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Engineered herpes virus activates potent immune responses against glioblastoma

Researchers at Mass General Brigham have modified a herpes simplex virus (HSV-1) that stimulates the immune system to attack glioblastoma cells.

4 Dec 2025

Cystic fibrosis patients on triple-drug therapy can safely reduce daily lung treatments

A new multi-site study led by researchers at CU Anschutz shows that people with cystic fibrosis (CF) who start the triple-drug therapy elexacaftor/tezacaftor/ivacaftor (ETI) can safely reduce many of their daily lung treatments while maintaining good health for years.

4 Dec 2025

Scientists uncover why SETX-deficient cancer cells rely on error-prone DNA repair

The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break-when both sides of the DNA helix are cut at once.

4 Dec 2025

Researchers capture high-resolution footage of flu viruses entering human cells

For the first time, researchers have observed live and in high resolution how influenza viruses infect living cells. This was possible thanks to a new microscopy technique, which could now help to develop antiviral therapies in a more targeted manner.

4 Dec 2025

New C-COMPASS software opens spatial proteomics and lipidomics to non-coders

A new tool developed by Helmholtz Munich and the German Center for Diabetes Research and the University of Bonn makes spatial proteomics and lipidomics easier to use – no coding required.

4 Dec 2025

University of Iowa research finds an effective therapy for rare kidney disease in children

A rare and life-threatening kidney disease in children finally has an effective therapy, thanks in large part to pioneering research and clinical leadership from University of Iowa Health Care Stead Family Children's Hospital.

4 Dec 2025

Injectable scaffold vaccine shows strong protection against implant-related MRSA

Research reveals that silica scaffolds can train the immune system against S. aureus, offering a novel approach to prevent orthopedic device infections.

4 Dec 2025

Sweat testing could transform drug monitoring and diabetes care

Innovative sweat sampling techniques could revolutionize diagnostics, offering insights into glucose levels and environmental toxins with minimal discomfort.

4 Dec 2025

TRIMTECH Therapeutics appoints Alison Lawton as Chair of the Board

TRIMTECH Therapeutics, a biotechnology company developing novel small molecule therapies that target and degrade protein aggregates associated with neurodegenerative diseases, today announced the appointment of Alison Lawton as Chair of its Board of Directors.

From TRIMTECH Therapeutics 4 Dec 2025

New rapid test distinguishes real HIV infections from vaccine-related false positives

Since the human immunodeficiency virus (HIV) was identified in 1983, roughly 91.4 million people around the world have contracted the virus and an additional 44.1 million have died from related causes.

3 Dec 2025

Purdue technology explored as a potential tool to identify women at higher risk of preeclampsia

A researcher in Purdue University's Weldon School of Biomedical Engineering is participating in a two-year research study evaluating approaches to monitor the health of pregnant women in Africa and inform future efforts to reduce maternal mortality.

3 Dec 2025

Sugar alcohol sorbitol may increase the risk of developing steatotic liver disease

Sweeteners such as aspartame, found in Equal packets, sucralose (Splenda), or sugar alcohols are often seen as healthier alternatives to food with refined sugar (glucose).

3 Dec 2025

Prehabilitation helps reduce disability after surgery in frail older adults

A large clinical trial published in JAMA Surgery shows that prehabilitation (also called prehab) can reduce disability after surgery in older adults with frailty, provided they are able to fully take part in the prehab program.

3 Dec 2025

Breast cancer reshapes lymphatic vessels to support its spread

Breast cancer is able to modify the lymphatic vessels through which it travels to the draining lymph nodes. From there, it can then spread to other parts of the body.

3 Dec 2025

Human gene maps show widespread gaps in non-European representation

Human gene maps contain major blind spots because they were built largely from the DNA sequences of people with European ancestry, according to a study published today in Nature Communications.

3 Dec 2025

Insect flour could boost gut health and cut environmental impact

Chitin-rich insect flours show promise as functional foods, boosting beneficial gut bacteria while addressing allergenicity and consumer trust issues.

3 Dec 2025

Microbial warning signs that predict death risk in severe pneumonia

Researchers examine the gut and lung microbiota of severe community-acquired pneumonia patients.

3 Dec 2025

AI model ranks genetic variants from severe to mild disease mutations

popEVE combines evolutionary insights with human population data to identify damaging genetic mutations, improving variant scoring for rare diseases.

3 Dec 2025

New method reveals how human cells initiate DNA replication

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular ageing, cancer, and genetic disorders. Therefore, understanding how cells replicate their DNA is crucial for elucidating fundamental biological processes, diseases, and even evolution.

3 Dec 2025

DNA language model performance hinges on pre-training data choices

Researchers at The University of Texas MD Anderson Cancer Center have performed a comprehensive evaluation of five artificial intelligence (AI) models trained on genomic sequences, known as DNA foundation language models.

3 Dec 2025