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Brain scans reveal hidden clues to depression susceptibility

By repeatedly scanning the brains of a small group of patients for a year and a half, Weill Cornell Medicine researchers have identified a distinct pattern of neuronal interactions that appears to predispose some people to developing depression.

4 Sep 2024

Novel intermediate form of serotonin receptor identified as therapeutic target for psychiatric disorders

Misha Kudryshev's lab at the Max Delbrück Center has identified a molecular intermediate of a serotonin receptor that is involved in diseases such as depression and schizophrenia.

4 Sep 2024

Does air pollution drive dementia?

Chronic air pollution exposure is a key factor in dementia development, with pollutants like PM2.5 and NO2 linked to cognitive decline and neurodegeneration.

4 Sep 2024

Alirocumab reduces dangerous coronary plaque and stabilizes high-risk lesions

Intensive LDL-C lowering with alirocumab significantly reduces high-risk coronary plaque burden, transforming unstable plaques into more stable phenotypes. This lesion-level analysis underscores the enhanced efficacy compared to vessel-level approaches.

4 Sep 2024

Study reveals ChatGPT-4 Vision's strengths and weaknesses in radiology exam performance

Researchers evaluating the performance of ChatGPT-4 Vision found that the model performed well on text-based radiology exam questions but struggled to answer image-related questions accurately.

3 Sep 2024

New learning technique enhances detection and prediction of adolescent mental health disorders

The majority of mental health disorders manifest during adolescence and relate to a multiplex interplay of neurobiological and environmental factors.

3 Sep 2024

Major trial to test multiple drugs for progressive supranuclear palsy

A clinical trial that will test three drugs concurrently, and could include more, represents new hope for patients with progressive supranuclear palsy (PSP), an incurable neurodegenerative disorder that usually kills within seven years after symptoms start.

3 Sep 2024

New protocol explores the combination of aerobic exercise and cognitive rehabilitation for MS patients

Researchers at Kessler Foundation have published a new clinical protocol examining the combination of aerobic exercise and cognitive rehabilitation to improve learning and memory in individuals with multiple sclerosis (MS) who have mobility disability.

3 Sep 2024

Researchers develop stable compound for targeted alpha therapy in prostate cancer

Compounds containing astatine-211 (211At) can be used in targeted radiotherapies for prostate cancer, but deastatination in the body remains a significant hurdle.

3 Sep 2024

Extraordinary cell division mechanism discovered in common dental plaque bacteria

One of the most diverse ecosystems on the planet is closer than you think - right inside your mouth. Your mouth is a thriving ecosystem of more than 500 different species of bacteria living in distinct, structured communities called biofilms.

2 Sep 2024

Clonal hematopoiesis drives femoral atherosclerosis in middle-aged adults

Researchers reveal that clonal hematopoiesis (CH) significantly increases the risk of developing femoral atherosclerosis, suggesting a unidirectional relationship independent of traditional cardiovascular risk factors.

2 Sep 2024

Study finds higher heart attack risk days after cold exposure

Hospital admissions for heart attacks increase after exposure to lower air temperature and cold spells, according to a study published today in JACC, the flagship journal of the American College of Cardiology, and presented at the European Society of Cardiology (ESC) Congress 2024.

1 Sep 2024

American football head impacts tied to increased brain damage and cognitive decline

Repetitive head impacts in former American football players are linked to increased perivascular space volume, which correlates with cognitive decline and neurodegeneration. The study suggests that the force of head impacts may be more critical than frequency, with potential protective effects from β-blocker use.

1 Sep 2024

Clonal hematopoiesis identified as new risk factor for atherosclerosis

To the known risk factors for cardiovascular disease - high blood pressure, high cholesterol, diabetes, overweight and obesity, smoking, and physical inactivity - a new one has to be added: clonal hematopoiesis.

30 Aug 2024

New imaging technology enhances detection of tumor remnants

The imaging techniques currently used in biological research cannot penetrate into deeper tissue layers.

30 Aug 2024

New ESC guidelines highlight broader approach to managing chronic coronary syndromes

The 2024 ESC Guidelines on the management of chronic coronary syndromes (CCS) include a focus on both larger and smaller blood vessels of the heart; new models to estimate chances of blocked large arteries (so-called obstructive coronary artery disease); optimal selection and sequence of tests; drugs and interventions to prevent disease complications and improve symptoms, and the fundamental role of patient involvement.

30 Aug 2024

Semaglutide lowers COVID-19-related deaths in cardiovascular patients with obesity

Semaglutide, the popular anti-obesity drug, reduced the rates of COVID-19-related adverse events, including death, in those who had overweight or obesity and established cardiovascular disease without diabetes, according to a new study published in JACC, the flagship journal of the American College of Cardiology.

30 Aug 2024

New ESC guidelines integrate management of aortic and peripheral arterial diseases

The 2024 ESC Guidelines for the management of peripheral arterial and aortic diseases (PAAD) evaluate these vascular diseases together as part of same cardiovascular system, appreciating that patients with aortic diseases are at risk of having peripheral vascular diseases and vice versa.

30 Aug 2024

Carcinotech dominates summer awards season

Over the past six years, Carcinotech has been laser-focused on developing, optimising and commercializing our innovative drug development platform.

From Carcinotech 30 Aug 2024

Fibrin fuels thromboinflammation and brain damage in COVID-19

Researchers reveal fibrin's critical role in COVID-19 by driving thromboinflammation and neuropathology, and highlight a potential antibody therapy to mitigate these effects.

29 Aug 2024

Imaging News and Research

Brain scans reveal hidden clues to depression susceptibility

Novel intermediate form of serotonin receptor identified as therapeutic target for psychiatric disorders

Does air pollution drive dementia?

Alirocumab reduces dangerous coronary plaque and stabilizes high-risk lesions

Study reveals ChatGPT-4 Vision's strengths and weaknesses in radiology exam performance

New learning technique enhances detection and prediction of adolescent mental health disorders

Major trial to test multiple drugs for progressive supranuclear palsy

New protocol explores the combination of aerobic exercise and cognitive rehabilitation for MS patients

Researchers develop stable compound for targeted alpha therapy in prostate cancer

Extraordinary cell division mechanism discovered in common dental plaque bacteria

Clonal hematopoiesis drives femoral atherosclerosis in middle-aged adults

Study finds higher heart attack risk days after cold exposure

American football head impacts tied to increased brain damage and cognitive decline

Clonal hematopoiesis identified as new risk factor for atherosclerosis

New imaging technology enhances detection of tumor remnants

New ESC guidelines highlight broader approach to managing chronic coronary syndromes

Semaglutide lowers COVID-19-related deaths in cardiovascular patients with obesity

New ESC guidelines integrate management of aortic and peripheral arterial diseases

Carcinotech dominates summer awards season

Fibrin fuels thromboinflammation and brain damage in COVID-19

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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