Cell Death News and Research

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Innate immunity and metabolic stress drive a unique form of cell death

In several disease conditions, including infections and cancers, innate immune activation and nutrient scarcity occur together.

1 Dec 2025

UTEP scientists find promising new target in the fight against high-grade serous carcinoma

Scientists at The University of Texas at El Paso have found a promising new target in the fight against high-grade serous carcinoma, an aggressive form of ovarian cancer.

1 Dec 2025

Triaptosis-based therapeutic innovations could offer renewed hope for cancer patients

Cancer remains one of the most critical global public health challenges, exerting profound social, economic, and clinical burdens while limiting gains in human life expectancy.

1 Dec 2025

Tiny metal particles can kill cancer cells while leaving healthy cells unharmed

An international research team led by RMIT University have created tiny particles, known as nanodots, made from a metallic compound that can kill cancer cells while leaving healthy cells largely unharmed.

1 Dec 2025

Drug combination can bypass cellular defenses in neuroblastoma

A discovery from Australian researchers could lead to better treatment for children with neuroblastoma, a cancer that currently claims 9 out of 10 young patients who experience recurrence.

29 Nov 2025

Tattoo ink alters immune cells and weakens some vaccine responses

New research shows tattoo pigments migrate to lymph nodes, causing inflammation and altering immune responses to vaccines, with potential health risks.

27 Nov 2025

Scientists uncover how brain enzyme OTULIN controls tau expression

Scientists have uncovered a surprising mechanism by which a brain enzyme called OTULIN controls the expression of tau, the protein that forms toxic tangles in Alzheimer's disease.

25 Nov 2025

New research questions reliability of macaque models for TIGIT-targeted cancer treatments

A new study published in the Journal of Biological Chemistry from UC Davis Comprehensive Cancer Center finds that TIGIT, an immune checkpoint receptor targeted by cancer immunotherapy drugs, triggers a different response in rhesus macaques compared to humans.

24 Nov 2025

Calcium-activated switch improves delivery and potency of cancer-fighting drugs

Cancer-fighting antibody drugs are designed to penetrate tumor cells and release a lethal payload deep within, but too often they don't make it that far.

24 Nov 2025

New insights into ribosome collisions and stress response

LMU researchers uncover the mechanism by which ribosomes raise alarms in the cell.

24 Nov 2025

New method can stop or reverse the decline of cellular energy production

Biomedical researchers at Texas A&M University may have discovered a way to stop or even reverse the decline of cellular energy production - a finding that could have revolutionary effects across medicine.

22 Nov 2025

Inflammation control can protect against AMD-like retinal damage

University of Minnesota Medical School researchers have shown that reducing chronic inflammation can significantly protect against age-related macular degeneration (AMD)-like pathology in preclinical models.

21 Nov 2025

Inflammatory biomarkers offer new insights for precision medicine in ischemic stroke

Ischemic stroke, a leading cause of disability and mortality worldwide, is a complex cerebrovascular event with outcomes heavily influenced by the inflammatory response.

20 Nov 2025

Cancer cells hijack cell death enzyme to regrow after treatment

The emergence of cancer drug resistance remains one of the most pressing problems in cancer care and there is a critical need to devise approaches to mitigate it.

19 Nov 2025

New antibody strategy shows promise for halting cyst growth in polycystic kidney disease

Polycystic kidney disease (PKD) is a debilitating hereditary condition in which fluid-filled sacs form and proliferate in the kidneys. Over time, the painful, growing cysts rob the organs of their function, often leading to dialysis in advanced cases.

18 Nov 2025

Enhancing the cancer-immunity cycle through innovative vaccines

Therapeutic cancer vaccines have experienced a remarkable resurgence over the past decade, representing a paradigm shift in oncology toward harnessing the immune system's intrinsic ability to combat malignancies.

14 Nov 2025

Lymphoma resistance mechanisms and future therapies

A new review was published in Volume 12 of Oncoscience on October 13, 2025, titled "Targeted therapies and resistance mechanisms in lymphoma: Current landscape and emerging solutions."

13 Nov 2025

Innovative research reveals FGD3 as a key player in breast cancer cell death

A naturally occurring protein that tends to be expressed at higher levels in breast cancer cells boosts the effectiveness of some anticancer agents, including doxorubicin, one of the most widely used chemotherapies, and a preclinical drug known as ErSO, researchers report.

13 Nov 2025

Breakthrough in bone regeneration using nanoparticle-stem cell hybrid

A research team in South Korea has successfully developed a novel technology that combines nanoparticles with stem cells to significantly improve 3D bone tissue regeneration.

12 Nov 2025

GLP-1 drugs linked to improved survival in colon cancer patients

A new University of California San Diego study offers compelling evidence that glucagon-like peptide-1 (GLP-1) receptor agonists - the class of drugs behind Ozempic, Wegovy and Mounjaro, for example - may do more than regulate blood sugar and weight.

11 Nov 2025