Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Efficacy of SARS-CoV2 variant-specific replicating RNA vaccines on SARS-CoV-2 variants of concern

A new study evaluates the repRNA vaccine expressing the SARS-CoV-2 spike protein for the B.1.1.7 and B.1.351 variants in mice and hamsters.

19 Dec 2021

Antibody-like proteins derived from sharks may be used to combat future SARS outbreaks

Small, unique antibody-like proteins known as VNARs - derived from the immune systems of sharks - can prevent the virus that causes COVID-19, its variants, and related coronaviruses from infecting human cells, according to a new study published Dec. 16.

16 Dec 2021

Engineering of brain-mimetic injectable hydrogel scaffolds with self-healing properties

A team of scientists bioengineered a physiologically relevant, brain mimetic 3D scaffold for culturing neuronal cells.

15 Dec 2021

TP53 mutations in men may predispose to aggressive prostate cancer

Men who have mutations in a gene called TP53 have a high risk of developing aggressive prostate cancer, a multicenter research team in the United States has found.

11 Dec 2021

Maternal and neonatal cord-blood antibody profile in response to SARS-CoV-2

The goal of the current research was to determine the profile and specificity of maternal serum and neonatal cord blood antibody responses to SARS-CoV-2 virus exposure in mothers.

10 Dec 2021

Analysis finds substantially more mutations in the omicron SARS-CoV-2 variant

A University of Florida Health researcher has successfully analyzed the many mutations in the omicron variant of the SARS-CoV-2 virus, a crucial step in better understanding the variant's potential threat and ways to combat it.

9 Dec 2021

Johns Hopkins astrophysicist receives Life Sciences 2021 award for novel cancer mapping technology

Johns Hopkins astrophysicist, Alexander Szalay, Ph.D., and Kimmel Cancer Center pathologist Janis Taube, M.D., M.Sc., received a Life Sciences 2021 award for AstroPath at this year's Falling Walls Science Summit, an international event honoring research breakthroughs from across the globe.

9 Dec 2021

Study of individuals referred to a cardiovascular disease clinic designed for patients with long COVID

Scientists discuss the characteristics, diagnostic evaluations, and cardiac diagnoses in patients referred to a clinic designed for patients with PASC.

9 Dec 2021

Study identifies several proteins that protect against disease development

Inflammatory processes are associated with a large range of human diseases, including rheumatic diseases and allergies. Protein biomarkers are measurable molecules that can have a prognostic value in patients, be used to diagnose disease, or indicate severity of disease.

8 Dec 2021

New projects aim to identify new solutions to combat antimicrobial-resistant infections

Researchers at Washington University School of Medicine in St. Louis will lead projects aimed at identifying new solutions to help prevent antimicrobial-resistant infections and their spread.

8 Dec 2021

Hypercoagulability of the blood responsible for cardiac thrombosis in COVID-19 patients

Researchers examined autopsy tissue samples of hearts from patients who died early in the COVID-19 pandemic.

7 Dec 2021

New approach to enhance the therapeutic efficacy of liver cancer immunotherapy

In recent years, tumor immunotherapy has emerged as a highly promising and much-touted oncological approach.

7 Dec 2021

Lunaphore highlights novel spatial biology research at SITC 2021

Lunaphore today announced new research from collaborators at the University of Birmingham.

From Lunaphore 7 Dec 2021

Lunaphore to host inaugural Spatial Biology Week™ virtual meeting

Lunaphore today announced the events and activities planned around the inaugural Lunaphore Spatial Biology Week™, taking place virtually December 6-10, 2021.

From Lunaphore 7 Dec 2021

SARS-CoV-2 virus-like particles elicit potent neutralizing antibody response in variant challenge

Researchers develop a virus-like particle for SARS-CoV-2 based on the co-expression of the spike, membrane, and envelope structural proteins.

6 Dec 2021

Probiotics significantly improve the symptoms of pregnancy-related problems

In a first-of-its-kind study, researchers at the UC Davis School of Medicine found that probiotics significantly improve the symptoms of pregnancy-related nausea, vomiting and constipation. The findings were published in the journal Nutrients.

6 Dec 2021

Targeting the brain should be the focus of ALS therapy, not just spinal cord

The brain is indeed a target for treating ALS (amyotrophic lateral sclerosis), Northwestern Medicine scientists have discovered.

4 Dec 2021

Penn researchers illuminate key molecular details of T-cell exhaustion process

Specially engineered immune cells called CAR T cells have proven themselves to be a powerful weapon against blood cancers, but against solid tumors they are much less effective, due in part to a process called T-cell exhaustion.

2 Dec 2021

Study documents and visualizes hearing loss-associated genes in the inner ear

Researchers from Uppsala University have been able to document and visualise hearing loss-associated genes in the human inner ear, in a unique collaboration study between otosurgeons and geneticists.

2 Dec 2021

SARS-CoV-2 evolution in animals could provide insights on the mutability of COVID-19

When animals catch COVID-19 from humans, new SARS-CoV-2 variants can arise. To evaluate this phenomenon, an interdisciplinary team at the College of Veterinary Medicine and Biomedical Sciences systematically analyzed mutation types occurring in the virus after infection of cats, dogs, ferrets, and hamsters.

2 Dec 2021

Pathology News and Research

Further Reading

Efficacy of SARS-CoV2 variant-specific replicating RNA vaccines on SARS-CoV-2 variants of concern

Antibody-like proteins derived from sharks may be used to combat future SARS outbreaks

Engineering of brain-mimetic injectable hydrogel scaffolds with self-healing properties

TP53 mutations in men may predispose to aggressive prostate cancer

Maternal and neonatal cord-blood antibody profile in response to SARS-CoV-2

Analysis finds substantially more mutations in the omicron SARS-CoV-2 variant

Johns Hopkins astrophysicist receives Life Sciences 2021 award for novel cancer mapping technology

Study of individuals referred to a cardiovascular disease clinic designed for patients with long COVID

Study identifies several proteins that protect against disease development

New projects aim to identify new solutions to combat antimicrobial-resistant infections

Hypercoagulability of the blood responsible for cardiac thrombosis in COVID-19 patients

New approach to enhance the therapeutic efficacy of liver cancer immunotherapy

Lunaphore highlights novel spatial biology research at SITC 2021

Lunaphore to host inaugural Spatial Biology Week™ virtual meeting

SARS-CoV-2 virus-like particles elicit potent neutralizing antibody response in variant challenge

Probiotics significantly improve the symptoms of pregnancy-related problems

Targeting the brain should be the focus of ALS therapy, not just spinal cord

Penn researchers illuminate key molecular details of T-cell exhaustion process

Study documents and visualizes hearing loss-associated genes in the inner ear

SARS-CoV-2 evolution in animals could provide insights on the mutability of COVID-19

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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