Allergy News and Research

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The term allergy encompasses a wide range of conditions; it is not a disease in itself. In 1906 Clemens von Pirquet was the first to describe allergies as a changed or altered reaction of the immune system in response to exposure to foreign proteins. These days the term allergy – medically termed hypersensitivity, signifies an exaggerated reaction to foreign substances.

Human ‘common cold’ virus kills healthy chimpanzees in Uganda

In the wild, chimpanzees face any number of dire threats, ranging from poachers to predators to deforestation.

13 Dec 2017

First short-acting ‘follow-on’ insulin receives FDA approval to treat diabetes

The U.S. Food and Drug Administration today approved Admelog (insulin lispro injection), a short-acting insulin indicated to improve control in blood sugar levels in adults and pediatric patients aged 3 years and older with type 1 diabetes mellitus and adults with type 2 diabetes mellitus.

12 Dec 2017

Researchers discover potential regulator essential for killer T cells to reside in tumors

Researchers report the discovery that a protein called "Runx3" programs killer T cells to establish residence in tumors and infection sites.

11 Dec 2017

New tests offer better chance for more accurate detection of Lyme disease

New tests to detect early Lyme disease - which is increasing beyond the summer months -could replace existing tests that often do not clearly identify the infection before health problems occur.

7 Dec 2017

BU researchers receive $2.7 million grant to find better ways of delivering anti-retrovirals

Rahm Gummuluru, PhD, associate professor of microbiology at Boston University School of Medicine, and Bjoern Reinhard, PhD, professor of chemistry at Boston University, have been awarded a Research Project Grant from the National Institutes of Allergy and Infectious Diseases/National Institute of Health.

5 Dec 2017

Children with high blood levels of polyunsaturated fatty acids less likely to develop asthma or rhinitis

New research from Karolinska Institutet in Sweden reveals that high levels of polyunsaturated fatty acids in children's blood are associated with a reduced risk of asthma or rhinitis at the age of 16 years. The study is published in The Journal of Allergy and Clinical Immunology.

5 Dec 2017

Study uncovers genes that drive peanut allergy reactions

Mount Sinai researchers have identified six genes that activate hundreds of other genes in children experiencing severe allergic reactions to peanuts.

5 Dec 2017

Investigational ZPIV vaccine found to be safe and immunogenic in trial participants

The investigational Zika purified inactivated virus (ZPIV) vaccine was well-tolerated and induced an immune response in participants, according to initial results from three Phase 1 clinical trials.

5 Dec 2017

Study suggests novel approach to predict respiratory allergy in children

A new study in EBioMedicine by researchers at Karolinska Institutet in Sweden and the Medical University of Vienna, Austria suggests that immune response in early childhood to a handful of allergen molecules can predict the onset of allergic rhinitis and asthma in adolescence.

4 Dec 2017

States — and 9m kids — ‘in a bind’ as Congress dawdles on CHIP funding

Last week, Colorado became the first state to notify families that children who receive health insurance through the Children’s Health Insurance Program are in danger of losing their coverage.

4 Dec 2017

Intestinal worms have influence on allergy and asthma risk in humans

While young people with parasite worms currently have four times higher risk for developing allergies and asthma than others. Their parents are generally unaffected.

4 Dec 2017

FDA grants approval to first biosimilar for treatment of patients with breast, stomach cancers

The U.S. Food and Drug Administration today approved Ogivri (trastuzumab-dkst) as a biosimilar to Herceptin (trastuzumab) for the treatment of patients with breast or metastatic stomach cancer (gastric or gastroesophageal junction adenocarcinoma) whose tumors overexpress the HER2 gene (HER2+).

4 Dec 2017

Study identifies new role for stress receptor CRF1 expressed on mast cells

A new study published online in the Journal of Leukocyte Biology provides new insight into how stress, through signaling of corticotropin-releasing factor (CRF), interacts with cells in the immune system to cause disease.

1 Dec 2017

Experts offer research strategies to yield more protective flu vaccine candidates

In a New England Journal of Medicine perspective, experts from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, and the World Health Organization Collaborating Centre for Reference and Research on Influenza in Melbourne discuss how the process of preparing seasonal influenza vaccines in eggs may contribute to their limited effectiveness.

30 Nov 2017

NICE releases the latest asthma management standards

In 2016 in England and Wales alone, a shocking 1,237 people died from an asthma attack2.

From Bedfont® Scientific Ltd 29 Nov 2017

Study provides potential explanation for increased prevalence of asthma in adult women

In childhood, asthma is more common in boys than girls. But around the time of puberty, that picture reverses. By midlife women are twice as likely as men to have asthma.

29 Nov 2017

Inexplicable cases of anaphylaxis caused by uncommon red meat allergy, study finds

While rare, some people experience recurrent episodes of anaphylaxis--a life-threatening allergic reaction that causes symptoms such as the constriction of airways and a dangerous drop in blood pressure--for which the triggers are never identified.

28 Nov 2017

Scientists detect pathological prion protein in skin of CJD patients

Researchers have found that it was possible to detect abnormal prion protein in the skin of 23 people who died from Creutzfeldt-Jakob Disease (CJD). They also found that exposing mice to skin tissue taken from the CJD patients caused them to develop prion disease.

23 Nov 2017

Got food allergies? Add milk to the worries for your meal

Since her son Matt was an infant, Lynda Mitchell knew he had a milk allergy. She controlled the symptoms by switching his baby formula. But when he was 1, Halloween proved horrifying. While trick-or-treating in a pumpkin costume, Matt grabbed a chocolate bar and bit through the wrapper. Although he spit out the candy, his violent allergic reaction morphed into a mess of hives, swelling and labored breathing. He ended up in the emergency room.

22 Nov 2017

New analysis identifies five distinct patient clusters that may need different approaches to manage asthma

New data analysis from the Mundipharma International Limited sponsored REALISE survey (REcognize Asthma and LInk to Symptoms and Experiences), published today in the Journal of Allergy and Clinical Immunology: In Practice has identified different patient groups sharing common attitudes towards asthma and its management.

22 Nov 2017

Allergy News and Research

Further Reading

Human ‘common cold’ virus kills healthy chimpanzees in Uganda

First short-acting ‘follow-on’ insulin receives FDA approval to treat diabetes

Researchers discover potential regulator essential for killer T cells to reside in tumors

New tests offer better chance for more accurate detection of Lyme disease

BU researchers receive $2.7 million grant to find better ways of delivering anti-retrovirals

Children with high blood levels of polyunsaturated fatty acids less likely to develop asthma or rhinitis

Study uncovers genes that drive peanut allergy reactions

Investigational ZPIV vaccine found to be safe and immunogenic in trial participants

Study suggests novel approach to predict respiratory allergy in children

States — and 9m kids — ‘in a bind’ as Congress dawdles on CHIP funding

Intestinal worms have influence on allergy and asthma risk in humans

FDA grants approval to first biosimilar for treatment of patients with breast, stomach cancers

Study identifies new role for stress receptor CRF1 expressed on mast cells

Experts offer research strategies to yield more protective flu vaccine candidates

NICE releases the latest asthma management standards

Study provides potential explanation for increased prevalence of asthma in adult women

Inexplicable cases of anaphylaxis caused by uncommon red meat allergy, study finds

Scientists detect pathological prion protein in skin of CJD patients

Got food allergies? Add milk to the worries for your meal

New analysis identifies five distinct patient clusters that may need different approaches to manage asthma

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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