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Study maps HER2 mutations in lung cancer patients from Northeastern Brazil

A new research paper was published in Volume 16 of Oncotarget on June 17, 2025, titled "Molecular landscape of HER2-mutated non-small cell lung cancer in Northeastern Brazil: Clinical, histopathological, and genomic insights."

27 Jun 2025

Caloric restriction may help delay decline in reproductive function associated with aging

A new research paper was published in Aging (Aging-US) Volume 17, Issue 5, on May 20, 2025, titled "Short-term moderate caloric restriction in the rhesus macaque attenuates markers of ovarian aging in select populations."

24 Jun 2025

Utah State biologist investigates chromosomal changes driving evolution

How do living things evolve? What is the myriad of processes by which generic variations in a population affect organisms' survival and allow reproduction in an ever-changing environment?

19 Jun 2025

Global guideline released by WHO on managing sickle cell disease in pregnancy

The World Health Organization (WHO) today released its first-ever global guideline on the management of sickle cell disease (SCD) during pregnancy, addressing a critical and growing health challenge that can have life-threatening consequences for both women and babies.

19 Jun 2025

Oxytocin stimulates pancreatic hormones to improve insulin secretion

A new research paper was published in Aging (Aging-US) Volume 17, Issue 5, on May 1, 2025, titled "Oxytocin modulates insulin and GLP-1 secretion in pancreatic islets."

18 Jun 2025

Rare pancreatic cancer patients show remarkable outcomes with immunotherapy

A new research paper was published in Volume 16 of Oncotarget on June 10, 2025, titled "Exceptional responders to immunotherapy in pancreatic cancer: A multi-institutional case series of a rare occurrence."

17 Jun 2025

Rare ovarian tumor found during postmenopausal surgery for pelvic organ prolapse

A new case report was published in Volume 12 of Oncoscience on May 22, 2025, titled "A rare case: Pure Sertoli cell tumor uncovered in atrophic ovary during postmenopausal vault prolapse evaluation."

13 Jun 2025

APOE gene variants influence metabolic patterns linked to aging and Alzheimer’s risk

A new research paper was published in Aging (Aging-US) Volume 17, Issue 5, on May 3, 2025, titled "APOE genotype and biological age impact inter-omic associations related to bioenergetics."

12 Jun 2025

Difficult childhood experiences linked to increased risk of endometriosis later in life

A new study from Karolinska Institutet involving over a million women links difficult childhood experiences to the risk of being diagnosed with endometriosis later in life.

11 Jun 2025

ISSCR updates guidelines for oversight and regulation of stem cell-based embryo models

The International Society for Stem Cell Research (ISSCR) Embryo Models Working Group has released updated recommendations for the oversight and regulation of stem cell-based embryo models (SCBEM), aiming to address rapid advancements and ensure responsible scientific progress.

11 Jun 2025

Methylation clocks may mislead anti-aging therapy evaluation

A new research perspective was published in Aging (Aging-US) Volume 17, Issue 5, on May 5, 2025, titled "Methylation clocks for evaluation of anti-aging interventions."

10 Jun 2025

Patient-derived xenograft models may become an indispensable tool in precision oncology

Cancer remains one of the most pressing global health challenges, with millions of new diagnoses each year. While precision medicine and targeted therapies have transformed treatment strategies, many patients still face drug resistance and disease recurrence.

10 Jun 2025

Overexpression of two long non-coding RNAs identified in gastric cancer

A new research paper was published in Volume 16 of Genes & Cancer on May 9, 2025, titled "Evaluation of LncRNAs CBR3-AS1 and PCA3 expression in Gastric cancer and their correlation to clinicopathological variables."

6 Jun 2025

Reverse transcriptase activity found in aging and Alzheimer’s brains

Alzheimer's disease is the most common cause of dementia and affects more than a tenth of Americans aged 65 and older.

5 Jun 2025

Rethinking healthcare through the science of aging

A new editorial was published in Aging (Aging-US) Volume 17, Issue 5, on May 29, 2025, titled "Rethinking healthcare through aging biology."

4 Jun 2025

Aging increases brain vulnerability to mild hypoxia and blood-brain barrier disruption

A new research paper was published in Aging (Aging-US) on May 1, 2025, as the cover of Volume 17, Issue 5, titled "Defining the hypoxic thresholds that trigger blood-brain barrier disruption: the effect of age."

3 Jun 2025

Yeast cells offer promising alternative for manufacturing DNase1

The protein DNase1 is one of the oldest biological agents in history: It has been on the market since 1958 and is now used, among other things, to treat cystic fibrosis.

28 May 2025

Targeting individual frailty traits may prevent falls among the elderly

A new research paper was published in Aging (Aging-US) Volume 17, Issue 4, on April 1, 2025, titled "Examining frailty phenotypes of community-dwelling older adults in Taiwan using the falls risk for older people in the community – Taiwan version (Tw-FROP-Com)."

23 May 2025

Rare cancer gene found in sperm donor sparks European regulatory concerns

A case in which a sperm donor was later found to be carrying a cancer-causing pathogenic variant in his gametes has highlighted the problems of regulating gamete donation at European and international level, the annual conference of the European Society of Human Genetics will hear today (Saturday).

23 May 2025

Detecting balance impairments early could prevent life-threatening falls

As we get older, our bodies stop performing as they once did. We aren't as strong as we once were, we don't see as well as we used to and we start becoming less mobile.

23 May 2025

Reproduction News and Research

Study maps HER2 mutations in lung cancer patients from Northeastern Brazil

Caloric restriction may help delay decline in reproductive function associated with aging

Utah State biologist investigates chromosomal changes driving evolution

Global guideline released by WHO on managing sickle cell disease in pregnancy

Oxytocin stimulates pancreatic hormones to improve insulin secretion

Rare pancreatic cancer patients show remarkable outcomes with immunotherapy

Rare ovarian tumor found during postmenopausal surgery for pelvic organ prolapse

APOE gene variants influence metabolic patterns linked to aging and Alzheimer’s risk

Difficult childhood experiences linked to increased risk of endometriosis later in life

ISSCR updates guidelines for oversight and regulation of stem cell-based embryo models

Methylation clocks may mislead anti-aging therapy evaluation

Patient-derived xenograft models may become an indispensable tool in precision oncology

Overexpression of two long non-coding RNAs identified in gastric cancer

Reverse transcriptase activity found in aging and Alzheimer’s brains

Rethinking healthcare through the science of aging

Aging increases brain vulnerability to mild hypoxia and blood-brain barrier disruption

Yeast cells offer promising alternative for manufacturing DNase1

Targeting individual frailty traits may prevent falls among the elderly

Rare cancer gene found in sperm donor sparks European regulatory concerns

Detecting balance impairments early could prevent life-threatening falls

What to know about prostate cancer eBook

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