Bioinformatics News and Research

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Bioinformatics is the application of information techniques for the storage, retrieval, and analysis of large quantities of biological data.

Discovery could pave the way for developing therapies to treat nonalcoholic steatohepatitis

UT Southwestern immunologists have uncovered a key pathogenic event prompted by obesity that can trigger severe forms of nonalcoholic fatty liver disease and potential liver failure.

27 Dec 2022

New methods can advance the development of rapid diagnostics for many infectious diseases

Two companion studies report new artificial intelligence approaches for identification of molecular "fingerprints" for specific infections. The methods, used here to derive a fingerprint for COVID-19, can advance the development of rapid diagnostics for many infectious diseases.

21 Dec 2022

Comprehensive lung cell atlas offers insights into an unexpected immune niche in the airways

The most comprehensive lung cell atlas to date, from the Wellcome Sanger Institute and collaborators, has revealed 11 new lung cell types and offers detailed insight into an immune process involved in fighting lung infections.

21 Dec 2022

New mutations near known genes could contribute to the increase in cleft lip and palate risk

Cleft lip and palate are among the most common congenital malformations, which are mainly due to genetic causes.

16 Dec 2022

Study reveals subtypes and EBV-associated regulatory epigenome reprogramming in nasopharyngeal carcinoma

Researchers from the Department of Clinical Oncology, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong (HKUMed) discovered a novel subtype of Epstein-Barr Virus (EBV)-positive nasopharyngeal carcinoma (NPC) and EBV-associated immunosuppression in the tumor microenvironment (TME).

16 Dec 2022

Next-generation sequencing could change research on sexual assault cases

In this interview, Alexis Garloff talks to NewsMedical about her next-generation sequencing research and the possible applications in forensics, particularly in sexual assault cases.

From Verogen, Inc. 16 Dec 2022

Ceramide blockers prevent the loss of muscle mass during aging in mice

During aging, mice, like humans, become inactive and lose muscle mass and strength. A team of scientists led by Johan Auwerx at EPFL have now discovered that when mice age, their muscles become packed with ceramides.

16 Dec 2022

Assessing clinical adoption of 2017 guidelines for interpretation and reporting of sequence variants in cancer

The Association for Molecular Pathology (AMP), the premier global molecular diagnostic professional society, has published a report that was designed to assess clinical adoption, identify classification inconsistencies, and evaluate implementation barriers for the 2017 report, "Standards and Guidelines for the Interpretation and Reporting of Sequence Variants in Cancer: A Joint Consensus Recommendation of the Association for Molecular Pathology, American Society of Clinical Oncology, and College of American Pathologists.

15 Dec 2022

UBC researchers identify a compound that shows early promise at halting viral infections

Researchers at UBC's Life Sciences Institute have identified a compound that shows early promise at halting infections from a range of coronaviruses, including all variants of SARS-CoV-2 and the common cold.

15 Dec 2022

Severity of COVID-19 in men may be due to the loss of Y chromosome

Men are at an increased risk of a severe bout of COVID-19 compared to women. Researchers at Uppsala University have now shown that this may be due to loss of the Y chromosome in part of their white blood cells.

14 Dec 2022

Bioinformatics approach for the design of siRNAs against SARS-CoV-2

Scientists have developed a set of siRNAs against SARS-CoV-2 using computational approaches.

14 Dec 2022

U-M leads multi-university partnership that aims to predict cognitive fatigue in individuals

Researchers at the University of Michigan are leading a multi-university partnership that aims to understand and predict cognitive fatigue in individuals.

13 Dec 2022

New spatial cell atlas of the developing human lung identifies 144 cell states

The developing human lung has been mapped in unprecedented detail, identifying 144 cell states in the early stages of life, and uncovering new links between developmental cells and lung cancer.

8 Dec 2022

BGI Genomics and the University of Pécs launch a joint laboratory in Hungary

On November 29, 2022, BGI Genomics and the University of Pécs (UP) agreed to launch a joint laboratory in Hungary.

6 Dec 2022

Co-infecting pathogens and the microbiome from SARS-CoV-2 positive and negative samples

Researchers evaluated co-infections in SARS-CoV-2-infected patients.

6 Dec 2022

Study predicts persistent cross-species SARS-CoV-2 variant infectivity

Scientists believe bats first transmitted SARS-CoV-2 to humans in December 2019, and while the virus has since evolved into several variants such as delta and omicron, a new study indicates the virus is still highly transmissible between mammals.

5 Dec 2022

Research project obtains nearly seven million to study factors that affect human immune system in early life

The first few months and years of life are crucial to the development of the human immune system. This is an important phase as the immune system can define which diseases individuals might develop later in life.

2 Dec 2022

Integrated approach addresses some of the biggest challenges in natural products drug discovery

Many successful drugs have their origins in natural sources such as plants, fungi, and bacteria, but screening natural products to identify potential drugs remains a difficult undertaking.

1 Dec 2022

New guidelines for designing synthetic molecules that block interaction between two proteins

Inside cells, proteins constantly interact with each other to carry out different functions. For some diseases in which these functions are altered, blocking the binding between two or more proteins emerges as a possible therapeutic approach.

30 Nov 2022

Duke researchers find human DNA sequence divergence after split from common ancestor of chimpanzees

A team of Duke researchers has identified a group of human DNA sequences driving changes in brain development, digestion and immunity that seem to have evolved rapidly after our family line split from that of the chimpanzees, but before we split with the Neanderthals.

24 Nov 2022

Bioinformatics News and Research

Further Reading

Discovery could pave the way for developing therapies to treat nonalcoholic steatohepatitis

New methods can advance the development of rapid diagnostics for many infectious diseases

Comprehensive lung cell atlas offers insights into an unexpected immune niche in the airways

New mutations near known genes could contribute to the increase in cleft lip and palate risk

Study reveals subtypes and EBV-associated regulatory epigenome reprogramming in nasopharyngeal carcinoma

Next-generation sequencing could change research on sexual assault cases

Ceramide blockers prevent the loss of muscle mass during aging in mice

Assessing clinical adoption of 2017 guidelines for interpretation and reporting of sequence variants in cancer

UBC researchers identify a compound that shows early promise at halting viral infections

Severity of COVID-19 in men may be due to the loss of Y chromosome

Bioinformatics approach for the design of siRNAs against SARS-CoV-2

U-M leads multi-university partnership that aims to predict cognitive fatigue in individuals

New spatial cell atlas of the developing human lung identifies 144 cell states

BGI Genomics and the University of Pécs launch a joint laboratory in Hungary

Co-infecting pathogens and the microbiome from SARS-CoV-2 positive and negative samples

Study predicts persistent cross-species SARS-CoV-2 variant infectivity

Research project obtains nearly seven million to study factors that affect human immune system in early life

Integrated approach addresses some of the biggest challenges in natural products drug discovery

New guidelines for designing synthetic molecules that block interaction between two proteins

Duke researchers find human DNA sequence divergence after split from common ancestor of chimpanzees

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