hemorrhage

Researchers develop near-infrared light triggered drug delivery system

Dual-action monoclonal antibodies from an original SARS survivor show promise against COVID-19

Texas Biomed receives DoD subcontracts to assess SARS-CoV-2 decontamination technologies

NIAID awards $2.5 million in grants to support research on bacteriophage therapy

Study: Graphene nanoparticles interfere with the development of anxiety-related behaviors in vertebrates

Researchers confirm new drug development route for treating multiple sclerosis, asthma

SARS-CoV-2 variants rapidly arise in non-human hosts, potential risk for human reinfection

Energy-efficient, long-lasting pressure sensing device for monitoring patient health

Researchers explore 3D printing materials to print realistic aorta models

Researchers establish organoid culture models from prostate tumor biopsies

Study rethinks the role of ACE2 in SARS-CoV-2 viral entry

Researchers identify new molecular mechanisms in chronic skin inflammation

A SARS-CoV-2 spike protein adjuvant vaccine candidate produces durable rapid protection in vivo

Study shows lower antibody cross-reactivity after infection with the B.1.1.7 SARS-CoV-2 variant

Researchers develop ultrapotent miniproteins that target SARS-CoV-2 receptor-binding domain

Obesity may reduce COVID-19 vaccine efficacy, say researchers

Novel SARS-CoV-2 spike vaccine candidate produces strong neutralizing response in vivo

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

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The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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